Dana–Farber Cancer Institute

In 1947, pediatric pathologist Sidney Farber founded the Children's Cancer Research Foundation (CCRF) with Variety Club to raise money for cancer research. The foundation launched the Jimmy Fund the following year with an advertising campaign featuring a child nicknamed "Jimmy", and constructed the Jimmy Fund Building in the Longwood Medical Area in 1952 to house research facilities. In 1969, the foundation expanded its programs to include patients of all ages, and in 1974 was renamed the Sidney Farber Cancer Center.

In 1962, philanthropist Charles A. Dana, through the Dana Foundation, began financial support of the CCRF. The Dana Building was opened near the Jimmy Fund building in 1975, and in 1983, the organization's name was changed to Dana–Farber Cancer Institute in recognition of the foundation's support.

In 1997, the Smith Research Laboratories building was opened across the street from the Dana Building and the inpatient hospital was moved to Brigham and Women's Hospital, freeing up space for research, laboratories, and adult outpatient care. The Yawkey Center for Cancer Care was opened adjacent to the Smith Laboratories in 2011 to provide additional outpatient facilities.

In September 2023, Dana–Farber Cancer Institute announced a new partnership with Beth Israel Deaconess Medical Center and plans to build a new standalone inpatient hospital focused on treating adult cancer patients. This includes a departure from their current home and longtime affiliation with Brigham and Women's Hospital, which had been recognized among U.S. News & World Report's top cancer care facilities for 23 consecutive years.