MAZE on Nasdaq

Maze Therapeutics, Inc.

American biological products company, incorporated in Delaware.

Price unavailable

Last updated Oct 18, 2026.

Overview

-$131.1MNet income, fiscal 20252

Compare with REGENXBIO Inc., Adaptimmune (United Kingdom) or Aerie Pharmaceuticals, or pick any stock.

  • TickerMAZE on Nasdaq
  • IndustryBiological Products, (No Diagnostic Substances)
  • HeadquartersDE
  • Incorporated inDE3
  • Business address171 Oyster Point Boulevard, Suite 300, South San Francisco, Ca 940803
  • Filer category, Emerging growth company3

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2024

34.4%Operating margin2
31.2%Net margin2
$74.8MFree cash flow2

Where the money goes

Where each dollar of revenue went, fiscal 2024

  • Research and development50¢$83.5M
  • Other costs18¢$30.6M
  • Income tax1¢$1.2M
  • Profit31¢$52.2M

Out of $167.5M in revenue.2

Where each dollar of operating cash went, fiscal 2024

  • Capital spending2¢$1.1M
  • Kept or used elsewhere98¢$74.8M

Out of $76.0M of cash from operations.2

Financial statements

Every line of the income statement as filed: the last 2 fiscal years, latest first.2

Period ending2025-12-312024-12-31
License revenue$167.5M
Research and development$108.4M$83.5M
General and administrative$34.5M$26.4M
Total operating expenses$142.9M$109.9M
(Loss) income from operations-$142.9M$57.6M
Interest and other income, net$11.8M$4.7M
Change in fair value of convertible promissory notes$0-$8.8M
(Loss) income before income tax expense-$131.1M$53.4M
Income tax expense$0-$1.2M
Net (loss) income-$131.1M$52.2M
Net (loss) income attributable to common stockholders, basic (see Note 14)-$131.1M$3.4M
Net (loss) income attributable to common stockholders, diluted (see Note 14)-$131.1M$3.4M
Basic-$3.05$1.42
Diluted-$3.05$1.25
Basic43.0M shares2.4M shares
Diluted43.0M shares2.7M shares
Net unrealized gain on marketable securities$110.0K
Comprehensive (loss) income-$131.0M$52.2M

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Leadership

Who has led Maze Therapeutics, Inc., and when. Pick a name to see everywhere that person has worked.

Board members and other officers (19)

Timeline

  1. Jan 30, 2025New chief executive Jason Coloma V. becomes CEO6

Filings

217 filings to the SEC since October 2021: 2 annual reports, 5 quarterly reports, 15 major events, 106 insider forms, 24 large holders, 65 other. The latest 20:

  1. Oct 2, 20264 EDGAR
  2. Oct 2, 20264 EDGAR
  3. Oct 1, 20264 EDGAR
  4. Oct 1, 2026144 EDGAR
  5. Oct 1, 2026144 EDGAR
  6. Sep 8, 20264 EDGAR
  7. Sep 4, 20264 EDGAR
  8. Sep 4, 20264 EDGAR
  9. Sep 4, 2026144 EDGAR
  10. Sep 4, 20264 EDGAR
  11. Sep 4, 20264 EDGAR
  12. Sep 3, 20264 EDGAR
  13. Sep 3, 20264 EDGAR
  14. Sep 3, 20264 EDGAR
  15. Sep 3, 20264 EDGAR
  16. Sep 2, 2026144 EDGAR
  17. Sep 2, 2026144 EDGAR
  18. Sep 2, 2026144 EDGAR
  19. Sep 2, 2026144 EDGAR
  20. Sep 1, 2026144 EDGAR

The 217 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last three years, summarized. The full record is on SEC EDGAR.

Insider trades and holders

Large holders

Investors who own more than 5% must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively. 24 such filings since October 2021, the latest 10:

  1. Aug 14, 2026SCHEDULE 13G/A
  2. Jul 29, 2026SCHEDULE 13G
  3. May 15, 2026SCHEDULE 13G/A
  4. Apr 1, 2026SCHEDULE 13G
  5. Feb 13, 2026SCHEDULE 13G/A
  6. Feb 13, 2026SCHEDULE 13G/A
  7. Feb 6, 2026SCHEDULE 13G/A
  8. Nov 14, 2025SCHEDULE 13G/A
  9. Nov 14, 2025SCHEDULE 13G/A
  10. Nov 13, 2025SCHEDULE 13G/A

From Forms 4 and Schedules 13D and 13G filed with the SEC.

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
Frazier Life Sciences Management, L.P.5,032,915$150.2M3.3%+465,641
Trv Gp Iv, LLC4,473,958$133.5M52.6%No change
ARCH Venture Management, LLC4,120,053$123.0M11.2%No change
Deep Track Capital, LP3,732,569$111.4M1.6%+255,007
BlackRock, Inc.3,502,841$104.5M0.0%+932,416
Jupiter Topco LLC3,408,045$101.8M0.0%New
Logos Global Management LP1,935,000$57.7M2.5%+700,000
Vanguard Capital Management LLC1,778,222$53.1M0.0%+342,566
a16z Capital Management, L.L.C.1,702,225$50.8M0.4%No change
Venrock Adviser, LLC1,602,034$47.8M1.4%No change
Alphabet Inc.1,388,583$41.4M0.0%No change
Braidwell LP1,140,040$34.0M1.3%New
Farallon Capital Management, L.l.c.1,107,814$33.1M0.2%+734,814
Fmr LLC1,056,959$31.5M0.0%+192,745
General Catalyst Group Management, LLC1,035,910$30.9M16.4%No change
State Street Corp997,533$29.8M0.0%+360,811
Driehaus Capital Management LLC954,886$28.5M0.2%+318,724
Trv Gp V, LLC950,800$28.4M5.7%No change
Jpmorgan Chase & Co964,011$28.0M0.0%+905,565
Marshall Wace, Llp914,572$27.3M0.0%+603,933
Geode Capital Management, LLC858,054$25.6M0.0%+258,087
Citadel Advisors LLC852,676$25.4M0.0%+76,962
Casdin Capital, LLC843,857$25.2M1.3%+85,000
ArrowMark Colorado Holdings LLC767,383$22.9M1.0%No change
Woodline Partners LP736,216$22.0M0.1%+85,987

13F reports cover disclosed long positions in U.S. stocks only.