HRGN on OTC

Harvard Apparatus Regenerative Technology, Inc.

In its 2026 annual report the company says: “We are a clinical-stage biotechnology company focused on the development of regenerative medicine treatments for disorders of the gastro-intestinal system and other organs that result from cancer, trauma or birth defects. Our technology is based on our proprietary cell-therapy platform that uses a patient’s own stem cells to regenerate and restore function to damaged organs.”3 It is headquartered in Holliston, Massachusetts.1 Its shares trade on OTC under the symbol HRGN.1

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Last updated Oct 20, 2026.

Overview

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  • TickerHRGN on OTC1
  • IndustrySurgical & Medical Instruments & Apparatus1
  • HeadquartersHolliston, Massachusetts1
  • Incorporated inDE2
  • Business address84 October Hill Road, Suite 11, Holliston, Ma 017462
  • Filer categoryNon-accelerated filer, Smaller reporting company2
  • Legal formCorporation

We are a clinical-stage biotechnology company focused on the development of regenerative medicine treatments for disorders of the gastro-intestinal system and other organs that result from cancer, trauma or birth defects. Our technology is based on our proprietary cell-therapy platform that uses a patient’s own stem cells to regenerate and restore function to damaged organs. We believe that our technology represents a next generation solution for restoring organ function because it allows the patient to regenerate their own organ, thus eliminating the need for human donor or animal transplants, the sacrificing of another of the patient’s own organs or permanent artificial implants.3 From its latest annual report

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-982.2%Operating margin4
-975.7%Net margin4
63.7%Revenue growth, 20254
-649.9%Return on equity4

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Cost of revenue20¢$646.0K
  • Research and development80¢$2.7M

Out of $704.0K in revenue.4 The company lost money this year.

Financial statements

Revenue5674$704.0K in 2025
0$200.0K$400.0K$600.0K$800.0K2019: $0$020192020: $0$020202021: $0$020212023: $103.0K$103.0K20232024: $430.0K$430.0K2024+317%2025: $704.0K$704.0K2025+64%
Operating income568974-$6.9M in 2025−22% since 2019
-$10.0M-$7.5M-$5.0M-$2.5M02019: -$8.9M-$8.9M20192020: -$5.3M-$5.3M2020−40%2021: -$8.6M-$8.6M2021+62%2022: -$6.2M-$6.2M2022−29%2023: -$9.0M-$9.0M2023+46%2024: -$7.7M-$7.7M2024−14%2025: -$6.9M-$6.9M2025−10%
Net income568974-$6.9M in 2025−18% since 2019
-$10.0M-$7.5M-$5.0M-$2.5M02019: -$8.3M-$8.3M20192020: -$4.9M-$4.9M2020−42%2021: -$8.0M-$8.0M2021+64%2022: -$6.1M-$6.1M2022−24%2023: -$8.9M-$8.9M2023+47%2024: -$7.7M-$7.7M2024−14%2025: -$6.9M-$6.9M2025−11%

Every line of the income statement as filed: the last 2 fiscal years, latest first.4

Period ending2025-12-312024-12-31
Product revenue$704.0K$430.0K
Cost of sales$646.0K$270.0K
Research and development$2.7M$2.3M
Sales and marketing$67.0K$554.0K
General and administrative$4.3M$5.0M
Total operating expenses$7.6M$8.2M
Operating loss-$6.9M-$7.7M
Interest income$37.0K$32.0K
Interest expense-$8.0K-$38.0K
Other income$17.0K$0
Total other income (expense), net$46.0K-$6.0K
Net loss-$6.9M-$7.7M
Foreign currency translation adjustments-$6.0K-$6.0K
Comprehensive loss-$6.9M-$7.7M
Net loss per common share, basic and diluted (in dollars per share)-$0.42-$0.52
Weighted average common shares outstanding, basic and diluted (in shares)16.5M shares14.8M shares

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Corporate structure

Harvard Apparatus Regenerative Technology, Inc. sits at the top of its group. 1 entity, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.

Major holders of Harvard Apparatus Regenerative Technology, Inc.

  • STELLARS CAPITAL PRIVATE I Ltd Filed SC 13D on Harvard Apparatus Regenerative Technology, Inc., latest Sep 26, 2024
  • DST Capital LLC Filed SC 13D/A on Harvard Apparatus Regenerative Technology, Inc., latest Aug 16, 2024
  • An Zhang Filed SC 13G/A on Harvard Apparatus Regenerative Technology, Inc., latest Feb 16, 2023
  • Harvard Apparatus Regenerative Technology, Inc. Holliston, Massachusetts

Built from major holders from Schedules 13D and 13G. Each entity in the chart links to its source.

What it owns

What Harvard Apparatus Regenerative Technology, Inc. reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.

Property and equipment

ItemLatestA year beforeChange
Property and equipment, before depreciation$1.5M4 Dec 31, 2025$1.5M4 Dec 31, 20240%
Accumulated depreciation$1.5M4 Dec 31, 2025$1.5M4 Dec 31, 2024+0.3%
Property and equipment, net$6.0K4 Dec 31, 2025$11.0K4 Dec 31, 2024−45.5%
Operating-lease assets (leased space)$195.0K4 Dec 31, 2025$293.0K4 Dec 31, 2024−33.4%

Investments

ItemLatestA year beforeChange
Cash and cash equivalents$1.4M4 Dec 31, 2025$2.5M4 Dec 31, 2024−45.6%

Inventory

ItemLatestA year beforeChange
Inventory, total$16.0K4 Dec 31, 2025$80.0K4 Dec 31, 2024−80.0%

Properties, in its own words

On August 12, 2024, the Company entered into an operating lease agreement for approximately 10,629 square feet of office, research and development and light manufacturing space located in located at 84 October Hill Road, Suite 11, Holliston, Massachusetts. The term of the lease ends on August 31, 2027. The space will continue to serve as the Company’s corporate headquarters and incorporate manufacturing, laboratory, development, sales and marketing, and administration functions. We believe our current facilities are adequate for our needs for the foreseeable future.

Item 2 of the 10-K filed Mar 19, 2026.3

Leadership

Who has led Harvard Apparatus Regenerative Technology, Inc., and when. Pick a name to see everywhere that person has worked.

Board members and other officers (18)

Named in SEC Form D filings

People the company listed in its private-offering notices.

  • Executive OfficerHong Yu named Jun 8, 2022 to Sep 14, 202635
  • Executive OfficerShunfu Hu named Jun 8, 2022 to Sep 14, 202635
  • DirectorDavid Green named Jun 8, 2022 to Sep 14, 202635
  • DirectorJing Chen named Jun 8, 2022 to Sep 14, 202635
  • DirectorMao Zhang named Jul 14, 2025 to Sep 14, 202635

Former names

  • Biostage, Inc.Apr 5, 2016 to Jul 10, 20232

Timeline

  1. Sep 14, 20268-K Entered a material agreement; Unregistered sale of shares36
  2. Aug 3, 20268-K Entered a material agreement; New debt or obligation37
  3. Aug 3, 20268-K Entered a material agreement; New debt or obligation38
  4. Jun 24, 20268-K Shareholder vote39
  5. Apr 28, 20268-K Regulation FD disclosure40
  6. Apr 15, 20268-K Ended a material agreement41
  7. Jan 6, 20268-K Entered a material agreement; Unregistered sale of shares42
  8. Jul 14, 20258-K Entered a material agreement; Unregistered sale of shares43
  9. Jun 24, 20258-K Shareholder vote44
  10. Apr 14, 20258-K Change of auditor45
  11. Nov 6, 20248-K Entered a material agreement46
  12. Aug 27, 20248-K Executive or director change47
  13. Apr 12, 2023New chief executive Junli He becomes CEO12
  14. Jul 7, 2015New chief executive James Joseph McGorry becomes CEO14
  15. Jun 1, 2015New chief executive Thomas McNaughton becomes CEO13

Calendar

When it reported results

  1. Nov 14, 2022Reported quarterly or annual results48
  2. Aug 4, 2022Reported quarterly or annual results49
  3. May 16, 2022Reported quarterly or annual results50
  4. Apr 1, 2022Reported quarterly or annual results51
  5. Nov 15, 2021Reported quarterly or annual results52

Upcoming dates from Nasdaq's calendar; past results from the company's 8-K filings (Item 2.02). The full markets calendar

Filings

164 filings to the SEC since October 2021: 5 annual reports, 15 quarterly reports, 44 major events, 72 insider forms, 5 large holders, 6 private raises, 17 other. The latest 20:

  1. Sep 25, 20264 EDGAR
  2. Sep 14, 20268-K EDGAR
  3. Sep 14, 2026D EDGAR
  4. Aug 13, 202610-Q EDGAR
  5. Aug 11, 20264 EDGAR
  6. Aug 3, 20268-K EDGAR
  7. Aug 3, 20268-K/A EDGAR
  8. Jun 24, 20268-K EDGAR
  9. May 13, 202610-Q EDGAR
  10. Apr 28, 20268-K EDGAR
  11. Apr 23, 2026DEF 14A EDGAR
  12. Apr 15, 20268-K EDGAR
  13. Mar 19, 202610-K EDGAR
  14. Jan 6, 2026D EDGAR
  15. Jan 6, 20268-K EDGAR
  16. Dec 1, 20254 EDGAR
  17. Nov 7, 202510-Q EDGAR
  18. Oct 1, 20254 EDGAR
  19. Sep 24, 20254 EDGAR
  20. Sep 2, 20254 EDGAR

The 164 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

25 open-market trades by officers, directors and large owners since October 2021: 21 buys and 4 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Sep 15, 2026He JunliCEOBuy6,725$2.15$14.5KForm 4
Sep 11, 2026He JunliCEOBuy361,905$1.05$380.0KForm 4
Nov 25, 2025He JunliCEOBuy3,000$1.70$5.1KForm 4
Sep 30, 2025He JunliCEOBuy300$1.98$594Form 4
Sep 2, 2025He JunliCEOBuy11,225$1.85$20.8KForm 4
Aug 21, 2025He JunliCEOBuy4,050$1.72$7.0KForm 4
Dec 24, 2024He JunliCEOBuy2,299$2.87$6.6KForm 4
Aug 27, 2024He JunliCEOBuy5,101$3.37$17.2KForm 4
Jun 21, 2024He JunliCEOBuy1,600$2.80$4.5KForm 4
Dec 27, 2023He JunliCEOBuy2,700$4.76$12.9KForm 4
Dec 14, 2023He JunliCEOBuy900$4.92$4.4KForm 4
Dec 6, 2023He JunliCEOBuy1,500$5.07$7.6KForm 4
Sep 11, 2023He JunliCEOBuy1,500$5.43$8.1KForm 4
Aug 28, 2023He JunliCEOBuy3,400$4.69$15.9KForm 4
Aug 21, 2023Shmerling James E.DirectorBuy6,864$4.35$29.9KForm 4
Aug 18, 2023He JunliCEOBuy8,000$4.32$34.6KForm 4
Apr 6, 2023DST Capital LLC10% ownerBuy62,500$6.00$375.0KForm 4
Dec 12, 2022He JunliCEOSale135$6.83$922Form 4
Dec 7, 2022DST Capital LLC10% ownerSale1,952$7.17$14.0KForm 4
Dec 7, 2022Yu HongPRESIDENTSale83,676$7.17$600.0KForm 4

All 25 trades can be filtered by person here when JavaScript is on.

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Executive pay

What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.

YearExecutiveAgeSalaryTotal pay
2025Junli (Jerry) He$423.1K$440.0K56
2025Joseph Damasio$215.8K$227.9K56
2025William FodorPhD$198.8K$210.5K56
2025Hong Yu$177.7K$187.7K56
2024Chief Executive Officer$500.0K$1.3M56
2024Chief Financial Officer$255.0K$268.8K56
2024Chief Scientific Officer$235.0K$248.5K56
2024President$210.0K$221.8K56

Money raised

Private offerings the company reported to the SEC on Form D.

  1. Sep 11, 2026Raised $2.8 million in a private offering of equity Form D: $3 million offered in all Form D
  2. Dec 30, 2025Raised $700,000 in a private offering of equity Form D: $2 million offered in all Form D
  3. Jul 11, 2025Raised $2 million in a private offering of equity Form D: 2 investors so far Form D
  4. Apr 15, 2024Raised $1.5 million in a private offering of equity Form D: 4 investors so far Form D
  5. Mar 31, 2023Raised $6 million in a private offering of equity Form D: 14 investors so far Form D
  6. May 12, 2022Raised $5.1 million in a private offering of equity Form D: 25 investors so far Form D

SEC filer profile

How Harvard Apparatus Regenerative Technology, Inc. is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.

  • Name on EDGARHarvard Apparatus Regenerative Technology, Inc.1
  • CIK0001563665
  • Employer ID (EIN)45-52104623
  • Filer statusNon-accelerated filer not an emerging growth company; a smaller reporting company; not a shell company3
  • Incorporated inDelaware3
  • Fiscal year endsDecember 311
  • Industry code (SIC)3841 Surgical & Medical Instruments & Apparatus1
  • SEC reviewing officeOffice of Industrial Applications and Services, Division of Corporation Finance1
  • Business address84 October Hill Road, Suite 11, Holliston, MA 017461
  • Phone(774) 233-73001
  • Shares outstanding17,580,744 as of Aug 10, 202611
  • Public float$15.6M as of Jun 30, 20253
  • AuditorCBIZ CPAs P.C., Boston, MA PCAOB ID 199; no auditor attestation of internal control over financial reporting3
  • On EDGAR sinceDec 11, 20121
  • Filings625 in all: 4 (196), 8-K (168), 10-Q (39), 3 (33), D (15), DEF 14A (14), SC 13D/A (14), 10-K (13)1
    All 43 form types

    CORRESP (11), SC 13G (11), SC 13G/A (10), DEFA14A (9), UPLOAD (9), S-1/A (8), S-8 (8), SC 13D (7), EFFECT (6), 4/A (5), PRE 14A (5), S-1 (5), 424B3 (3), 424B5 (3), 8-K/A (3), CERTNAS (3), POS AM (3), RW (3), 10-12B/A (2), 8-A12B (2), NT 10-Q (2), S-3 (2), 10-12B (1), 10-K/A (1), 25-NSE (1), 3/A (1), 424B4 (1), ARS (1), CT ORDER (1), D/A (1), DEFR14A (1), DEL AM (1), NT 10-K (1), POS EX (1), PRER14A (1)

  • Latest filingsAnnual report (10-K) Mar 19, 2026
    Quarterly report (10-Q) Aug 13, 2026
    Proxy statement (DEF 14A) Apr 23, 2026
    Latest 8-K (8-K) Sep 14, 2026

Risk factors and legal proceedings

The risks Harvard Apparatus Regenerative Technology, Inc. names in Item 1A of its 10-K filed Mar 19, 2026: 50 risks under these headings, as written.3

  • Risks Relating to Our Financial Position, Need for Capital and Operating Risks
  • Our independent registered public accounting firm’s report contains an explanatory paragraph that expresses substantial doubt about our ability to continue as a “going concern.” Our audited financial statements for the year ended December 31, 2025 contain a going concern qualification. Our financial status creates doubt whether we will continue as a going concern. We will need additional funds in the near future and our operations will be adversely affected if we are unable to obtain needed funding.
  • Our product candidates are in an early stage of development. If we are unable to develop or market any of our product candidates, our financial condition will be negatively affected, and we may have to curtail or cease our operations.
  • We have generated insignificant revenue to date and have an accumulated deficit. We anticipate that we will incur losses for the foreseeable future. We may never achieve or sustain profitability.
  • We have a limited operating history and it is difficult to predict our future growth and operating results.
  • If we fail to retain key personnel and/or attract satisfactory replacements, we may not be able to compete effectively, which would have an adverse effect on our operations.
  • If our collaborators do not devote sufficient time and resources to successfully carry out their duties or meet expected deadlines, we may not be able to advance our product candidates in a timely manner or at all.
  • Public perception of ethical and social issues surrounding the use of cell technology may limit or discourage the use of our technologies, which may reduce the demand for our products and technologies and reduce our revenues.
  • Our products will subject us to liability exposure.
  • If restrictions on reimbursements or other conditions imposed by payers limit our customers’ actual or potential financial returns on our products, our customers may not purchase our products or may reduce their purchases.
  • We depend upon single-source suppliers for the hardware used for our proprietary automatic cell seeder, bioreactor control and acquisition system. The loss of a single source supplier, or future single-source suppliers we may rely on, or their failure to provide us with an adequate supply of their products or services on a timely basis, could adversely affect our business.
  • We use and generate hazardous materials in our business and must comply with environmental laws and regulations, which can be expensive.
The other 39 risks
  • Our products are novel and will require market acceptance.
  • Our long-term growth depends on our ability to develop products for other organs.
  • Our success will depend partly on our ability to operate without infringing on, or misappropriating, the intellectual property or confidentiality rights of others.
  • We may be involved in lawsuits to protect or enforce our patents that would be expensive and time consuming.
  • If we are unable to effectively protect our intellectual property, third parties may use our technology, which would impair our ability to compete in our markets.
  • Intellectual property rights do not necessarily address all potential threats to our competitive advantage.
  • Our competitors and potential competitors may have greater resources than we have and may develop products and technologies that are more effective or commercially attractive than our products and technologies or may develop competing relationships with our key collaborators.
  • Cyber-attacks or other failures in telecommunications or information technology systems and deficiency in our, or those of third parties upon which we rely, cybersecurity could result in information theft, data corruption and significant disruption of our business operations.
  • If we do not successfully manage our growth, our business goals may not be achieved.
  • Risks Associated with Clinical Trials and Pre-Clinical Development
  • The results of our clinical trials or pre-clinical development efforts may not support our product claims or may result in the discovery of adverse side effects.
  • Clinical trials necessary to support a biological product license or other marketing authorization for our product candidates will be expensive and will require the enrollment of sufficient patients to adequately demonstrate safety and efficacy for the product’s target populations. Suitable patients may be difficult to identify and recruit. Delays or failures in our clinical trials will prevent us from commercializing any products and will adversely affect our business, operating results and prospects.
  • If the third parties on which we rely to conduct our clinical trials and to assist us with pre-clinical development do not perform as contractually-required or expected, we may not be able to obtain regulatory approval for or commercialize our product candidates.
  • Risks Associated with Regulatory Approvals
  • If we fail to obtain, or experience significant delays in obtaining, regulatory approvals in the U.S., China or the E.U. for our products, including those for the esophagus and airways, or are unable to maintain such clearances or approvals for our products, our ability to commercially distribute and market these products would be adversely impacted.
  • The FDA has informed us that our esophageal implant would be viewed by the FDA as a combination product comprised of a biologic, or cells, and a medical device component. Nevertheless, we cannot be certain how the FDA will regulate our products. The FDA may require us to obtain marketing clearance and approval from multiple FDA centers. The review of combination products is often more complex and more time consuming than the review of products under the jurisdiction of only one center within the FDA.
  • In the E.U., our esophagus product candidate will likely be regulated as a combined advanced therapy medicinal product and our other product candidates, including for the colon and uterus, may also be viewed as advanced therapy medicinal products, which could delay approvals and clearances and increase costs of obtaining such approvals and clearances.
  • Risk Associated with Product Marketing
  • Even if our products are cleared or approved by regulatory authorities, if we or our suppliers fail to comply with ongoing FDA or other foreign regulatory authority requirements, or if we experience unanticipated problems with our products, these products could be subject to restrictions or withdrawal from the market.
  • Post-market enforcement actions can generate adverse commercial consequences.
  • Economic, political and other risks associated with our international operations could adversely affect our revenues and international growth prospects.
  • We could be negatively impacted by changes in tariffs, trade agreements or other trade restrictions on raw materials and other goods or equipment.
  • Risks Relating to Our Common Stock
  • Our principal stockholders hold a significant percentage of our voting power and will be able to exert significant control over us.
  • A trading market that will provide you with adequate liquidity may not develop for our common stock.
  • Our revenues, operating results and cash flows may fluctuate in future periods and we may fail to meet investor expectations, which may cause the price of our common stock to decline.
  • Substantial sales of common stock have and may continue to occur, or may be anticipated, which have and could continue to cause our stock price to decline.
  • Your percentage ownership will be diluted in the future.
  • Provisions of Delaware law, of our amended and restated charter and amended and restated bylaws may make a takeover more difficult, which could cause our stock price to decline.
  • The market price of our shares may fluctuate widely.
  • Any issuance of preferred stock in the future may dilute the rights of our common stockholders.
  • We do not intend to pay cash dividends on our common stock.
  • Our common stock has been delisted on the NASDAQ Capital Market, which may negatively impact the trading price of our common stock and the levels of liquidity available to our stockholders.
  • If securities or industry analysts do not publish research or reports, or publish unfavorable research or reports, about us, our business or our market, our stock price and trading volume could decline.
  • General Risk Factors
  • We are subject to new U.S. foreign investment regulations, which may impose additional burdens on or may limit certain investors’ ability to purchase our common stock, potentially making our common stock less attractive to investors, and may also impact our ability to generate revenues outside of the U.S.
  • If we incur higher costs as a result of trade policies, treaties, government regulations or tariffs, it could have a materially adverse effect on our business, financial condition or results of operations.
  • We are exposed to a variety of risks relating to our potential international sales and operations, including fluctuations in exchange rates, local economic conditions and delays in collection of accounts receivable.
  • Changes in the European regulatory environment regarding privacy and data protection regulations could have a materially adverse impact on our results of operations.
  • Healthcare legislative reform measures may have a materially adverse effect on our business and results of operations.
  • If we fail to complete the required IRS forms for exemptions, make timely semi-monthly payments of collected excise taxes, or submit quarterly reports as required by the MDET, we may be subject to penalties, such as Section 6656 penalties for any failure to make timely deposits.
  • We are a smaller reporting company and the reduced disclosure requirements applicable to smaller reporting companies may make our common stock less attractive to investors.
  • We incur increased costs as a result of operating as a public company, and our management is required to devote substantial time to new compliance initiatives and corporate governance practices.
  • We will likely in the future have assets held at financial institutions that may exceed the insurance coverage offered by the Federal Deposit Insurance Corporation (“FDIC”), the loss of which would have a severe negative affect on our operations and liquidity.

Legal proceedings

From time to time, we may be involved in various claims and legal proceedings arising in the ordinary course of business. There are no such matters pending that we expect to be material in relation to our business, financial condition, and results of operations or cash flows.

The opening of Item 3, Legal Proceedings.3

Sources

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