Private company

Regulus Therapeutics Inc.

The Regulus Therapeutics logo is a trademark of Regulus Therapeutics Inc. We use “Regulus Therapeutics” as a trademark in the United States and other countries.3 From its latest annual report

Last updated Oct 19, 2026.

Overview

  • IndustryPharmaceutical Preparations1
  • HeadquartersSan Diego, California1
  • Incorporated inDE2
  • Business address4224 Campus Point Court, Suite 210, San Diego, Ca 921212
  • Filer categoryNon-accelerated filer, Smaller reporting company2
  • Legal formCorporation

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The Regulus Therapeutics logo is a trademark of Regulus Therapeutics Inc. We use “Regulus Therapeutics” as a trademark in the United States and other countries. We have registered this trademark in the United States, the European Union ("EU") and Switzerland. All other product and company names are trademarks of their respective companies.3 From its latest annual report

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2021

-100.0%Revenue growth, 20214
-50.6%Return on equity5
0.09×Debt to equity6
-$24.4MFree cash flow6

Financial statements

Revenue784$0 in 2021
0$5.0M$10.0M$15.0M2018: $72.0K$72.0K20182019: $6.8M$6.8M2019+9389%2020: $10.0M$10.0M2020+46%2021: $0$02021
Operating income7846-$27.8M in 2021−41% since 2018
-$60.0M-$40.0M-$20.0M02018: -$46.8M-$46.8M20182019: -$16.8M-$16.8M2019−64%2020: -$14.2M-$14.2M2020−16%2021: -$27.8M-$27.8M2021+97%
Net income7846-$27.8M in 2021−43% since 2018
-$60.0M-$40.0M-$20.0M02018: -$48.7M-$48.7M20182019: -$18.6M-$18.6M2019−62%2020: -$15.7M-$15.7M2020−15%2021: -$27.8M-$27.8M2021+77%
Fiscal year2018201920202021
Revenue$72.0K7$6.8M8$10.0M4$04
Research and development$34.0M7$12.3M8$15.3M4$17.8M6
Operating expenses$27.8M6
Operating income-$46.8M7-$16.8M8-$14.2M4-$27.8M6
Interest$2.3M7$2.1M8$1.8M4$855.0K6
Income before tax-$27.8M6
Income tax$62.0K7$1.0K8$04$1.0K6
Net income-$48.7M7-$18.6M8-$15.7M4-$27.8M6
Earnings per share-$0.454$3.246
Earnings per share (diluted)-$0.454$3.246
Shares (weighted, basic)8.6M shares6
Shares (weighted, diluted)8.6M shares6

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Leadership

Who has led Regulus Therapeutics Inc., and when. Pick a name to see everywhere that person has worked.

Chief executive

  1. Kleanthis G. Xanthopoulos2012–2015
  2. Paul C. Grint2015–2017
  3. Joseph P. Hagan2017–now

President

  1. Kleanthis G. Xanthopoulos2012–2015
  2. Paul C. Grint2015–2017
  3. Joseph P. Hagan2017–2023
  4. Preston Klassen2023–now

Chief financial officer

  1. Daniel R. Chevallard2017–2019
  2. Crispina Calsada2019–now

Chief operating officer

  1. Garry E. Menzel2012
  2. Joseph P. Hagan2016–2017
201520202025
Board members and other officers (26)

Named in SEC Form D filings

People the company listed in its private-offering notices.

  • DirectorJake R. Nunn named Dec 6, 202143

Timeline

  1. May 8, 2017New chief executive Joseph P. Hagan becomes CEO12
  2. Jun 26, 2015New chief executive Paul C. Grint becomes CEO13
  3. Oct 4, 2012New chief executive Kleanthis G. Xanthopoulos becomes CEO14

Filings

277 filings to the SEC since October 2021: 5 annual reports, 11 quarterly reports, 37 major events, 110 insider forms, 30 large holders, 1 private raises, 83 other. The latest 20:

  1. Aug 14, 2025SCHEDULE 13G/A EDGAR
  2. Aug 14, 2025SCHEDULE 13G/A EDGAR
  3. Jul 7, 202515-12G EDGAR
  4. Jul 1, 2025EFFECT EDGAR
  5. Jul 1, 2025EFFECT EDGAR
  6. Jul 1, 2025EFFECT EDGAR
  7. Jul 1, 2025EFFECT EDGAR
  8. Jul 1, 2025EFFECT EDGAR
  9. Jul 1, 2025EFFECT EDGAR
  10. Jul 1, 2025EFFECT EDGAR
  11. Jul 1, 2025EFFECT EDGAR
  12. Jun 27, 20254 EDGAR
  13. Jun 27, 20254 EDGAR
  14. Jun 27, 20254 EDGAR
  15. Jun 27, 20254 EDGAR
  16. Jun 27, 20254 EDGAR
  17. Jun 27, 20254 EDGAR
  18. Jun 27, 20254 EDGAR
  19. Jun 27, 20254 EDGAR
  20. Jun 27, 20254 EDGAR

The 277 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

17 open-market trades by officers, directors and large owners since October 2021: 7 buys and 10 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Jun 3, 2025Klassen PrestonPresident & Head of R & DBuy12,000$7.99$95.9KForm 4
Jan 30, 2025Hagan Joseph PChief Executive OfficerBuy50,000$1.09$54.5KForm 4
Jan 30, 2025BALTIMORE DAVIDDirectorBuy19,610$1.06$20.8KForm 4
Jan 14, 2025Hagan Joseph PChief Executive OfficerSale11,764$1.26$14.8KForm 4
Jan 14, 2025Aker Christopher RaySr. VP & General CounselSale5,088$1.26$6.4KForm 4
Jan 14, 2025CALSADA CRISPINAChief Financial OfficerSale5,088$1.26$6.4KForm 4
Jan 13, 2025Hagan Joseph PChief Executive OfficerSale115,290$1.26$145.3KForm 4
Jan 13, 2025Aker Christopher RaySr. VP & General CounselSale38,547$1.26$48.6KForm 4
Jan 13, 2025CALSADA CRISPINAChief Financial OfficerSale38,716$1.26$48.8KForm 4
Jan 13, 2025Klassen PrestonPresident & Head of R & DSale31,445$1.26$39.6KForm 4
Jul 25, 2024Collier Kathryn JDirectorBuy4,000$1.82$7.3KForm 4
Jan 18, 2024CALSADA CRISPINAChief Financial OfficerSale5,468$1.19$6.5KForm 4
Jan 18, 2024Aker Christopher RaySr. VP & General CounselSale5,468$1.19$6.5KForm 4
Jan 18, 2024Hagan Joseph PChief Executive OfficerSale14,580$1.19$17.4KForm 4
Mar 1, 2022Drygin DenisChief Scientific OfficerBuy76,686$0.23$17.6KForm 4
Feb 4, 2022Drygin DenisChief Scientific OfficerBuy23,314$0.23$5.4KForm 4
Jan 26, 2022Hagan Joseph PChief Executive OfficerBuy100,000$0.22$22.0KForm 4

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Money raised

Private offerings the company reported to the SEC on Form D.

  1. Nov 30, 2021Raised $34.6 million in a private offering of equity Form D: 16 investors so far Form D

Sources

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