SCLX on Nasdaq

Scilex Holding Co

We are an innovative revenue-generating company focused on acquiring, developing and commercializing non-opioid pain management products for the treatment of acute and chronic pain.3 From its latest annual report

Price unavailable

Last updated Oct 19, 2026.

Overview

Compare with Scholar Rock Holding Corp, Precision BioSciences or X4 Pharmaceuticals, Inc, or pick any stock.

  • TickerSCLX on Nasdaq1
  • IndustryBiological Products, (No Diagnostic Substances)1
  • HeadquartersPalo Alto, California1
  • Incorporated inDE2
  • Business address960 San Antonio Road, Palo Alto, Ca 943032
  • Filer category, Emerging growth company2
  • Legal formCorporation

We are an innovative revenue-generating company focused on acquiring, developing and commercializing non-opioid pain management products for the treatment of acute and chronic pain. We target indications with high unmet needs and large market opportunities with non-opioid therapies for the treatment of patients with acute and chronic pain and are dedicated to advancing and improving patient outcomes.3 From its latest annual report

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

415.8%Gross margin4
-1143.7%Operating margin4
-1236.4%Net margin4
-46.5%Revenue growth, 20254
$3.7MFree cash flow4

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Cost of revenue4¢$10.6M
  • Research and development7¢$20.7M
  • Selling, general and admin89¢$266.9M
  • Income tax0¢$26.0K

Out of $30.3M in revenue.4 The company lost money this year.

Where each dollar of operating cash went, fiscal 2025

  • Capital spending3¢$133.0K
  • Kept or used elsewhere97¢$3.7M

Out of $3.8M of cash from operations.4

Financial statements

Revenue5674$30.3M in 2025+28% since 2020
0$20.0M$40.0M$60.0M2020: $23.6M$23.6M20202021: $31.3M$31.3M2021+33%2022: $38.0M$38.0M2022+21%2023: $46.7M$46.7M2023+23%2024: $56.6M$56.6M2024+21%2025: $30.3M$30.3M2025−47%
Gross profit4$125.8M in 2025−25% since 2024
0$50.0M$100.0M$150.0M$200.0M2024: $167.4M$167.4M20242025: $125.8M$125.8M2025−25%
Operating income5674-$346.0M in 2025+881% since 2020
-$400.0M-$300.0M-$200.0M-$100.0M02020: -$35.3M-$35.3M20202021: -$35.8M-$35.8M2021+2%2022: -$50.6M-$50.6M2022+41%2023: -$105.4M-$105.4M2023+108%2024: -$83.4M-$83.4M2024−21%2025: -$346.0M-$346.0M2025+315%
Net income5674-$374.1M in 2025+687% since 2020
-$400.0M-$300.0M-$200.0M-$100.0M02020: -$47.5M-$47.5M20202021: -$88.4M-$88.4M2021+86%2022: -$23.4M-$23.4M2022−74%2023: -$114.3M-$114.3M2023+389%2024: -$72.8M-$72.8M2024−36%2025: -$374.1M-$374.1M2025+414%

Every line of the income statement as filed: the last 2 fiscal years, latest first.4

Period ending2025-12-312024-12-31
Net Revenue$30.3M$56.6M
Cost of revenue$10.6M$16.7M
Research and development$20.7M$9.6M
Selling, general and administrative$266.9M$119.0M
Goodwill impairment$73.4M$0
Intangible amortization$4.4M$4.0M
Legal settlements$345.0K-$9.4M
Total net operating costs and expenses$376.3M$140.0M
Loss from operations-$346.0M-$83.4M
(Gain) loss on derivative liability$22.7M-$17.4M
Change in fair value of debt and liability instruments$25.4M$4.8M
Interest expense, net$11.5M$2.0M
Loss on foreign currency exchange-$86.0K$45.0K
Unrealized loss on digital assets, net$12.2M$0
Loss on debt extinguishment, net$7.4M$0
Realized loss on digital assets, net$30.2M$0
Unrealized (gain) on equity investment, net-$2.7M$0
Realized (gain) on equity investments, net-$19.2M$0
Unrealized (gain) on equity method investments carried at fair value, net-$54.8M$0
Realized (gain) on equity method investments carried at fair value, net-$4.7M$0
Realized (gain) on securities$199.0K$0
Total other (income) expense, net$28.0M-$10.6M
Loss before income taxes-$374.0M-$72.8M
Income tax expense (benefit)$26.0K-$1.0K
Net loss-$374.1M-$72.8M
Net Loss Attributable to Common Stockholders Before Deemed Dividend-$358.7M-$72.8M
Deemed dividend-$43.8M$0
Net loss attributable to noncontrolling interests-$15.3M$0
Net Income (Loss) Available to Common Stockholders, Basic, Total-$402.5M-$72.8M
Net comprehensive loss attributable to common stockholders-$358.7M-$72.8M
Net loss per share attributable to common stockholders - basic-$36.48-$7.24
Net loss per share attributable to common stockholders - diluted-$36.48-$8.05
Weighted average number of shares during the period-basic11.0K shares10.1K shares
Weighted average number of shares, diluted11.0K shares10.1K shares
Foreign currency translation adjustment-$756.0K$0
Changes in fair value attributable to instrument-specific credit risk-$11.4M$6.3M
Total other comprehensive income-$12.1M$6.3M
Comprehensive loss attributable to common stockholders-$370.9M-$66.5M

Compare Scilex Holding Co with another company

Leadership

Who has led Scilex Holding Co, and when. Pick a name to see everywhere that person has worked.

Board members and other officers (17)

Named in SEC Form D filings

People the company listed in its private-offering notices.

  • Executive Officer, DirectorStephen Ma named Oct 5, 2023 to Oct 14, 202526
  • Executive Officer, DirectorJaisim Shah named Oct 5, 202327

Former names

  • Scilex Holding Company/DEJun 9, 2022 to Nov 30, 20222
  • Vickers Vantage Corp. IAug 19, 2020 to Nov 15, 20222

Timeline

  1. Oct 9, 2025New chief executive Henry Ji becomes CEO11

Filings

703 filings to the SEC since October 2021: 6 annual reports, 16 quarterly reports, 144 major events, 80 insider forms, 33 large holders, 2 private raises, 422 other. The latest 20:

  1. Sep 29, 20268-K EDGAR
  2. Aug 24, 2026SCHEDULE 13D/A EDGAR
  3. Aug 14, 202610-Q EDGAR
  4. Aug 12, 20268-K EDGAR
  5. Jul 22, 20268-K EDGAR
  6. Jul 7, 2026SCHEDULE 13D/A EDGAR
  7. Jul 7, 20264 EDGAR
  8. Jul 6, 20268-K EDGAR
  9. Jun 30, 2026S-8 EDGAR
  10. Jun 29, 20268-K EDGAR
  11. Jun 24, 20268-K EDGAR
  12. Jun 11, 2026EFFECT EDGAR
  13. Jun 9, 2026CORRESP EDGAR
  14. Jun 9, 2026UPLOAD EDGAR
  15. Jun 2, 2026S-3 EDGAR
  16. May 22, 2026EFFECT EDGAR
  17. May 20, 2026CORRESP EDGAR
  18. May 20, 202610-Q EDGAR
  19. May 15, 2026NT 10-Q EDGAR
  20. May 11, 20268-K EDGAR

The 703 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

19 open-market trades by officers, directors and large owners since October 2021: 15 buys and 4 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Dec 30, 2025Scilex Holding Co10% ownerSale9,657,300$0.54$5.2MForm 4
Dec 29, 2025Scilex Holding Co10% ownerSale7,310,984$0.66$4.8MForm 4
Dec 26, 2025Scilex Holding Co10% ownerSale3,689,016$0.75$2.8MForm 4
Dec 18, 2024SHAH JAISIMSee RemarksBuy30,000$0.46$13.8KForm 4
Oct 31, 2024Ji HenryExec Chair, CEO and PresidentBuy8,888$0.94$8.4KForm 4
Oct 29, 2024SHAH JAISIMSee RemarksBuy32,000$0.99$31.7KForm 4
Oct 18, 2024Followwill DormanDirectorBuy1,000$0.99$990Form 4
Oct 18, 2024Chun JayDirectorBuy5,000$0.95$4.8KForm 4
Oct 17, 2024Wu Yue AlexanderDirectorBuy20,000$0.95$19.0KForm 4
Oct 17, 2024Lemus DavidDirectorBuy2,000$0.90$1.8KForm 4
Oct 17, 2024Ji HenryExec Chair, CEO and PresidentBuy10,000$0.97$9.7KForm 4
Oct 16, 2024SHAH JAISIMSee RemarksBuy30,000$0.99$29.7KForm 4
Oct 16, 2024Ma Stephen HoiCFO, COO and SecretaryBuy6,700$0.97$6.5KForm 4
May 17, 2024Ji HenryExec Chair, CEO and PresidentBuy50,000$0.88$44.0KForm 4
May 17, 2024Chun JayDirectorBuy57,500$0.90$51.8KForm 4
May 17, 2024SHAH JAISIMSee RemarksBuy56,939$0.92$52.4KForm 4
May 17, 2024Ma Stephen HoiCFO, COO and SecretaryBuy14,140$0.88$12.4KForm 4
May 16, 2024SHAH JAISIMSee RemarksBuy83,061$0.84$69.8KForm 4
Sep 21, 2023Sorrento Therapeutics, Inc.10% ownerSale60,068,585Form 4

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Money raised

Private offerings the company reported to the SEC on Form D.

  1. Sep 30, 2025Raised $2.7 million in a private offering of securities Form D: 2 investors so far Form D
  2. Sep 21, 2023Raised $101.9 million in a private offering of debt Form D: 1 investor so far Form D

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 70. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
Vanguard Capital Management LLC301,292$2.4M0.0%+37,242
BlackRock, Inc.109,417$853.5K0.0%+6,621
Vanguard Fiduciary Trust Co45,822$357.4K0.0%+6,164
Jacobs Levy Equity Management, Inc41,163$321.1K0.0%New
State Street Corp35,376$275.9K0.0%No change
UBS Group AG33,376$260.3K0.0%+26,908
Renaissance Technologies LLC33,064$257.9K0.0%−3,800
Citadel Advisors LLC27,497$214.5K0.0%New
Ashton Thomas Private Wealth, LLC18,482$144.2K0.0%+493
Northern Trust Corp15,047$117.4K0.0%+14
Morgan Stanley4,032$31.5K0.0%−7,941
Vanguard Global Advisers, LLC2,937$22.9K0.0%No change
Osaic Holdings, Inc.2,339$18.2K0.0%+2,241
Creative Financial Designs Inc /adv1,853$14.5K0.0%No change
Royal Bank Of Canada1,745$14.0K0.0%+149
Jones Financial Companies Lllp1,755$12.5K0.0%+1,003
Larson Financial Group LLC1,419$11.1K0.0%+1,377
MetLife Investment Management, LLC1,090$8.5K0.0%No change
Deutsche Bank Ag\800$6.2K0.0%No change
Versant Capital Management, Inc761$5.9K0.0%No change
IFP Advisors, Inc576$4.5K0.0%No change
MCF Advisors LLC474$3.7K0.0%No change
Activest Wealth Management302$2.4K0.0%No change
Klp Kapitalforvaltning As290$2.3K0.0%No change
Integrated Wealth Concepts LLC149$1.2K0.0%New

13F reports cover disclosed long positions in U.S. stocks only.

Sources

The numbers on this page point here. Each one links to the record it came from.

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9
  10. 10
  11. 11
  12. 12
  13. 13
  14. 14
  15. 15
  16. 16
  17. 17
  18. 18
  19. 19
  20. 20
  21. 21
  22. 22
  23. 23
  24. 24
  25. 25
  26. 26
  27. 27
  28. 28
  29. 29
  30. 30
  31. 31
  32. 32
  33. 33
  34. 34
  35. 35