Private company

Institute for Systems Biology

American non-profit research institute

The Institute for Systems Biology (ISB) is a non-profit research institution located in Seattle, Washington, United States. ISB concentrates on systems biology, the study of relationships and interactions between various parts of biological systems, and advocates an interdisciplinary approach to biological research.2 It was founded by Leroy Hood, Alan Aderem and Ruedi Aebersold.1 Wikipedia text CC BY-SA 4.0

Last updated Oct 20, 2026.

Overview

2000Founded1
  • HeadquartersSeattle1
  • Websitewww.systemsbiology.org
  • Legal formnon-profit Corporation1
  • LEI549300GAJY38ZVX1UG023
  • StatusActive3
  • LEI statusLapsed (not renewed)3
  • Registered addressC/O CT CORPORATION SYSTEM, 98501-1267 Olympia, United States3
  • Registered withCorporations Division (Office of the Secretary of State), 601 986 3443
Seattle - Institute for Systems Biology 01
Photo: Joe Mabel, CC BY-SA 3.0, via Wikimedia Commons5

The Institute for Systems Biology (ISB) is a non-profit research institution located in Seattle, Washington, United States. ISB concentrates on systems biology, the study of relationships and interactions between various parts of biological systems, and advocates an interdisciplinary approach to biological research.2

The story

Founded by Alan Aderem, Leroy Hood and Ruedi Aebersold in 2000.1

Leroy Hood co-founded the Institute with Alan Aderem and Ruedi Aebersold in 2000.

However, the story of how ISB got started actually begins in 1990. Lee Hood was the director of a large molecular biotechnology lab at the California Institute of Technology in Pasadena, and was a key advisor in the Human Genome Project, having overseen development of machines that were instrumental to its later success. The University of Washington (UW), like many other universities, was eager to recruit Hood, but had neither the space nor the money to accommodate Hood's large laboratory.

Lee Huntsman, director of University of Washington's Center for Bioengineering, was attending a University of Washington football game, sharing a luxury box with Bill Gates, the former CEO and current chairman of Microsoft. Huntsman took the opportunity to tell Gates about Hood. Bill Gates already had a considerable interest in biotechnology, both as a philanthropist and as an investor, and after meeting Hood, donated $12 million to UW to enable him to head a new department of molecular biotechnology, where Hood continues to hold a faculty position as the Gates Professor of Molecular Biotechnology.

ISB represents a spin-off of Hood's labs at UW.

From Wikipedia’s article on Institute for Systems Biology, shared under CC BY-SA 4.0.4

Leadership

Who has led Institute for Systems Biology, and when. Pick a name to see everywhere that person has worked.

Timeline

  1. 2000Founded Founded1