MBRX on Nasdaq
Moleculin Biotech, Inc.
American pharmaceutical preparations company based in Houston. Summary from the record
Price unavailable
Last updated Oct 19, 2026.
Overview
- TickerMBRX on Nasdaq2
- IndustryPharmaceutical Preparations2
- HeadquartersHouston, United States2
- Incorporated inDE3
- Business address5300 Memorial Drive, Suite 950, Houston, Tx 770073
- Filer categoryNon-accelerated filer, Smaller reporting company3
- Legal formCorporation2
- LEI549300IB1TLJZCHEO3532
- StatusActive2
- LEI statusLapsed (not renewed)2
- Registered addressC/O CORPORATION SERVICE COMPANY, 19808 Wilmington, United States2
- Registered withDivision of Corporations, Department of State, 57932652
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We are a late-stage pharmaceutical development company currently evaluating Annamycin, also known as L-Annamycin and by its generic name “naxtarubicin”, which we believe is a “next-generation” anthracycline and, with it, are conducting a pivotal Phase 3 trial in combination with cytarabine for the treatment of subjects with relapsed/refractory (R/R) acute myeloid leukemia (AML). We call this the “MIRACLE” trial (derived from Moleculin R/R AML AnnAraC Clinical Evaluation). A blinded preliminary data readout has been released for the MIRACLE trial, and we expect to have an interim unblinding of data in mid-2026 and an additional unblinding in the second half of 2026, thereby concluding Part A of the two-part trial. We believe such early visibility for a pivotal registration-enabling trial is unique in that stakeholders will receive preliminary safety and efficacy data long before the concl…4 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Key numbers, fiscal 2025
Financial statements
Every line of the income statement as filed: the last 2 fiscal years, latest first.5
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Revenue | $0 | $0 |
| Research and development | $15.9M | $17.7M |
| General and administrative | $9.1M | $8.8M |
| Depreciation and amortization | $90.0K | $126.0K |
| Total operating expenses | $25.1M | $26.6M |
| Loss from operations | -$25.1M | -$26.6M |
| Gain from change in fair value of warrant liabilities | $24.4M | $0 |
| Loss on issuance of warrant liabilities | -$31.0M | $0 |
| Transaction costs allocated to warrant liabilities | -$1.4M | $0 |
| Loss on extinguishment of warrant liabilities | -$614.0K | $0 |
| Other (expense) income, net | -$20.0K | $43.0K |
| Interest income, net | $105.0K | $550.0K |
| Net loss | -$33.6M | -$26.0M |
| Warrant deemed dividend | -$104.0K | $0 |
| Net loss available to common stockholders | -$33.7M | -$26.0M |
| Net loss per common share - basic and diluted (in dollars per share) | -$28.42 | -$189.14 |
| Weighted average common shares outstanding, basic and diluted (in shares) | 1.2M shares | 137.7K shares |
| Foreign currency translation | $51.0K | -$32.0K |
| Comprehensive loss | -$33.5M | -$26.1M |
No quarter-by-quarter statement was filed.
Every line of the balance sheet as filed: the last 5 fiscal years (annual) or 5 quarters (quarterly), latest first.5
| Period ending | 2025-12-31 | 2025-08-31 | 2025-05-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|---|---|
| Cash and cash equivalents | $8.9M | $4.3M | |||
| Prepaid expenses and other current assets | $808.0K | $916.0K | |||
| Total current assets | $9.7M | $5.2M | |||
| Furniture and equipment, net | $78.0K | $159.0K | |||
| Intangible assets | $11.1M | $11.1M | |||
| Other non-current assets | $900.0K | $900.0K | $0 | ||
| Operating lease right-of-use asset | $314.0K | $424.0K | |||
| Total Assets | $22.1M | $16.9M | |||
| Accounts payable | $3.5M | $2.0M | |||
| Accrued expenses and other current liabilities | $3.3M | $3.3M | |||
| Total current liabilities | $6.9M | $5.4M | |||
| Operating lease liability - long-term, net of current portion | $222.0K | $358.0K | |||
| Warrant liability | $44.0K | $0 | |||
| Total Liabilities | $7.1M | $5.7M | |||
| Preferred stock, $0.001 par value; 5,000,000 authorized shares, no shares issued or outstanding | $0 | $0 | |||
| Common stock, $0.001 par value; 500,000,000 and 100,000,000 authorized shares as of December 31, 2025 and December 31, 2024, respectively, 3,199,228 and 135,155 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | $3.0K | $0 | |||
| Additional paid-in capital | $221.0M | $183.7M | |||
| Accumulated other comprehensive income (loss) | $10.0K | -$41.0K | |||
| Accumulated deficit | -$206.0M | -$172.4M | -$146.4M | ||
| Total stockholders' equity | $15.0M | $11.2M | $30.9M | ||
| Total liabilities and stockholders' equity | $22.1M | $16.9M | |||
| Preferred stock, par value (in dollars per share) | $0.00 | $0.00 | |||
| Preferred stock, shares authorized (in shares) | 5.0M shares | 5.0M shares | |||
| Preferred stock, shares issued (in shares) | 0 shares | 0 shares | |||
| Preferred stock, shares outstanding (in shares) | 0 shares | 0 shares | |||
| Common stock, par value (in dollars per share) | $0.00 | $0.00 | |||
| Common stock, shares authorized (in shares) | 500.0M shares | 500.0M shares | 100.0M shares | ||
| Common stock, shares issued (in shares) | 3.2M shares | 135.2K shares | |||
| Common stock, shares outstanding (in shares) | 3.2M shares | 135.2K shares |
| Period ending | 2025-12-31 | 2025-08-31 | 2025-05-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|---|---|
| Cash and cash equivalents | $8.9M | $4.3M | |||
| Prepaid expenses and other current assets | $808.0K | $916.0K | |||
| Total current assets | $9.7M | $5.2M | |||
| Furniture and equipment, net | $78.0K | $159.0K | |||
| Intangible assets | $11.1M | $11.1M | |||
| Other non-current assets | $900.0K | $900.0K | $0 | ||
| Operating lease right-of-use asset | $314.0K | $424.0K | |||
| Total Assets | $22.1M | $16.9M | |||
| Accounts payable | $3.5M | $2.0M | |||
| Accrued expenses and other current liabilities | $3.3M | $3.3M | |||
| Total current liabilities | $6.9M | $5.4M | |||
| Operating lease liability - long-term, net of current portion | $222.0K | $358.0K | |||
| Warrant liability | $44.0K | $0 | |||
| Total Liabilities | $7.1M | $5.7M | |||
| Preferred stock, $0.001 par value; 5,000,000 authorized shares, no shares issued or outstanding | $0 | $0 | |||
| Common stock, $0.001 par value; 500,000,000 and 100,000,000 authorized shares as of December 31, 2025 and December 31, 2024, respectively, 3,199,228 and 135,155 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | $3.0K | $0 | |||
| Additional paid-in capital | $221.0M | $183.7M | |||
| Accumulated other comprehensive income (loss) | $10.0K | -$41.0K | |||
| Accumulated deficit | -$206.0M | -$172.4M | -$146.4M | ||
| Total stockholders' equity | $15.0M | $11.2M | $30.9M | ||
| Total liabilities and stockholders' equity | $22.1M | $16.9M | |||
| Preferred stock, par value (in dollars per share) | $0.00 | $0.00 | |||
| Preferred stock, shares authorized (in shares) | 5.0M shares | 5.0M shares | |||
| Preferred stock, shares issued (in shares) | 0 shares | 0 shares | |||
| Preferred stock, shares outstanding (in shares) | 0 shares | 0 shares | |||
| Common stock, par value (in dollars per share) | $0.00 | $0.00 | |||
| Common stock, shares authorized (in shares) | 500.0M shares | 500.0M shares | 100.0M shares | ||
| Common stock, shares issued (in shares) | 3.2M shares | 135.2K shares | |||
| Common stock, shares outstanding (in shares) | 3.2M shares | 135.2K shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 2 fiscal years, latest first.5
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Net loss | -$33.6M | -$26.0M |
| Depreciation and amortization | $90.0K | $126.0K |
| Stock-based compensation | $1.7M | $1.7M |
| Change in fair value of warrant liabilities | -$24.4M | $0 |
| Loss on issuance of warrant liabilities | $31.0M | $0 |
| Transaction costs allocated to warrant liabilities | $1.4M | $0 |
| Loss on extinguishment of warrant liabilities | $614.0K | $0 |
| Operating lease, net | -$26.0K | $103.0K |
| Prepaid expenses and other assets | -$792.0K | $1.8M |
| Accounts payable | $1.3M | -$468.0K |
| Accrued expenses and other liabilities | $17.0K | -$1.1M |
| Net cash used in operating activities | -$22.7M | -$23.9M |
| Purchase of fixed assets | $0 | -$13.0K |
| Net cash used in investing activities | $0 | -$13.0K |
| Proceeds from sale of common stock, pre-funded and common warrants and warrant inducement, net of issuance and transaction costs | $25.8M | $4.7M |
| Proceeds from exercise of warrants | $1.5M | $1.0K |
| Payment of tax liability for vested restricted stock units | -$8.0K | -$26.0K |
| Net cash provided by financing activities | $27.3M | $4.6M |
| Net increase (decrease) in cash and cash equivalents | $4.6M | -$19.3M |
| Effect of exchange rate changes on cash and cash equivalents | $51.0K | -$32.0K |
| Reclassification of warrant liabilities to equity pursuant to warrant amendments | $16.7M | $0 |
| Equity warrants issued in relation to liability-classified warrant inducements | $6.2M | $0 |
| Offering costs included in accounts payable and accrued liabilities | $138.0K | $0 |
| Deemed dividend in connection with warrant amendment | $104.0K | $0 |
| Transaction costs related to the sale of common stock, pre-funded and common warrants | $0 | $156.0K |
No quarter-by-quarter statement was filed.
Leadership
Who has led Moleculin Biotech, Inc., and when. Pick a name to see everywhere that person has worked.
Chief executive
Chair
Chief financial officer
Chief operating officer
- Chief executive officerWalter Klemp V. Jun 7, 2016 to now13
- ChairWalter Klemp V. Jun 7, 2016 to Jun 7, 201613
- PresidentWalter Klemp V. Jun 8, 2018 to now14
- PresidentDonald H. Picker Aug 8, 2016 to Aug 8, 201615
- Chief financial officerLouis Ploth Jr. Jun 7, 2016 to Jun 7, 201616
- Chief financial officerJonathan P. Foster Aug 23, 2016 to now17
- Chief operating officerDonald H. Picker Aug 8, 2016 to Aug 8, 201615
Board members and other officers (8)
- Chief Science OfficerDonald H. Picker Oct 5, 2017 to now18
- Board memberJoy Yan Mar 2, 2022 to now19
- Board memberElizabeth Cermak Oct 5, 2020 to now20
- Board memberWalter Klemp V. May 12, 2017 to now21
- Board memberJohn M. Climaco Jul 26, 2017 to now22
- Board memberJacqueline Northcut Jun 7, 2016 to May 5, 201723
- Board memberMichael D. Cannon Jun 7, 2016 to now24
- Board memberRobert E. George Jun 7, 2016 to now25
Timeline
Filings
451 filings to the SEC since October 2021: 9 annual reports, 15 quarterly reports, 235 major events, 77 insider forms, 9 large holders, 106 other. The latest 20:
- Oct 15, 2026S-8 EDGAR
- Oct 9, 20268-K EDGAR
- Oct 5, 20268-K EDGAR
- Sep 29, 20268-K EDGAR
- Sep 28, 20268-K EDGAR
- Sep 25, 20268-K EDGAR
- Sep 23, 20268-K EDGAR
- Sep 18, 20268-K EDGAR
- Sep 14, 20268-K EDGAR
- Aug 31, 20268-K EDGAR
- Aug 25, 2026SCHEDULE 13D EDGAR
- Aug 25, 2026SCHEDULE 13D EDGAR
- Aug 24, 2026DEFA14A EDGAR
- Aug 24, 2026DEF 14A EDGAR
- Aug 21, 2026424B5 EDGAR
- Aug 14, 2026PRE 14A EDGAR
- Aug 14, 20268-K EDGAR
- Aug 13, 202610-Q EDGAR
- Aug 10, 2026SCHEDULE 13G EDGAR
- Aug 6, 2026SCHEDULE 13G EDGAR
The 451 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
12 open-market trades by officers, directors and large owners since October 2021: 12 buys and 0 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Aug 3, 2026 | Foster Jonathan P.Chief Financial Officer | Buy | 293,333 | Form 4 | ||
| Aug 3, 2026 | KLEMP WALTER VCEO and President | Buy | 533,333 | Form 4 | ||
| Aug 3, 2026 | PICKER DONALD HChief Science Officer | Buy | 173,333 | Form 4 | ||
| Jun 23, 2025 | Foster Jonathan P.Chief Financial Officer | Buy | 270,270 | $0.37 | $100.0K | Form 4 |
| Jun 23, 2025 | KLEMP WALTER VCEO and President | Buy | 675,675 | $0.37 | $250.0K | Form 4 |
| Dec 26, 2023 | Foster Jonathan P.Chief Financial Officer | Buy | 28,986 | $0.69 | $20.0K | Form 4 |
| Dec 26, 2023 | George Robert E.Director | Buy | 14,493 | $0.69 | $10.0K | Form 4 |
| Dec 26, 2023 | KLEMP WALTER VCEO and President | Buy | 188,404 | $0.69 | $130.0K | Form 4 |
| Nov 25, 2022 | KLEMP WALTER VCEO and President | Buy | 45,000 | $1.28 | $57.6K | Form 4 |
| Nov 21, 2022 | KLEMP WALTER VCEO and President | Buy | 22,500 | $1.15 | $25.9K | Form 4 |
| Nov 17, 2022 | KLEMP WALTER VCEO and President | Buy | 24,742 | $1.02 | $25.2K | Form 4 |
| Nov 16, 2022 | KLEMP WALTER VCEO and President | Buy | 85,213 | $0.97 | $82.7K | Form 4 |
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
- Jonathan P. FosterSCHEDULE 13D, 1 filing Aug 25, 202626
- Walter Klemp V.SCHEDULE 13D, 1 filing Aug 25, 202627
- CVI Investments, Inc.SCHEDULE 13G, 1 filing Aug 10, 202628
- INTRACOASTAL CAPITAL, LLCSCHEDULE 13G, 1 filing Aug 6, 202629
- ARMISTICE CAPITAL, LLCSCHEDULE 13G/A, 5 filings Feb 14, 2024 to Aug 14, 202530
Held by these funds
The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026. Change is in shares since the quarter before.
| Fund | Shares | Value | Share of the fund | Change |
|---|---|---|---|---|
| Geode Capital Management, LLC | 47,252 | $131.8K | 0.0% | +14,923 |
| Vanguard Capital Management LLC | 42,215 | $117.8K | 0.0% | +28,346 |
| Vanguard Fiduciary Trust Co | 29,883 | $83.4K | 0.0% | +23,811 |
| XTX Topco Ltd | 22,942 | $64.0K | 0.0% | New |
| Morgan Stanley | 20,036 | $55.9K | 0.0% | +20,000 |
| Rockefeller Capital Management L.P. | 15,000 | $41.9K | 0.0% | +10,579 |
| Tower Research Capital LLC (TRC) | 3,514 | $9.8K | 0.0% | +1,679 |
| Citigroup Inc | 2,674 | $7.5K | 0.0% | New |
| Barclays PLC | 621 | $1.7K | 0.0% | New |
| BlackRock, Inc. | 491 | $1.4K | 0.0% | No change |
| EFG International AG | 434 | $1.2K | 0.0% | No change |
| Jones Financial Companies Lllp | 360 | $1.2K | 0.0% | New |
| Wells Fargo & Company/mn | 200 | $558 | 0.0% | New |
| NFSG Corp | 114 | $318 | 0.0% | No change |
| SBI Securities Co., Ltd. | 44 | $123 | 0.0% | +1 |
| Danske Bank A/s | 2 | $6 | 0.0% | No change |
| CVA Family Office, LLC | 1 | $3 | 0.0% | No change |
| Osaic Holdings, Inc. | 1 | $2 | 0.0% | No change |
13F reports cover disclosed long positions in U.S. stocks only.
Sources
The numbers on this page point here. Each one links to the record it came from.
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- 14SEC EDGARWalter Klemp V., President
- 15SEC EDGARDonald H. Picker, President
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- 19SEC EDGARJoy Yan, Board member
- 20SEC EDGARElizabeth Cermak, Board member
- 21SEC EDGARWalter Klemp V., Board member
- 22SEC EDGARJohn M. Climaco, Board member
- 23SEC EDGARJacqueline Northcut, Board member
- 24SEC EDGARMichael D. Cannon, Board member
- 25SEC EDGARRobert E. George, Board member
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