CBIO on Nasdaq

CRESCENT BIOPHARMA, INC.

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Last updated Oct 16, 2026.

Overview

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  • TickerCBIO on Nasdaq
  • IndustryPharmaceutical Preparations
  • HeadquartersE9
  • Incorporated inCayman Islands2
  • Business address300 Fifth Avenue, Waltham, Ma 024512
  • Filer categoryNon-accelerated filer, Smaller reporting company2

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-1407.5%Operating margin3
-1419.6%Net margin3
-75.8%Return on equity3
-$72.5MFree cash flow3

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Research and development99¢$138.1M
  • Income tax1¢$2.0M

Out of $10.8M in revenue.3 The company lost money this year.

Financial statements

Revenue4563$10.8M in 2025+7% since 2020
0$5.0M$10.0M$15.0M2020: $10.2M$10.2M20202021: $1.2M$1.2M2021−89%2022: $75.0K$75.0K2022−94%2023: $10.0K$10.0K2023−87%2025: $10.8M$10.8M2025+108340%
Operating income74563-$152.6M in 2025+149% since 2019
-$200.0M-$150.0M-$100.0M-$50.0M02019: -$61.4M-$61.4M20192020: -$51.5M-$51.5M2020−16%2021: -$63.4M-$63.4M2021+23%2022: -$47.4M-$47.4M2022−25%2023: -$39.3M-$39.3M2023−17%2024: -$40.0M-$40.0M2024+2%2025: -$152.6M-$152.6M2025+281%
Net income74563-$153.9M in 2025+166% since 2019
-$200.0M-$150.0M-$100.0M-$50.0M02019: -$57.9M-$57.9M20192020: -$51.0M-$51.0M2020−12%2021: -$63.4M-$63.4M2021+24%2022: -$46.7M-$46.7M2022−26%2023: -$36.9M-$36.9M2023−21%2024: -$37.9M-$37.9M2024+3%2025: -$153.9M-$153.9M2025+306%

Every line of the income statement in the latest annual report, as filed.3

Period ending2025-12-31
License revenue$10.8M
Research and development$138.1M
Total operating expenses$163.5M
Loss from operations-$152.6M
Interest income$2.9M
Loss before provision for income taxes-$151.9M
Provision for income taxes-$2.0M
Net loss and comprehensive loss-$153.9M
Net loss and comprehensive loss-$153.9M
Net loss per share attributable to ordinary shareholders, basic (in dollars per share)-$12.81
Net loss per share attributable to ordinary shareholders, diluted (in dollars per share)-$12.81
Net loss per share attributable to Series A non-voting convertible preferred shareholders, basic (in dollars per share)-$12,818.01
Net loss per share attributable to Series A non-voting convertible preferred shareholders, diluted (in dollars per share)-$12,818.01
Weighted-average ordinary shares outstanding used in computing net loss per share to ordinary shareholders, basic (in shares)10.4M shares
Weighted-average ordinary shares outstanding used in computing net loss per share to ordinary shareholders, diluted (in shares)10.4M shares
Weighted-average Series A non-voting convertible preferred shares outstanding used in computing net loss per share to Series A non-voting convertible preferred shareholders, basic (in shares)1.6K shares
Weighted-average Series A non-voting convertible preferred shares outstanding used in computing net loss per share to Series A non-voting convertible preferred shareholders, diluted (in shares)1.6K shares
General and administrative$25.4M
Interest expense$2.2M

Compare CRESCENT BIOPHARMA, INC. with another company

Former names

  • GLYCOMIMETICS INCJul 10, 2003 to Jun 23, 20252

Recent filings

  1. Sep 18, 2026S-8
  2. Sep 18, 20264
  3. Sep 18, 20264
  4. Sep 18, 20264
  5. Sep 18, 20264
  6. Sep 18, 20264
  7. Sep 18, 20264
  8. Sep 18, 20264
  9. Sep 17, 2026144
  10. Sep 17, 2026144
  11. Sep 16, 2026144
  12. Sep 16, 2026144
  13. Aug 14, 2026SCHEDULE 13G/A
  14. Jul 31, 2026EFFECT
  15. Jul 30, 20268-K

Every filing from the last three years, summarized. The full record is on SEC EDGAR.1