AXSM on Nasdaq

Axsome Therapeutics

American biopharmaceutical company.1

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Last updated Oct 16, 2026.

Overview

2012Founded1

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  • TickerAXSM on Nasdaq1
  • IndustryPharmaceutical Preparations1
  • HeadquartersNew York City1
  • Websiteaxsome.com
  • Incorporated inDE3
  • Business addressOne World Trade Center, 29Th Floor, New York, Ny 100073
  • Filer categoryLarge accelerated filer3
Axsome Therapeutics image from its website
Image: axsome.com4

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-26.1%Operating margin5
-28.7%Net margin5
65.5%Revenue growth, 20255
-207.5%Return on equity5
1.33×Debt to equity5
-$93.9MFree cash flow5

What sells

Revenue by product, business segment and region, as the company reports it to the SEC.

Products and services

Product brought in 99% of the revenue Axsome Therapeutics broke down this way in fiscal 2025.

  1. Product$633.8M599%up 66% from 2024
  2. Royalty and Milestone Revenue$4.7M51%up 17% from 2024
Products and services by year
Products and services202320242025
Product$202.5M$381.7M$633.8M
Royalty and Milestone Revenue$2.4M$4.0M$4.7M

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Research and development24¢$183.3M
  • Selling, general and admin74¢$570.6M
  • Interest2¢$15.9M
  • Income tax0¢$530.0K

Out of $638.5M in revenue.5 The company lost money this year.

Financial statements

Revenue65$638.5M in 2025+1176% since 2022
0$200.0M$400.0M$600.0M$800.0M2022: $50.0M$50.0M20222023: $270.6M$270.6M2023+441%2024: $385.7M$385.7M2024+43%2025: $638.5M$638.5M2025+66%
Operating income78965-$166.8M in 2025+148% since 2019
-$300.0M-$200.0M-$100.0M02019: -$67.2M-$67.2M20192020: -$99.1M-$99.1M2020+47%2021: -$124.7M-$124.7M2021+26%2022: -$179.8M-$179.8M2022+44%2023: -$231.8M-$231.8M2023+29%2024: -$280.6M-$280.6M2024+21%2025: -$166.8M-$166.8M2025−41%
Net income78965-$183.2M in 2025+168% since 2019
-$300.0M-$200.0M-$100.0M02019: -$68.3M-$68.3M20192020: -$102.9M-$102.9M2020+51%2021: -$130.4M-$130.4M2021+27%2022: -$187.1M-$187.1M2022+44%2023: -$239.2M-$239.2M2023+28%2024: -$287.2M-$287.2M2024+20%2025: -$183.2M-$183.2M2025−36%

Every line of the income statement in the latest annual report, as filed.5

Period ending2025-12-312024-12-312023-12-31
Revenue$638.5M$385.7M$270.6M
Cost of revenue (excluding amortization and depreciation)$47.5M$33.3M$26.1M
Research and development$183.3M$187.1M$97.9M
Selling, general and administrative$570.6M$411.4M$323.1M
Loss (Gain) in fair value of contingent consideration-$2.5M$28.1M$48.9M
Intangible asset amortization$6.4M$6.4M$6.4M
Total operating expenses$805.3M$666.3M$502.4M
Loss from operations-$166.8M-$280.6M-$231.8M
Interest expense, net-$6.6M-$6.6M-$6.5M
Loss on debt extinguishment-$10.4M
Loss before income taxes-$183.7M-$287.1M-$238.3M
Income tax benefit (expense)$530.0K-$85.0K-$960.0K
Net loss-$183.2M-$287.2M-$239.2M
Net loss per common share, basic-$3.68-$5.99-$5.27
Net loss per common share, diluted-$3.68-$5.99-$5.27
Weighted average common shares outstanding, basic49.7M shares47.9M shares45.4M shares
Weighted average common shares outstanding, diluted49.7M shares47.9M shares45.4M shares

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Timeline

  1. 2012Founded Founded1

Recent filings

  1. Sep 3, 2026144
  2. Sep 3, 20264
  3. Aug 10, 20268-K
  4. Aug 10, 202610-Q
  5. Aug 7, 20264
  6. Aug 6, 2026144
  7. Aug 5, 2026144
  8. Jul 27, 2026SCHEDULE 13G/A
  9. Jul 15, 20268-K
  10. Jul 1, 2026144
  11. Jul 1, 20264
  12. Jun 11, 2026144
  13. Jun 11, 20264
  14. Jun 10, 2026144
  15. Jun 10, 2026144

Every filing from the last three years, summarized. The full record is on SEC EDGAR.2