JAZZ on Nasdaq

Jazz Pharmaceuticals

Irish tax-registered pharmaceutical corporation

Jazz Pharmaceuticals plc (a merger of Jazz Pharmaceuticals, Inc. and Azur Pharma plc) is an American global biopharmaceutical company with a focus on oncology and neuroscience.3 From Wikipedia, CC BY-SA 4.0

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Last updated Oct 19, 2026.

Overview

2003Founded1

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  • TickerJAZZ on Nasdaq1
  • Industrypharmaceutical industry1
  • HeadquartersIreland1
  • Websitewww.jazzpharma.com
  • Legal formpublic limited company1
  • Incorporated inIreland4
  • Business addressFifth Floor, Waterloo Exchange, Waterloo Road, Dublin, D04 E5W74
  • Filer categoryLarge accelerated filer4

Jazz Pharmaceuticals plc (a merger of Jazz Pharmaceuticals, Inc. and Azur Pharma plc) is an American global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.3

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-10.1%Operating margin6
-8.3%Net margin6
4.9%Revenue growth, 20256
-8.2%Return on equity6
1.00×Debt to equity6
$1.3BFree cash flow6

What sells

Revenue by product, business segment and region, as the company reports it to the SEC.

Products and services

Total Oncology brought in 29% of the revenue Jazz Pharmaceuticals broke down this way in fiscal 2025.

  1. Total Oncology$1.1B629%up 2% from 2024
  2. Epidiolex/Epidyolex$1.1B627%up 9% from 2024
  3. Rylaze/Enrylaze$402.9M610%down 2% from 2024
  4. Zepzelca$307.3M68%down 4% from 2024
  5. Product And Services, Royalties And Contract Revenue$245.7M66%down 1% from 2024
  6. High Sodium A G Oxybate Product Royalty Revenue$211.7M65%down 3% from 2024
  7. Defitelio/Defibrotide$199.4M65%down 8% from 2024
  8. Vyxeos$146.7M64%down 10% from 2024
  9. Xyrem$146.0M64%down 38% from 2024
  10. Modeyso$48.0M61%
  11. Other Royalties And Contract Revenue$34.0M61%up 13% from 2024
  12. Ziihera$24.8M61%up 2261% from 2024
Products and services by year
Products and services202320242025
Total Oncology$1.0B$1.1B$1.1B
Epidiolex/Epidyolex$845.5M$972.4M$1.1B
Rylaze/Enrylaze$394.2M$410.8M$402.9M
Zepzelca$289.5M$320.3M$307.3M
Product And Services, Royalties And Contract Revenue$97.3M$247.8M$245.7M
High Sodium A G Oxybate Product Royalty Revenue$75.9M$217.6M$211.7M
Defitelio/Defibrotide$184.0M$216.6M$199.4M
Vyxeos$147.5M$162.6M$146.7M
Xyrem$569.7M$233.8M$146.0M
Modeyso$0$0$48.0M
Other Royalties And Contract Revenue$21.3M$30.2M$34.0M
Ziihera$0$1.1M$24.8M

Regions

United States brought in 90% of the revenue Jazz Pharmaceuticals broke down this way in fiscal 2025.

  1. United States$3.8B690%up 5% from 2024
  2. Europe$341.1M68%up 9% from 2024
  3. Other Countries$94.9M62%down 1% from 2024
Regions by year
Regions202320242025
United States$3.5B$3.7B$3.8B
Europe$269.2M$312.7M$341.1M
Other Countries$75.0M$96.1M$94.9M

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Selling, general and admin42¢$1.8B
  • Other costs51¢$2.2B
  • Income tax6¢$272.4M

Out of $4.3B in revenue.6 The company lost money this year.

Where each dollar of operating cash went, fiscal 2025

  • Capital spending4¢$58.8M
  • Share buybacks9¢$125.0M
  • Kept or used elsewhere86¢$1.2B

Out of $1.4B of cash from operations.6

Financial statements

Revenue789106$4.3B in 2025+97% since 2019
0$2.0B$4.0B$6.0B2019: $2.2B$2.2B20192020: $2.4B$2.4B2020+9%2021: $3.1B$3.1B2021+31%2022: $3.7B$3.7B2022+18%2023: $3.8B$3.8B2023+5%2024: $4.1B$4.1B2024+6%2025: $4.3B$4.3B2025+5%
Operating income789106-$430.2M in 2025
-$500.0M0$500.0M$1.0B2019: $532.4M$532.4M20192020: $378.1M$378.1M2020−29%2021: $170.3M$170.3M2021−55%2022: -$65.5M-$65.5M20222023: $578.6M$578.6M20232024: $716.6M$716.6M2024+24%2025: -$430.2M-$430.2M2025
Net income789106-$356.1M in 2025
-$500.0M-$250.0M0$250.0M$500.0M$750.0M2019: $523.4M$523.4M20192020: $238.6M$238.6M2020−54%2021: -$329.7M-$329.7M20212022: -$224.1M-$224.1M2022−32%2023: $414.8M$414.8M20232024: $560.1M$560.1M2024+35%2025: -$356.1M-$356.1M2025

Every line of the income statement as filed: the last 3 fiscal years, latest first.6

Period ending2025-12-312024-12-312023-12-31
Total revenues$4.3B$4.1B$3.8B
Cost of product sales (excluding amortization of acquired developed technologies)$503.3M$445.7M$435.6M
Selling, general and administrative$1.8B$1.4B$1.3B
Research and development$782.7M$884.0M$849.7M
Intangible asset amortization$654.7M$627.3M$608.3M
Acquired in-process research and development$947.9M$10.0M$19.0M
Total operating expenses$4.7B$3.4B$3.3B
Income (loss) from operations-$430.2M$716.6M$578.6M
Interest expense, net-$195.1M-$238.1M-$289.4M
Foreign exchange gain (loss)-$2.6M-$8.2M$8.8M
Income (loss) before income tax benefit and equity in loss of investees-$627.9M$470.4M$297.9M
Income tax benefit-$272.4M-$91.4M-$119.9M
Equity in loss of investees$732.0K$1.7M$3.0M
Net income (loss)-$356.1M$560.1M$414.8M
Basic (in dollars per share)-$5.84$9.06$6.55
Diluted (in dollars per share)-$5.84$8.65$6.10
Weighted-average ordinary shares used in per share calculations - basic (in shares)61.0M shares61.8M shares63.3M shares
Weighted-average ordinary shares used in per share calculations - diluted (in shares)61.0M shares66.0M shares72.1M shares

Compare Jazz Pharmaceuticals with another company

How it started

2010–2019

On 18 February 2010, the FDA accepted a new drug application for JZP-6 (Sodium oxybate) for the treatment of Fibromyalgia. In the following December, a new patent was issued for Sodium Oxybate.

On September 19, 2011, Jazz Pharmaceuticals merged with Irish Azur Pharma plc to form Jazz Pharmaceuticals plc. The Azur Pharma seat in Dublin became the headquarters of the combined company. Azur Pharma had been marketing specialty pharmaceutical products in the central nervous system (CNS) and women's health areas with US operations in Philadelphia.

On 26 April 2012, the company acquired EUSA Pharma for $650 million (plus $50 million in milestone payments). In September, the company sold its Women's Health business to Meda for $95 million. In December, the company began clinical trial of intravenous Erwinaze in patients with Acute Lymphoblastic Leukemia.

In January 2014, the company announced it would acquire the rare disease drug developer Gentium SpA and its lead product Defitelio for $1 billion.

In May 2016, the company announced it would acquire Alizé Pharma II for $20.5 million. At the end of the same month, the company announced its then largest acquisition, with the purchase of Celator Pharmaceuticals for $1.5 billion. As a result, Jazz obtained the rights to breakthrough therapy Vyxeos (liposomal daunorubicin and cytarabine) for treatment of acute myeloid leukemia.

From Wikipedia’s article on Jazz Pharmaceuticals, shared under CC BY-SA 4.0.3

Leadership

Who has led Jazz Pharmaceuticals, and when. Pick a name to see everywhere that person has worked.

Board members and other officers (46)

Products and brands

  • medication

Listed on Wikidata.1

Subsidiaries and ownership

Subsidiaries

From Wikidata.1

Acquisitions

2010–2019

On 18 February 2010, the FDA accepted a new drug application for JZP-6 (Sodium oxybate) for the treatment of Fibromyalgia. In the following December, a new patent was issued for Sodium Oxybate.

On September 19, 2011, Jazz Pharmaceuticals merged with Irish Azur Pharma plc to form Jazz Pharmaceuticals plc. The Azur Pharma seat in Dublin became the headquarters of the combined company. Azur Pharma had been marketing specialty pharmaceutical products in the central nervous system (CNS) and women's health areas with US operations in Philadelphia.

On 26 April 2012, the company acquired EUSA Pharma for $650 million (plus $50 million in milestone payments). In September, the company sold its Women's Health business to Meda for $95 million. In December, the company began clinical trial of intravenous Erwinaze in patients with Acute Lymphoblastic Leukemia.

In January 2014, the company announced it would acquire the rare disease drug developer Gentium SpA and its lead product Defitelio for $1 billion.

Read the full text

In May 2016, the company announced it would acquire Alizé Pharma II for $20.5 million. At the end of the same month, the company announced its then largest acquisition, with the purchase of Celator Pharmaceuticals for $1.5 billion. As a result, Jazz obtained the rights to breakthrough therapy Vyxeos (liposomal daunorubicin and cytarabine) for treatment of acute myeloid leukemia.

In August 2019, the company announced it would acquire Cavion Inc. for up to $310 million.

2020–present

In January 2021, Jazz announced it would acquire cannabis-focused medicinal drug company GW Pharmaceuticals for US$7.2 billion. This acquisition added the medication Epidiolex (cannabidiol), developed to treat severe epilepsy syndromes, to the company's portfolio.

In November 2025, Jazz Pharmaceuticals announced positive results from its Phase 3 trial for its cancer drug, Ziihera, a potential treatment for advanced gastroesophageal cancer.

Acquisition history

The following is an illustration of the company's mergers, acquisitions, spin-offs and historical predecessors:

From Wikipedia’s article on Jazz Pharmaceuticals, shared under CC BY-SA 4.0.5

Former names

  • JAZZ PHARMACEUTICALS INCMay 12, 2003 to Jan 18, 20124

Timeline

  1. Aug 11, 2025New chief executive Renee D. Gala becomes CEO14
  2. Jun 2, 2009New chief executive Bruce C. Cozadd becomes CEO15
  3. May 31, 2007New chief executive Samuel R. Saks becomes CEO16
  4. 2003Founded Founded1

Filings

566 filings to the SEC since October 2021: 10 annual reports, 15 quarterly reports, 66 major events, 298 insider forms, 17 large holders, 160 other. The latest 20:

  1. Oct 9, 20268-K EDGAR
  2. Oct 8, 2026144 EDGAR
  3. Oct 7, 20264 PRIMARY DOCUMENT EDGAR
  4. Oct 6, 2026144 EDGAR
  5. Oct 5, 20264 PRIMARY DOCUMENT EDGAR
  6. Oct 1, 2026144 EDGAR
  7. Sep 23, 20268-K EDGAR
  8. Sep 15, 20268-K EDGAR
  9. Sep 14, 20264 PRIMARY DOCUMENT EDGAR
  10. Sep 10, 20264 PRIMARY DOCUMENT EDGAR
  11. Sep 10, 2026144 EDGAR
  12. Sep 10, 20264 PRIMARY DOCUMENT EDGAR
  13. Sep 8, 2026144 EDGAR
  14. Sep 8, 2026144 EDGAR
  15. Sep 2, 20264 PRIMARY DOCUMENT EDGAR
  16. Sep 2, 20264 PRIMARY DOCUMENT EDGAR
  17. Sep 2, 20264 PRIMARY DOCUMENT EDGAR
  18. Sep 2, 20264 PRIMARY DOCUMENT EDGAR
  19. Sep 2, 20264 PRIMARY DOCUMENT EDGAR
  20. Sep 2, 20264 PRIMARY DOCUMENT EDGAR

The 566 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

153 open-market trades by officers, directors and large owners since October 2021: 3 buys and 150 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Sep 10, 2026Patil Neena MEVP & Chief Legal OfficerSale1,200$240.94$289.1KForm 4
Sep 8, 2026GALA RENEE DPresident & CEOSale2,000$243.03$486.1KForm 4
Sep 1, 2026COZADD BRUCE CDirectorSale6,000$250.13$1.5MForm 4
Aug 27, 2026Iannone RobertEVP, Global Head of R&D & CMOSale76,921$249.70$19.2MForm 4
Aug 3, 2026COZADD BRUCE CDirectorSale6,000$252.98$1.5MForm 4
Jul 1, 2026COZADD BRUCE CDirectorSale6,000$240.47$1.4MForm 4
Jun 15, 2026Smith Mark DouglasDirectorSale1,157$230.55$266.7KForm 4
Jun 10, 2026Patil Neena MEVP & Chief Legal OfficerSale1,200$231.83$278.2KForm 4
Jun 1, 2026COZADD BRUCE CDirectorSale6,000$235.12$1.4MForm 4
May 28, 2026Pearce SamanthaEVP, Chief Commercial OfficerSale6,907$235.41$1.6MForm 4
May 28, 2026Patil Neena MEVP & Chief Legal OfficerSale1,192$236.97$282.5KForm 4
May 22, 2026McSharry Heather AnnDirectorSale2,000$241.00$482.0KForm 4
May 22, 2026Winningham Rick EDirectorSale2,741$241.57$662.1KForm 4
May 1, 2026COZADD BRUCE CDirectorSale6,000$203.33$1.2MForm 4
Apr 1, 2026COZADD BRUCE CDirectorSale6,000$190.50$1.1MForm 4
Mar 9, 2026Carr PatriciaSVP, Chief Accounting OfficerSale1,287$182.94$235.4KForm 4
Mar 3, 2026COZADD BRUCE CDirectorSale6,000$186.44$1.1MForm 4
Feb 27, 2026Carr PatriciaSVP, Chief Accounting OfficerSale1,117$190.91$213.2KForm 4
Feb 27, 2026RIEDEL NORBERT GDirectorSale3,415$192.00$655.7KForm 4
Feb 26, 2026Henderson Mary ElizabethSVP, Technical OperationsSale5,343$194.49$1.0MForm 4

All 153 trades can be filtered by person here when JavaScript is on.

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Members of Congress who traded it

4 trades disclosed by members of Congress. “Vs S&P since” is the stock’s change since the trade minus the S&P 500’s.

DateMemberTradeAmountVs S&P sinceFiling
Jul 12, 2023Daniel S. GoldmanDemocratic, HouseSale$15,001 - $50,000+1.9%Report
Mar 6, 2023Daniel S. GoldmanDemocratic, HouseBuy$15,001 - $50,000−40.6%Report
Jan 31, 2023Daniel S. GoldmanDemocratic, HouseSale$1,001 - $15,000+53.0%Report
Oct 19, 2021Thomas R. SuozziDemocratic, HouseBuy$1,001 - $15,000−22.4%Report

Members report amounts as ranges, not exact figures. Returns are price-only (no dividends).

Sources

The numbers on this page point here. Each one links to the record it came from.

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