MLYS on Nasdaq

Mineralys Therapeutics, Inc.

Pharmaceutical preparations company based in Radnor, listed on Nasdaq (MLYS).

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Last updated Oct 18, 2026.

Overview

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  • TickerMLYS on Nasdaq
  • IndustryPharmaceutical Preparations
  • Business address150 N. Radnor Chester Road, Suite F200, Radnor, Pa2
  • Filer categoryNon-accelerated filer, Smaller reporting company, Emerging growth company2

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Financial statements

Operating income345-$170.6M in 2025+442% since 2022
-$200.0M-$150.0M-$100.0M-$50.0M02022: -$31.5M-$31.5M20222023: -$84.7M-$84.7M2023+169%2024: -$192.4M-$192.4M2024+127%2025: -$170.6M-$170.6M2025−11%
Net income345-$154.7M in 2025+419% since 2022
-$200.0M-$150.0M-$100.0M-$50.0M02022: -$29.8M-$29.8M20222023: -$71.9M-$71.9M2023+141%2024: -$177.8M-$177.8M2024+147%2025: -$154.7M-$154.7M2025−13%

Every line of the income statement as filed: the last 2 fiscal years, latest first.5

Period ending2025-12-312024-12-31
Research and development$132.0M$168.6M
General and administrative$38.6M$23.8M
Total operating expenses$170.6M$192.4M
Loss from operations-$170.6M-$192.4M
Interest income, net$16.0M$14.6M
Other income$0$5.0K
Total other income, net$16.0M$14.6M
Net loss-$154.7M-$177.8M
Net loss per share attributable to common stockholders - basic (in USD per share)-$2.29-$3.66
Net loss per share attributable to common stockholders - diluted (in USD per share)-$2.29-$3.66
Weighted-average shares used to compute net loss per share attributable to common stockholders - basic (in shares)67.7M shares48.5M shares
Weighted-average shares used to compute net loss per share attributable to common stockholders - diluted (in shares)67.7M shares48.5M shares

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Leadership

Who has led Mineralys Therapeutics, Inc., and when. Pick a name to see everywhere that person has worked.

2025
Board members and other officers (15)

Timeline

  1. Feb 9, 2023New chief executive Jon Congleton becomes CEO8

Filings

400 filings to the SEC since October 2021: 4 annual reports, 11 quarterly reports, 46 major events, 176 insider forms, 23 large holders, 1 private raises, 139 other. The latest 20:

  1. Oct 13, 2026144 EDGAR
  2. Oct 2, 20264 EDGAR
  3. Sep 30, 2026144 EDGAR
  4. Sep 24, 20264 EDGAR
  5. Sep 22, 2026144 EDGAR
  6. Sep 22, 20264 EDGAR
  7. Sep 21, 2026144 EDGAR
  8. Sep 17, 2026144 EDGAR
  9. Sep 17, 20264 EDGAR
  10. Sep 15, 2026144 EDGAR
  11. Sep 14, 2026144 EDGAR
  12. Sep 9, 2026144 EDGAR
  13. Aug 25, 20264 EDGAR
  14. Aug 21, 2026144 EDGAR
  15. Aug 17, 2026144 EDGAR
  16. Aug 13, 2026144 EDGAR
  17. Aug 12, 20264 EDGAR
  18. Aug 12, 20263 EDGAR
  19. Aug 12, 20264 EDGAR
  20. Aug 11, 202610-Q EDGAR

The 400 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last three years, summarized. The full record is on SEC EDGAR.

Insider trades and holders

Large holders

Investors who own more than 5% must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively. 23 such filings since October 2021, the latest 10:

  1. Aug 6, 2026SCHEDULE 13G/A
  2. Feb 13, 2026SCHEDULE 13G/A
  3. Feb 5, 2026SCHEDULE 13G
  4. Jan 21, 2026SCHEDULE 13G
  5. Sep 8, 2025SCHEDULE 13D/A
  6. Sep 8, 2025SCHEDULE 13D/A
  7. Aug 14, 2025SCHEDULE 13G/A
  8. Aug 14, 2025SCHEDULE 13G/A
  9. Mar 17, 2025SCHEDULE 13D/A
  10. Mar 17, 2025SCHEDULE 13D/A

From Forms 4 and Schedules 13D and 13G filed with the SEC.

Money raised

Private offerings the company reported to the SEC on Form D.

  1. Jun 1, 2022Raised $118 million in a private offering of equity Form D: 23 investors so far Form D

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
Catalys Pacific, LLC7,903,838$213.2M92.9%No change
Ra Capital Management, L.P.7,692,750$207.6M1.8%No change
BlackRock, Inc.5,887,038$158.8M0.0%+1,405,456
Samsara Biocapital, LLC5,871,018$158.4M13.0%No change
Fmr LLC4,511,689$121.7M0.0%−349,415
State Street Corp4,141,636$111.7M0.0%+1,205,696
Deerfield Management Company, L.P.3,958,000$106.8M1.3%New
Vanguard Capital Management LLC2,756,770$74.4M0.0%+302,407
Laurion Capital Management LP2,506,152$67.6M5.1%+274,112
Orbimed Advisors LLC2,110,300$56.9M1.1%+57,400
Capital World Investors1,997,607$53.9M0.0%+1,599,428
Armistice Capital, LLC1,736,000$46.8M1.3%+560,000
Troluce Capital Advisors LLC1,728,753$46.6M17.5%+1,073,753
Nantahala Capital Management, LLC1,640,962$44.3M1.3%+745,481
Franklin Resources Inc1,635,520$44.1M0.0%−149,142
Andera Partners1,591,917$42.9M20.8%No change
Geode Capital Management, LLC1,584,326$42.8M0.0%+283,191
SR One Capital Management, LP1,563,966$42.2M4.1%No change
Bank Of America Corp /de/1,505,547$40.6M0.0%+405,175
Sphera Funds Management Ltd.1,469,971$39.7M5.7%+130,000
Goldman Sachs Group Inc1,458,676$39.4M0.0%+673,633
Pictet Asset Management Holding SA1,430,649$38.6M0.0%+396,211
Polar Capital Holdings Plc1,420,854$38.3M0.1%−79,895
Millennium Management LLC1,221,758$33.0M0.0%+696,498
Ghisallo Capital Management LLC1,125,000$30.4M0.7%New

13F reports cover disclosed long positions in U.S. stocks only.