ISCO on OTC
International Stem Cell CORP
American pharmaceutical preparations company, incorporated in Delaware. Summary from the record
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Last updated Oct 19, 2026.
Overview
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- TickerISCO on OTC1
- IndustryPharmaceutical Preparations1
- HeadquartersSan Diego, California1
- Incorporated inDE2
- Business address9745 Businesspark Avenue, San Diego, Ca 921312
- Filer categoryNon-accelerated filer, Smaller reporting company2
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International Stem Cell Corporation (sometimes referred to herein as “ISCO”, the “Company”, “we”, “us”, or “our”) is a clinical stage biotechnology company focused on therapeutic and biomedical product development with multiple long-term therapeutic opportunities and two revenue-generating businesses offering potential for increased future revenue.3 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Key numbers, fiscal 2025
What sells
Revenue by product, business segment and region, as the company reports it to the SEC.
Business segments
Biomedical Market brought in 88% of the revenue International Stem Cell CORP broke down this way in fiscal 2025.
Business segments by year
| Business segments | 2024 | 2025 |
|---|---|---|
| Biomedical Market | $8.3M | $8.5M |
| Anti Aging Market | $795.0K | $598.0K |
| Anti Aging Skincare Market | $795.0K | $598.0K |
Regions
United States brought in 86% of the revenue International Stem Cell CORP broke down this way in fiscal 2025.
Regions by year
| Regions | 2024 | 2025 |
|---|---|---|
| United States | $7.7M | $7.8M |
| Asia | $890.0K | $719.0K |
| Europe | $407.0K | $448.0K |
| Other Regions | $61.0K | $95.0K |
Where the money goes
Where each dollar of revenue went, fiscal 2025
- Cost of revenue44¢$4.0M
- Research and development8¢$684.0K
- Other costs47¢$4.2M
- Interest2¢$151.0K
Out of $9.1M in revenue.4 The company lost money this year.
Where each dollar of operating cash went, fiscal 2025
- Capital spending100¢$43.0K
Out of $8.0K of cash from operations. Spending exceeded cash from operations; the rest came from savings or borrowing.4
Financial statements
Every line of the income statement as filed: the last 2 fiscal years, latest first.4
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Product sales | $9.1M | $9.1M |
| Cost of sales | $4.0M | $3.8M |
| General and administrative | $3.5M | $3.5M |
| Selling and marketing | $1.1M | $1.2M |
| Research and development | $684.0K | $657.0K |
| Total operating expenses | $9.4M | $9.2M |
| Loss from operations | -$267.0K | -$68.0K |
| Interest expense | -$6.0K | -$7.0K |
| Interest expense - related party | -$145.0K | -$138.0K |
| Other income, net | $4.0K | |
| Other expense, net | -$151.0K | -$141.0K |
| Net loss | -$418.0K | -$209.0K |
| Net loss per common share, basic | -$0.05 | -$0.03 |
| Net loss per common share, diluted | -$0.05 | -$0.03 |
| Weighted-average common shares used to compute net loss per share, basic | 8.0M shares | 8.0M shares |
| Weighted-average common shares used to compute net loss per share, diluted | 8.0M shares | 8.0M shares |
No quarter-by-quarter statement was filed.
Every line of the balance sheet as filed: the last 4 fiscal years (annual) or 4 quarters (quarterly), latest first.4
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2008-06-30 |
|---|---|---|---|---|
| Cash | $993.0K | $1.2M | ||
| Accounts receivable, net | $723.0K | $1.1M | ||
| Inventories | $1.5M | $1.1M | ||
| Prepaid expenses and other current assets | $181.0K | $123.0K | ||
| Total current assets | $3.4M | $3.6M | ||
| Non-current inventories | $229.0K | $252.0K | ||
| Property and equipment, net | $160.0K | $257.0K | ||
| Intangible assets, net | $644.0K | $721.0K | ||
| Right-of-use assets | $344.0K | $352.0K | ||
| Deposits and other assets | $31.0K | $31.0K | ||
| Total assets | $4.8M | $5.2M | ||
| Accounts payable | $168.0K | $186.0K | ||
| Accrued liabilities | $428.0K | $527.0K | ||
| Operating lease liabilities, current | $393.0K | $330.0K | ||
| Advances | $250.0K | $250.0K | $250.0K | |
| Related party note payable | $3.3M | $3.4M | ||
| Total current liabilities | $4.6M | $4.7M | ||
| Operating lease liabilities, net of current portion | $0 | $115.0K | ||
| Total liabilities | $4.6M | $4.8M | ||
| Common stock, $0.001 par value; 120,000,000 shares authorized; 8,004,389 shares issued and outstanding at December 31, 2025 and 2024 | $8.0K | $8.0K | ||
| Additional paid-in capital | $107.0M | $106.7M | ||
| Accumulated deficit | -$111.1M | -$110.7M | ||
| Total stockholders' deficit | -$4.1M | -$3.9M | -$4.2M | |
| Total liabilities, redeemable convertible preferred stock and stockholders' deficit | $4.8M | $5.2M | ||
| Non-redeemable convertible preferred stock, par value | $0.00 | $0.00 | ||
| Non-redeemable convertible preferred stock, shares authorized | 20.0M shares | 20.0M shares | ||
| Common stock, par value | $0.00 | $0.00 | ||
| Common stock, shares authorized | 120.0M shares | 120.0M shares | ||
| Common stock, shares issued | 8.0M shares | 8.0M shares | ||
| Common stock, shares outstanding | 8.0M shares | 8.0M shares |
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2008-06-30 |
|---|---|---|---|---|
| Cash | $993.0K | $1.2M | ||
| Accounts receivable, net | $723.0K | $1.1M | ||
| Inventories | $1.5M | $1.1M | ||
| Prepaid expenses and other current assets | $181.0K | $123.0K | ||
| Total current assets | $3.4M | $3.6M | ||
| Non-current inventories | $229.0K | $252.0K | ||
| Property and equipment, net | $160.0K | $257.0K | ||
| Intangible assets, net | $644.0K | $721.0K | ||
| Right-of-use assets | $344.0K | $352.0K | ||
| Deposits and other assets | $31.0K | $31.0K | ||
| Total assets | $4.8M | $5.2M | ||
| Accounts payable | $168.0K | $186.0K | ||
| Accrued liabilities | $428.0K | $527.0K | ||
| Operating lease liabilities, current | $393.0K | $330.0K | ||
| Advances | $250.0K | $250.0K | $250.0K | |
| Related party note payable | $3.3M | $3.4M | ||
| Total current liabilities | $4.6M | $4.7M | ||
| Operating lease liabilities, net of current portion | $0 | $115.0K | ||
| Total liabilities | $4.6M | $4.8M | ||
| Common stock, $0.001 par value; 120,000,000 shares authorized; 8,004,389 shares issued and outstanding at December 31, 2025 and 2024 | $8.0K | $8.0K | ||
| Additional paid-in capital | $107.0M | $106.7M | ||
| Accumulated deficit | -$111.1M | -$110.7M | ||
| Total stockholders' deficit | -$4.1M | -$3.9M | -$4.2M | |
| Total liabilities, redeemable convertible preferred stock and stockholders' deficit | $4.8M | $5.2M | ||
| Non-redeemable convertible preferred stock, par value | $0.00 | $0.00 | ||
| Non-redeemable convertible preferred stock, shares authorized | 20.0M shares | 20.0M shares | ||
| Common stock, par value | $0.00 | $0.00 | ||
| Common stock, shares authorized | 120.0M shares | 120.0M shares | ||
| Common stock, shares issued | 8.0M shares | 8.0M shares | ||
| Common stock, shares outstanding | 8.0M shares | 8.0M shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 2 fiscal years, latest first.4
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Net loss | -$418.0K | -$209.0K |
| Stock-based compensation | $288.0K | $466.0K |
| Depreciation and amortization | $219.0K | $206.0K |
| Non-cash operating lease expense | $310.0K | $205.0K |
| Interest expense on related party note payable | $145.0K | $138.0K |
| Change in inventory reserve | $45.0K | $14.0K |
| Impairment of intangible assets | $2.0K | |
| Accounts receivable | $335.0K | -$484.0K |
| Inventories | -$387.0K | $114.0K |
| Prepaid expenses and other current assets | -$58.0K | -$27.0K |
| Accounts payable | -$18.0K | -$178.0K |
| Accrued liabilities | -$99.0K | $42.0K |
| Operating lease liabilities | -$354.0K | -$276.0K |
| Net cash provided by operating activities | $8.0K | $13.0K |
| Purchases of property and equipment | -$43.0K | -$166.0K |
| Payments for patent licenses | -$2.0K | -$5.0K |
| Net cash used in investing activities | -$45.0K | -$171.0K |
| Principal repayment on note payable from related party | -$200.0K | -$200.0K |
| Net cash used in financing activities | -$200.0K | -$200.0K |
| Net decrease in cash | -$237.0K | -$358.0K |
| Operating lease right-of-use asset obtained in exchange for operating lease liabilities | $302.0K | |
| Cash paid for interest | $6.0K | $10.0K |
No quarter-by-quarter statement was filed.
Leadership
Who has led International Stem Cell CORP, and when. Pick a name to see everywhere that person has worked.
Chief executive
Chief financial officer
Chief operating officer
- Chief executive officerRouslan Semechkin Jan 17, 2012 to Jan 17, 201212
- Chief executive officerAndrei Semechkin Dec 15, 2009 to Nov 8, 202313
- Chief executive officerKenneth C. Aldrich Apr 24, 2008 to Nov 9, 200914
- Chief executive officerJeff Krstich Jan 3, 2007 to Jan 3, 200715
- Chief executive officerTimothy P. Halter Jun 8, 2006 to Jun 8, 200616
- ChairKenneth C. Aldrich Jan 3, 2007 to Nov 9, 200917
- ChairTimothy P. Halter Jun 8, 2006 to Jun 8, 200616
- PresidentKurt Andrew May Oct 13, 2011 to Oct 13, 201118
- PresidentBrian Lundstrom Nov 9, 2009 to Dec 21, 201019
- PresidentJeffrey Janus Jan 3, 2007 to Dec 31, 200820
- Chief financial officerJennifer Stephens Aug 30, 2017 to Aug 30, 201721
- Chief financial officerMahnaz Ebrahimi Sep 16, 2015 to Jun 1, 201722
- Chief financial officerTibor Jay Novak Apr 25, 2013 to Nov 12, 201423
- Chief financial officerEdmund R. Wood Jun 30, 2010 to Mar 3, 201124
- Chief financial officerWilliam B. Adams Jan 3, 2007 to Jan 2, 200925
- Chief financial officerTimothy P. Halter Jun 8, 2006 to Jun 8, 200616
- Chief operating officerKurt Andrew May Oct 13, 2011 to Oct 13, 201118
Board members and other officers (16)
- Dir. of Legal Affairs & Oper.Sofya Bakalova Aug 13, 2014 to Jun 11, 202126
- Vice PresidentRouslan Semechkin Mar 12, 2012 to Nov 8, 202327
- Executive Vice PresidentJohn Simon Craw Jun 8, 2012 to Mar 13, 201528
- Chief Business OfficerAndrei Semechkin Jan 2, 2009 to Dec 14, 200929
- VICE PRESIDENT, OPERATIONSJeffrey Janus Nov 9, 2009 to Jan 14, 201130
- VP Finance & SecretaryEdmund R. Wood Dec 15, 2009 to Dec 15, 200931
- Board memberJames H. Berglund Mar 22, 2012 to Jun 21, 201332
- Board memberCharles J. Casamento Jun 22, 2010 to Jun 25, 201833
- Board memberKenneth C. Aldrich Dec 29, 2010 to Feb 8, 201134
- Board memberAndrei Semechkin Jan 26, 2009 to Nov 8, 202335
- Board memberWilliam B. Adams Apr 24, 2008 to Jan 2, 200936
- Board memberRouslan Semechkin Oct 14, 2008 to Nov 8, 202337
- Board memberWright Don Jul 20, 2007 to now38
- Board memberPaul Maier V. Jul 24, 2007 to now39
- Board memberEdward O. Hunter Jul 31, 2007 to Dec 31, 200840
- Board memberJeffrey Janus Sep 7, 2007 to Jun 26, 201241
Former names
- BTHC III INC.Apr 4, 2006 to Jan 19, 20072
Timeline
- Jan 17, 2012New chief executive Rouslan Semechkin becomes CEO12
- Dec 15, 2009New chief executive Andrei Semechkin becomes CEO13
- Apr 24, 2008New chief executive Kenneth C. Aldrich becomes CEO14
- Jan 3, 2007New chief executive Jeff Krstich becomes CEO15
- Jun 8, 2006New chief executive Timothy P. Halter becomes CEO16
Filings
68 filings to the SEC since October 2021: 5 annual reports, 15 quarterly reports, 17 major events, 17 insider forms, 14 other. The latest 20:
- Sep 17, 20264 EDGAR
- Sep 15, 20264 EDGAR
- Sep 11, 2026144 EDGAR
- Sep 8, 20268-K EDGAR
- Aug 13, 202610-Q EDGAR
- Aug 4, 2026DEF 14C DEFINITIVE INFORMATION STATEMENT EDGAR
- Jul 24, 2026PRE 14C PRELIMINARY INFORMATION STATEMENT EDGAR
- Jul 16, 20268-K CURRENT REPORT EDGAR
- Jun 23, 20264 EDGAR
- Jun 23, 20264 EDGAR
- Jun 12, 20268-K CURRENT REPORT EDGAR
- May 14, 202610-Q EDGAR
- Apr 29, 2026ARS EDGAR
- Apr 29, 2026DEF 14A EDGAR
- Mar 30, 202610-K EDGAR
- Nov 18, 20258-K CURRENT REPORT EDGAR
- Nov 13, 202510-Q EDGAR
- Sep 16, 20258-K CURRENT REPORT EDGAR
- Aug 14, 202510-Q EDGAR
- Jun 20, 20254 EDGAR
The 68 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
1 open-market trades by officers, directors and large owners since October 2021: 0 buys and 1 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Sep 11, 2026 | MAIER PAUL VDirector | Sale | 32,802 | $0.32 | $10.5K | Form 4 |
From Forms 4 filed with the SEC.
Sources
The numbers on this page point here. Each one links to the record it came from.
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- 17SEC EDGARKenneth C. Aldrich, Chair
- 18SEC EDGARKurt Andrew May, President
- 19SEC EDGARBrian Lundstrom, President
- 20SEC EDGARJeffrey Janus, President
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- 27SEC EDGARRouslan Semechkin, Vice President
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- 32SEC EDGARJames H. Berglund, Board member
- 33SEC EDGARCharles J. Casamento, Board member
- 34SEC EDGARKenneth C. Aldrich, Board member
- 35SEC EDGARAndrei Semechkin, Board member
- 36SEC EDGARWilliam B. Adams, Board member
- 37SEC EDGARRouslan Semechkin, Board member
- 38SEC EDGARWright Don, Board member
- 39SEC EDGARPaul Maier V., Board member
- 40SEC EDGAREdward O. Hunter, Board member
- 41SEC EDGARJeffrey Janus, Board member