NKTX on Nasdaq
Nkarta Therapeutics (United States)
We are a clinical-stage biopharmaceutical company pioneering the development of allogeneic, off-the-shelf engineered natural killer ("NK") cell therapies.4 From its latest annual report
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Last updated Oct 19, 2026.
Overview
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- TickerNKTX on Nasdaq1
- Industrybiotechnology industry1
- HeadquartersSouth San Francisco, California1
- Websitewww.nkartatx.com
- Incorporated inDE3
- Business address1150 Veterans Boulevard, South San Francisco, Ca 940803
- Filer categoryNon-accelerated filer, Smaller reporting company3
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We are a clinical-stage biopharmaceutical company pioneering the development of allogeneic, off-the-shelf engineered natural killer ("NK") cell therapies. Our company was founded on the belief that engineered NK cell therapies can transform the lives of patients by offering therapies that are clinically meaningful, broadly accessible and unencumbered by the safety concerns often associated with other cell therapy approaches. Our lead pipeline program is NKX019, a chimeric antigen receptor-natural killer ("CAR NK") product candidate targeting the CD19 antigen for the treatment of patients with autoimmune diseases. Our CAR NK platform enables an on-demand, off-the-shelf approach involving scaled manufacturing to broaden patient access. We have developed proprietary technologies designed to generate an abundant supply of NK cells, increase NK cell recognition of target antigens, and enhance…4 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Key numbers, fiscal 2025
Financial statements
Every line of the income statement as filed: the last 2 fiscal years, latest first.5
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Research and development | $90.4M | $96.7M |
| General and administrative | $31.6M | $31.4M |
| Total operating expenses | $122.0M | $128.2M |
| Loss from operations | -$122.0M | -$128.2M |
| Interest income | $15.5M | $19.3M |
| Other income, net | $2.4M | $87.0K |
| Total other income, net | $17.9M | $19.4M |
| Net Income (Loss) | -$104.1M | -$108.8M |
| Net unrealized (loss) gain on investments | -$267.0K | $666.0K |
| Comprehensive loss | -$104.4M | -$108.1M |
| Net loss per share, basic | -$1.41 | -$1.60 |
| Net loss per share, diluted | -$1.41 | -$1.60 |
| Weighted average shares outstanding used in computing net loss per share, basic | 74.0M shares | 67.9M shares |
| Weighted average shares outstanding used in computing net loss per share, diluted | 74.0M shares | 67.9M shares |
No quarter-by-quarter statement was filed.
Every line of the balance sheet as filed: the last 4 fiscal years (annual) or 4 quarters (quarterly), latest first.5
| Period ending | 2025-12-31 | 2024-12-31 | 2024-05-31 | 2023-12-31 |
|---|---|---|---|---|
| Cash and cash equivalents | $39.6M | $27.9M | ||
| Short-term investments | $236.6M | $239.5M | ||
| Prepaid expenses and other current assets | $6.2M | $6.0M | ||
| Total current assets | $282.5M | $273.3M | ||
| Long-term investments | $16.1M | $110.4M | ||
| Restricted cash | $2.7M | $2.7M | ||
| Property and equipment, net | $66.7M | $74.7M | ||
| Operating lease right-of-use assets | $34.4M | $36.0M | ||
| Other long-term assets | $1.7M | $4.1M | ||
| Total assets | $404.2M | $501.2M | ||
| Accounts payable | $2.1M | $638.0K | ||
| Operating lease liabilities, current portion | $6.9M | $6.0M | ||
| Accrued and other current liabilities | $13.3M | $12.2M | ||
| Total current liabilities | $22.3M | $18.9M | ||
| Operating lease liabilities, net of current portion | $69.5M | $74.2M | ||
| Other long-term liabilities | $87.0K | $87.0K | ||
| Total liabilities | $91.9M | $93.2M | ||
| Common stock,$0.0001 par value; 200,000,000 shares authorized as of December 31, 2025 and 2024; 71,078,531 and 70,645,139 shares issued and outstanding at December 31, 2025 and 2024,respectively | $7.0K | $7.0K | ||
| Additional paid-in capital | $960.2M | $951.5M | ||
| Accumulated other comprehensive income | $407.0K | $674.0K | ||
| Accumulated deficit | -$648.3M | -$544.2M | ||
| Total stockholders' equity | $312.3M | $408.0M | $273.3M | |
| Total liabilities and stockholders' equity | $404.2M | $501.2M | ||
| Preferred stock, par value | $0.00 | $0.00 | ||
| Preferred stock, shares authorized | 54.4M shares | 54.4M shares | ||
| Preferred stock, shares issued | 0 shares | 0 shares | ||
| Preferred stock, shares outstanding | 0 shares | 0 shares | ||
| Common stock, par value | $0.00 | $0.00 | $0.00 | |
| Common stock, shares authorized | 200.0M shares | 200.0M shares | 100.0M shares | |
| Common stock, shares issued | 71.1M shares | 70.6M shares | ||
| Common stock, shares outstanding | 71.1M shares | 70.6M shares |
| Period ending | 2025-12-31 | 2024-12-31 | 2024-05-31 | 2023-12-31 |
|---|---|---|---|---|
| Cash and cash equivalents | $39.6M | $27.9M | ||
| Short-term investments | $236.6M | $239.5M | ||
| Prepaid expenses and other current assets | $6.2M | $6.0M | ||
| Total current assets | $282.5M | $273.3M | ||
| Long-term investments | $16.1M | $110.4M | ||
| Restricted cash | $2.7M | $2.7M | ||
| Property and equipment, net | $66.7M | $74.7M | ||
| Operating lease right-of-use assets | $34.4M | $36.0M | ||
| Other long-term assets | $1.7M | $4.1M | ||
| Total assets | $404.2M | $501.2M | ||
| Accounts payable | $2.1M | $638.0K | ||
| Operating lease liabilities, current portion | $6.9M | $6.0M | ||
| Accrued and other current liabilities | $13.3M | $12.2M | ||
| Total current liabilities | $22.3M | $18.9M | ||
| Operating lease liabilities, net of current portion | $69.5M | $74.2M | ||
| Other long-term liabilities | $87.0K | $87.0K | ||
| Total liabilities | $91.9M | $93.2M | ||
| Common stock,$0.0001 par value; 200,000,000 shares authorized as of December 31, 2025 and 2024; 71,078,531 and 70,645,139 shares issued and outstanding at December 31, 2025 and 2024,respectively | $7.0K | $7.0K | ||
| Additional paid-in capital | $960.2M | $951.5M | ||
| Accumulated other comprehensive income | $407.0K | $674.0K | ||
| Accumulated deficit | -$648.3M | -$544.2M | ||
| Total stockholders' equity | $312.3M | $408.0M | $273.3M | |
| Total liabilities and stockholders' equity | $404.2M | $501.2M | ||
| Preferred stock, par value | $0.00 | $0.00 | ||
| Preferred stock, shares authorized | 54.4M shares | 54.4M shares | ||
| Preferred stock, shares issued | 0 shares | 0 shares | ||
| Preferred stock, shares outstanding | 0 shares | 0 shares | ||
| Common stock, par value | $0.00 | $0.00 | $0.00 | |
| Common stock, shares authorized | 200.0M shares | 200.0M shares | 100.0M shares | |
| Common stock, shares issued | 71.1M shares | 70.6M shares | ||
| Common stock, shares outstanding | 71.1M shares | 70.6M shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 2 fiscal years, latest first.5
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Net loss | -$104.1M | -$108.8M |
| Share-based compensation expense | $8.6M | $16.7M |
| Depreciation and amortization expense | $9.2M | $9.2M |
| Accretion of discount and amortization of premium on investments, net | -$4.6M | -$6.9M |
| Non-cash lease expense | $2.0M | $2.3M |
| Realized gain on investments | -$94.0K | |
| Impairment of right-of-use asset | $791.0K | |
| Prepaid expenses and other assets | $2.1M | -$1.4M |
| Operating lease liabilities | -$5.0M | -$6.4M |
| Accounts payable and accrued and other liabilities | $2.5M | -$4.5M |
| Other long-term liabilities | $87.0K | |
| Net cash used in operating activities | -$88.7M | -$99.7M |
| Purchases of investments | -$238.6M | -$406.4M |
| Proceeds from maturities of investments | $340.1M | $281.2M |
| Purchases of property and equipment | -$1.2M | -$4.4M |
| Net cash provided by (used in) investing activities | $100.3M | -$129.6M |
| Proceeds from issuance of common stock and pre-funded warrants, net of issuance costs | $225.1M | |
| Proceeds from employee stock purchase plan purchases | $141.0K | $343.0K |
| Proceeds from stock option exercises | $0 | $668.0K |
| Net cash provided by financing activities | $141.0K | $226.1M |
| Net increase (decrease) in cash and cash equivalents | $11.8M | -$3.2M |
| Acquisitions of property and equipment recorded in accounts payable and accrued and other current liabilities | $390.0K | $343.0K |
| Right-of-use assets recognized in exchange for operating lease liability | $1.2M | $579.0K |
| Decrease in right-of-use asset and lease liability due to termination | $2.2M |
No quarter-by-quarter statement was filed.
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Leadership
Who has led Nkarta Therapeutics (United States), and when. Pick a name to see everywhere that person has worked.
Chief executive
President
Chief financial officer
- Chief executive officerPaul J. Hastings Jan 12, 2021 to now13
- PresidentNadir Mahmood Jul 31, 2024 to now14
- Chief financial officerMatthew Plunkett Jul 9, 2020 to Jul 13, 202015
Board members and other officers (23)
- OfficerShawn Marshall Rose Jun 25, 2025 to now16
- Chief Medical OfficerDavid Shook Jan 10, 2023 to now17
- OfficerAlyssa Levin Jul 5, 2023 to now18
- Sr. VP, Technical OperationsRalph Brandenberger Mar 31, 2021 to now19
- Chief Scientific OfficerJames Trager Jul 9, 2020 to Jun 20, 202420
- Chief Medical OfficerKanya Rajangam Jul 9, 2020 to Jan 19, 202221
- Chief Business OfficerNadir Mahmood Jul 9, 2020 to Jun 22, 202322
- OfficerPaul J. Hastings Jul 9, 2020 to Jul 13, 202023
- Board memberGeorge Vratsanos Jun 14, 2024 to now24
- Board memberAngela Thedinga Mar 29, 2022 to now25
- Board memberPeter Kolchinsky Apr 28, 2022 to now26
- Board memberRajeev M. Shah Apr 28, 2022 to now26
- Board memberAli Behbahani Jul 9, 2020 to now27
- Board memberFouad Oscar Azzam Jul 9, 2020 to Jun 9, 202328
- Board memberLaura Shawver Jul 9, 2020 to Jun 10, 202229
- Board memberLeone D. Patterson Jul 9, 2020 to now30
- Board memberMichael Dybbs Jul 9, 2020 to now31
- Board memberPaul J. Hastings Jul 9, 2020 to now23
- Board memberPlc Glaxosmithkline Jul 9, 2020 to Jul 16, 202032
- Board memberSimeon George Jul 9, 2020 to now33
- Board memberTiba Aynechi Jul 9, 2020 to Jun 10, 202234
- Board memberZachary Scheiner Jul 9, 2020 to now35
- General counselAlicia J. Hager Oct 28, 2020 to now36
Timeline
Filings
288 filings to the SEC since October 2021: 5 annual reports, 15 quarterly reports, 48 major events, 137 insider forms, 44 large holders, 39 other. The latest 20:
- Aug 10, 202610-Q EDGAR
- Aug 10, 20268-K EDGAR
- Jun 22, 20264 EDGAR
- Jun 11, 20264 EDGAR
- Jun 11, 20268-K EDGAR
- Jun 11, 20264 EDGAR
- Jun 11, 20264 EDGAR
- Jun 11, 20264 EDGAR
- Jun 11, 20264 EDGAR
- Jun 11, 20264 EDGAR
- Jun 11, 20264 EDGAR
- Jun 11, 20264 EDGAR
- May 19, 2026SCHEDULE 13D/A EDGAR
- May 12, 202610-Q EDGAR
- May 12, 20268-K EDGAR
- Apr 23, 2026ARS EDGAR
- Apr 23, 2026DEFA14A EDGAR
- Apr 23, 2026DEF 14A EDGAR
- Apr 3, 2026EFFECT EDGAR
- Apr 3, 2026424B5 EDGAR
The 288 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
52 open-market trades by officers, directors and large owners since October 2021: 4 buys and 48 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Jun 18, 2026 | HASTINGS PAUL JChief Executive Officer | Sale | 1,776 | $2.71 | $4.8K | Form 4 |
| Jan 15, 2026 | HASTINGS PAUL JChief Executive Officer | Sale | 26,046 | $2.07 | $53.9K | Form 4 |
| Jan 15, 2026 | Mahmood NadirPresident | Sale | 5,649 | $2.07 | $11.7K | Form 4 |
| Jun 18, 2025 | HASTINGS PAUL JChief Executive Officer | Sale | 1,790 | $1.79 | $3.2K | Form 4 |
| Jan 15, 2025 | Shook DavidSee Remarks | Sale | 8,638 | $2.20 | $19.0K | Form 4 |
| Jan 15, 2025 | Levin AlyssaSee Remarks | Sale | 5,838 | $2.20 | $12.8K | Form 4 |
| Jan 15, 2025 | Brandenberger RalphChief Technical Officer | Sale | 7,447 | $2.20 | $16.4K | Form 4 |
| Jan 15, 2025 | HASTINGS PAUL JChief Executive Officer | Sale | 17,378 | $2.20 | $38.2K | Form 4 |
| Jan 15, 2025 | Hager Alicia J.Chief Legal Officer | Sale | 9,584 | $2.20 | $21.1K | Form 4 |
| Jul 16, 2024 | Hager Alicia J.Chief Legal Officer | Sale | 3,396 | $8.00 | $27.2K | Form 4 |
| Jun 18, 2024 | Trager JamesChief Scientific Officer | Sale | 456 | $5.60 | $2.6K | Form 4 |
| Jun 18, 2024 | HASTINGS PAUL JChief Executive Officer | Sale | 1,770 | $5.60 | $9.9K | Form 4 |
| Jun 18, 2024 | Shook DavidSee Remarks | Sale | 456 | $5.60 | $2.6K | Form 4 |
| Jun 18, 2024 | Hager Alicia J.Chief Legal Officer | Sale | 727 | $5.60 | $4.1K | Form 4 |
| Jun 18, 2024 | Brandenberger RalphChief Technical Officer | Sale | 229 | $5.60 | $1.3K | Form 4 |
| Mar 27, 2024 | RA CAPITAL MANAGEMENT, L.P.Director | Buy | 3,000,000 | $10.00 | $30.0M | Form 4 |
| Mar 27, 2024 | George SimeonDirector | Buy | 2,000,000 | $10.00 | $20.0M | Form 4 |
| Mar 1, 2024 | Brandenberger RalphChief Technical Officer | Sale | 8,367 | $12.51 | $104.7K | Form 4 |
| Feb 12, 2024 | Trager JamesChief Scientific Officer | Sale | 4,143 | $12.00 | $49.7K | Form 4 |
| Jan 16, 2024 | Shook DavidSee Remarks | Sale | 3,552 | $8.74 | $31.0K | Form 4 |
All 52 trades can be filtered by person here when JavaScript is on.
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
- New Enterprise Associates 15, L.P.SCHEDULE 13D/A, 3 filings May 5, 2022 to May 19, 202637
- TANG CAPITAL MANAGEMENT LLCSCHEDULE 13G/A, 2 filings Jan 27, 2025 to Feb 17, 202638
- Samsara BioCapital, L.P.SCHEDULE 13D/A, 3 filings Feb 14, 2023 to Nov 24, 202539
- CITADEL ADVISORS LLCSCHEDULE 13G/A, 2 filings Dec 13, 2024 to Nov 14, 202540
- BlackRockSCHEDULE 13G/A, 3 filings Oct 24, 2024 to Oct 17, 202541
- Commodore Capital LPSCHEDULE 13G/A, 3 filings Oct 27, 2023 to Feb 14, 202542
- ADAGE CAPITAL PARTNERS GP, L.L.C.SCHEDULE 13G/A, 3 filings Nov 3, 2023 to Feb 12, 202543
- LSP 6 Holding C.V.SCHEDULE 13D/A, 2 filings Feb 9, 2024 to Feb 12, 202544
- James E. FlynnSC 13G/A, 2 filings Oct 26, 2023 to Nov 14, 202445
- Adage Capital Management, L.P.SC 13G/A, 1 filing Nov 12, 202446
- Boxer Capital Management, LLCSC 13G/A, 1 filing Oct 25, 202447
- RA CAPITAL MANAGEMENT, L.P.SC 13D/A, 2 filings May 2, 2022 to Mar 29, 202448
- Boxer Capital, LLCSC 13G, 1 filing Jan 18, 202449
- T. Rowe Price Investment Management, Inc.SC 13G/A, 3 filings Feb 10, 2023 to Nov 13, 202350
- WASATCH ADVISORS LPSC 13G/A, 3 filings Feb 9, 2023 to Oct 10, 202351
- Deep Track Capital, LPSC 13G/A, 2 filings Feb 18, 2022 to Feb 14, 202352
- Novo Holdings A/SSC 13D/A, 3 filings Nov 22, 2021 to Jun 3, 202253
- Logos Global Management LPSC 13G/A, 1 filing Feb 14, 202254
Held by these funds
The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.
| Fund | Shares | Value | Share of the fund | Change |
|---|---|---|---|---|
| Ra Capital Management, L.P. | 10,805,129 | $30.6M | 0.3% | No change |
| BlackRock, Inc. | 6,300,212 | $17.8M | 0.0% | +1,791,739 |
| NEA Management Company, LLC | 3,568,781 | $10.1M | 0.6% | No change |
| Samsara Biocapital, LLC | 3,507,666 | $9.9M | 0.8% | No change |
| SR One Capital Management, LP | 3,333,333 | $9.4M | 0.9% | No change |
| GSK plc | 3,150,732 | $8.9M | 1.5% | No change |
| Monaco Asset Management SAM | 2,373,400 | $6.7M | 2.5% | −148,532 |
| Vanguard Capital Management LLC | 2,226,415 | $6.3M | 0.0% | +214,994 |
| Citadel Advisors LLC | 2,174,745 | $6.2M | 0.0% | +390,751 |
| Two Sigma Investments, LP | 1,873,293 | $5.3M | 0.0% | −174,083 |
| Wasatch Advisors LP | 1,577,847 | $4.5M | 0.0% | No change |
| State Street Corp | 1,286,109 | $3.6M | 0.0% | +48,635 |
| Geode Capital Management, LLC | 1,285,507 | $3.6M | 0.0% | +17,592 |
| Renaissance Technologies LLC | 1,177,652 | $3.3M | 0.0% | −554,720 |
| Aqr Capital Management LLC | 1,054,251 | $3.0M | 0.0% | +458,525 |
| AWM Investment Company, Inc. | 906,000 | $2.6M | 0.2% | No change |
| Blackstone Inc. | 747,044 | $2.1M | 0.0% | New |
| Marshall Wace, Llp | 673,010 | $1.9M | 0.0% | New |
| Panagora Asset Management Inc | 583,249 | $1.7M | 0.0% | +299,039 |
| Jpmorgan Chase & Co | 562,980 | $1.6M | 0.0% | −12,021 |
| Peapod Lane Capital LLC | 549,923 | $1.6M | 1.1% | −126,289 |
| Alyeska Investment Group, L.P. | 484,840 | $1.4M | 0.0% | −1,600,000 |
| Dimensional Fund Advisors LP | 483,211 | $1.4M | 0.0% | +136,618 |
| Nuveen, LLC | 469,555 | $1.3M | 0.0% | +23,757 |
| Goldman Sachs Group Inc | 433,982 | $1.2M | 0.0% | +48,982 |
13F reports cover disclosed long positions in U.S. stocks only.
Links
- Websitewww.nkartatx.com1
- X (Twitter)x.com/nkartatx1
- LinkedInwww.linkedin.com/company/nkarta-inc1
- WikidataQ107518637
- SEC EDGARCIK 1787400
Sources
The numbers on this page point here. Each one links to the record it came from.
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- 14SEC EDGARNadir Mahmood, President
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- 16SEC EDGARShawn Marshall Rose, Officer
- 17SEC EDGARDavid Shook, Chief Medical Officer
- 18SEC EDGARAlyssa Levin, Officer
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- 23SEC EDGARPaul J. Hastings, Officer
- 24SEC EDGARGeorge Vratsanos, Board member
- 25SEC EDGARAngela Thedinga, Board member
- 26SEC EDGARPeter Kolchinsky, Board member
- 27SEC EDGARAli Behbahani, Board member
- 28SEC EDGARFouad Oscar Azzam, Board member
- 29SEC EDGARLaura Shawver, Board member
- 30SEC EDGARLeone D. Patterson, Board member
- 31SEC EDGARMichael Dybbs, Board member
- 32SEC EDGARPlc Glaxosmithkline, Board member
- 33SEC EDGARSimeon George, Board member
- 34SEC EDGARTiba Aynechi, Board member
- 35SEC EDGARZachary Scheiner, Board member
- 36SEC EDGARAlicia J. Hager, General counsel
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