TRVN on NASDAQ

Trevena Inc

Logo: Trevena, Public domain, via Wikimedia Commons5

American biopharmaceutical company

Trevena, Inc. is a clinical stage biopharmaceutical company, headquartered in Chesterbrook, Pennsylvania, USA, and is involved in the discovery and development of G-protein coupled receptors (GPCR) biased ligands.3 From Wikipedia, CC BY-SA 4.0

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Last updated Oct 19, 2026.

Overview

2007Founded1

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  • TickerTRVN on NASDAQ1
  • Industrypharmaceutical industry1
  • HeadquartersKing of Prussia1
  • Websitewww.trevena.com
  • Legal formDelaware corporation1
  • Business address2870 Peachtree Road, Suite 502, Atlanta, Ga 303056
  • Filer categoryNon-accelerated filer, Smaller reporting company6
  • LEI549300YXUV4MU2J7QS074
  • StatusActive4
  • LEI statusLapsed (not renewed)4
  • Registered addressC/O Corporation Service Company, 19808 Wilmington, United States4

Trevena, Inc. is a clinical stage biopharmaceutical company, headquartered in Chesterbrook, Pennsylvania, USA, and is involved in the discovery and development of G-protein coupled receptors (GPCR) biased ligands. Trevena was founded in 2007 with technology licensed from Duke University, which originated in the labs of company founders Robert Lefkowitz winner of the 2012 Nobel Prize in Chemistry and Howard Rockman. Trevena's approach to drug discovery is based on utilizing ligand bias, or functional selectivity, at GPCR targets to produce drugs with improved efficacy and reduced side effect profiles. Trevena was named one of the top 15 US startups of 2008 by Business Week.3

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2021

-9157.8%Operating margin8
-9098.4%Net margin8
-81.5%Revenue growth, 20219
-79.8%Return on equity10
-$50.2MFree cash flow8

Where the money goes

Where each dollar of revenue went, fiscal 2021

  • Cost of revenue7¢$954.0K
  • Research and development93¢$13.4M
  • Interest0¢$1.0K

Out of $567.0K in revenue.98 The company lost money this year.

Financial statements

Revenue1112139$567.0K in 2021
0$2.0M$4.0M$6.0M2017: $0$020172018: $5.7M$5.7M20182019: $31.0K$31.0K2019−99%2020: $3.1M$3.1M2020+9800%2021: $567.0K$567.0K2021−82%
Operating income121398-$51.9M in 2021−26% since 2017
-$80.0M-$60.0M-$40.0M-$20.0M02017: -$70.4M-$70.4M20172018: -$30.5M-$30.5M2018−57%2019: -$26.6M-$26.6M2019−13%2020: -$29.5M-$29.5M2020+11%2021: -$51.9M-$51.9M2021+76%
Net income121398-$51.6M in 2021−28% since 2017
-$80.0M-$60.0M-$40.0M-$20.0M02017: -$71.9M-$71.9M20172018: -$30.8M-$30.8M2018−57%2019: -$24.9M-$24.9M2019−19%2020: -$29.4M-$29.4M2020+18%2021: -$51.6M-$51.6M2021+76%
Fiscal year20172018201920202021
Revenue$011$5.7M12$31.0K13$3.1M9$567.0K9
Cost of revenue$182.0K9$954.0K8
Research and development$49.0M12$15.8M12$13.3M13$13.1M9$13.4M8
Operating expenses$52.5M8
Operating income-$70.4M12-$30.5M12-$26.6M13-$29.5M9-$51.9M8
Interest$2.8M12$2.2M12$931.0K13$29.0K9$1.0K8
Income before tax-$51.6M9
Income tax$745.0K12$300.0K9
Net income-$71.9M12-$30.8M12-$24.9M13-$29.4M9-$51.6M8
Earnings per share-$0.239-$7.908
Earnings per share (diluted)-$0.239-$7.908
Shares (weighted, basic)6.5M shares8
Shares (weighted, diluted)6.5M shares8

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The story

In 2008, the company raised $25 Million in a Series A financing round led by Alta Partners, Polaris Ventures, New Enterprise Associates, Healthcare Ventures, and Yasuda Economic Development Corporation.

In early 2009, Trevena entered into a collaborative agreement with Ligand Pharmaceuticals to identify biased ligands at numerous GPCRs from a large, diverse chemical library. Later that year, Trevena received a competitively awarded American Recovery and Reinvestment Act Grand Opportunities Grant, spanning two years and funding US$7.65 million of research. The company has disclosed specific interests in the mu Opioid receptor and kappa Opioid receptor. The company raised an additional US$35 million in a B round of venture financing in the summer of 2010. In 2011, Treveva received another NIH grant as part of the NIH Blueprint Neurotherapeutics Network, potentially worth up to $10M USD, to support preclinical development of a delta opioid receptor biased ligand for major depressive disorder. Trevena has received funding from the Michael J. Fox Foundation to explore the potential for delta opioid receptor biased ligands to treat Parkinson's disease.

Trevena's initial public offering was on January 30, 2014.

From Wikipedia’s article on Trevena, Inc., shared under CC BY-SA 4.0.7

Leadership

Who has led Trevena Inc, and when. Pick a name to see everywhere that person has worked.

Board members and other officers (30)

Timeline

  1. Oct 1, 2018New chief executive Carrie L. Bourdow becomes CEO17
  2. Jan 31, 2014Went public Listed on NASDAQ1
  3. Jan 30, 2014New chief executive Maxine Gowen becomes CEO18
  4. 2007Founded Founded1

Filings

202 filings to the SEC since October 2021: 3 annual reports, 10 quarterly reports, 63 major events, 73 insider forms, 5 large holders, 48 other. The latest 20:

  1. Aug 14, 2026SCHEDULE 13G EDGAR
  2. Jan 14, 20268-K EDGAR
  3. May 15, 20258-K EDGAR
  4. Mar 31, 2025NT 10-K EDGAR
  5. Feb 3, 20258-K EDGAR
  6. Jan 15, 20258-K EDGAR
  7. Dec 6, 20243 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES EDGAR
  8. Nov 29, 2024RW EDGAR
  9. Nov 27, 20248-K EDGAR
  10. Nov 14, 2024SC 13G/A EDGAR
  11. Nov 7, 202410-Q EDGAR
  12. Nov 7, 20248-K EDGAR
  13. Oct 10, 20248-K EDGAR
  14. Oct 10, 20244 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES EDGAR
  15. Oct 10, 20244 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES EDGAR
  16. Oct 10, 20244 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES EDGAR
  17. Oct 4, 20248-K EDGAR
  18. Sep 19, 2024SC 13G EDGAR
  19. Sep 17, 20244 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES EDGAR
  20. Sep 17, 20244 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES EDGAR

The 202 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

1 open-market trades by officers, directors and large owners since October 2021: 0 buys and 1 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Jun 28, 2022Shin BarryActing COO and CFOSale31,785$0.41$13.0KForm 4

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Sources

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