TXG on Nasdaq

10X Genomics

Logo: 10x Genomics, Public domain, via Wikimedia Commons5

American biotechnology company

10x Genomics, Inc. is an American biotechnology company that designs and manufactures sequencing technologies for use in scientific research, with a focus on product development for single-cell and spatial omics.3 Its shares trade on Nasdaq under the symbol TXG.1 Wikipedia text CC BY-SA 4.0

Price unavailable

Last updated Oct 20, 2026.

Overview

$642.8MRevenue, fiscal 20256
-$43.5MNet income, fiscal 20256
2012Founded1

Compare with Cytek Biosciences, Inc., Pacific Biosciences or Bio-Rad Laboratories, or pick any stock.

  • TickerTXG on Nasdaq1
  • Industrybiotechnology industry1
  • HeadquartersPleasanton1
  • Websitewww.10xgenomics.com
  • Incorporated inDE7
  • Business address6230 Stoneridge Mall Road, Pleasanton, Ca 945887
  • Filer categoryLarge accelerated filer7
  • Legal formCorporation4
  • LEI5493003Z6741WNLG7H434
  • StatusActive4
  • LEI statusIssued and current4
  • Registered addressc/o NATIONAL REGISTERED AGENTS, INC., 1209 ORANGE STREET, 19801 Wilmington, United States4
  • Registered withDivision of Corporations, Department of State, 51786704

10x Genomics, Inc. is an American biotechnology company that designs and manufactures sequencing technologies for use in scientific research, with a focus on product development for single-cell and spatial omics.3

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

69.1%Gross margin6
-9.5%Operating margin6
-6.8%Net margin6
5.2%Revenue growth, 20256
-5.5%Return on equity6
$130.1MFree cash flow6

What sells

Revenue by product, business segment and region, as the company reports it to the SEC.

Products and services

Product and Service Revenue brought in 49% of the revenue 10X Genomics broke down this way in fiscal 2025.

  1. Product and Service Revenue$596.7M649%down 2% from 2024
  2. Single Cell Consumables$363.2M630%down 2% from 2024
  3. Spatial - Consumables$144.0M612%up 19% from 2024
  4. Licensing And Royalty Revenue$46.1M64%up 14272% from 2024
  5. Spatial - Instruments$34.1M63%down 41% from 2024
  6. Single Cell - Instruments$22.7M62%down 36% from 2024
Products and services by year
Products and services202320242025
Product and Service Revenue$618.7M$610.5M$596.7M
Single Cell Consumables$420.3M$372.3M$363.2M
Spatial - Consumables$59.2M$121.1M$144.0M
Licensing And Royalty Revenue$0$321.0K$46.1M
Spatial - Instruments$75.6M$57.5M$34.1M
Single Cell - Instruments$47.9M$35.2M$22.7M

Regions

United States brought in 54% of the revenue 10X Genomics broke down this way in fiscal 2025.

  1. United States$346.5M654%up 4% from 2024
  2. EMEA$161.7M625%up 1% from 2024
  3. China$70.3M611%up 23% from 2024
  4. Asia Pacific Excluding China$52.1M68%up 13% from 2024
  5. Americas (Excluding United States)$12.3M62%down 9% from 2024
Regions by year
Regions202320242025
United States$360.1M$334.3M$346.5M
EMEA$142.3M$159.8M$161.7M
China$51.0M$57.3M$70.3M
Asia Pacific Excluding China$52.3M$46.0M$52.1M
Americas (Excluding United States)$13.1M$13.4M$12.3M

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Cost of revenue31¢$198.9M
  • Selling, general and admin49¢$316.1M
  • Other costs19¢$124.1M
  • Income tax1¢$3.6M

Out of $642.8M in revenue.6 The company lost money this year.

Where each dollar of operating cash went, fiscal 2025

  • Capital spending4¢$5.9M
  • Kept or used elsewhere96¢$130.1M

Out of $136.1M of cash from operations.6

Financial statements

Revenue9101112136$642.8M in 2025+339% since 2018
0$200.0M$400.0M$600.0M$800.0M2018: $146.3M$146.3M20182019: $245.9M$245.9M2019+68%2020: $298.8M$298.8M2020+22%2021: $490.5M$490.5M2021+64%2022: $516.4M$516.4M2022+5%2023: $618.7M$618.7M2023+20%2024: $610.8M$610.8M2024−1%2025: $642.8M$642.8M2025+5%
Gross profit9101112136$443.9M in 2025+277% since 2018
0$200.0M$400.0M$600.0M2018: $117.7M$117.7M20182019: $184.9M$184.9M2019+57%2020: $240.4M$240.4M2020+30%2021: $416.4M$416.4M2021+73%2022: $396.0M$396.0M2022−5%2023: $409.3M$409.3M2023+3%2024: $414.5M$414.5M2024+1%2025: $443.9M$443.9M2025+7%
Operating income9101112136-$61.0M in 2025−45% since 2018
-$600.0M-$400.0M-$200.0M02018: -$110.8M-$110.8M20182019: -$30.6M-$30.6M2019−72%2020: -$534.1M-$534.1M2020+1647%2021: -$52.3M-$52.3M2021−90%2022: -$167.9M-$167.9M2022+221%2023: -$265.3M-$265.3M2023+58%2024: -$194.6M-$194.6M2024−27%2025: -$61.0M-$61.0M2025−69%
Net income9101112136-$43.5M in 2025−61% since 2018
-$600.0M-$400.0M-$200.0M02018: -$112.5M-$112.5M20182019: -$31.3M-$31.3M2019−72%2020: -$542.7M-$542.7M2020+1637%2021: -$58.2M-$58.2M2021−89%2022: -$166.0M-$166.0M2022+185%2023: -$255.1M-$255.1M2023+54%2024: -$182.6M-$182.6M2024−28%2025: -$43.5M-$43.5M2025−76%

Every line of the income statement as filed: the last 3 fiscal years, latest first.6

Period ending2025-12-312024-12-312023-12-31
Revenue$642.8M$610.8M$618.7M
Cost of products and services revenue$198.9M$196.3M$209.4M
Gross profit$443.9M$414.5M$409.3M
Research and development$238.6M$264.7M$270.3M
Selling, general and administrative$316.1M$344.3M$343.3M
Gain on settlement-$49.9M$0$0
In-process research and development$0$0$61.0M
Total operating expenses$504.9M$609.0M$674.6M
Loss from operations-$61.0M-$194.6M-$265.3M
Interest income$20.0M$18.9M$16.9M
Interest expense$0-$4.0K-$33.0K
Other income (expense), net$1.0M-$2.1M-$286.0K
Total other income$21.1M$16.9M$16.6M
Loss before provision for income taxes-$39.9M-$177.7M-$248.8M
Provision for income taxes$3.6M$4.9M$6.3M
Net loss-$43.5M-$182.6M-$255.1M
Net loss per share, basic (in dollars per share)-$0.35-$1.52-$2.18
Net loss per share, diluted (in dollars per share)-$0.35-$1.52-$2.18
Weighted-average shares used to compute net loss per share, basic (in shares)124.7M shares120.5M shares117.2M shares
Weighted-average shares used to compute net loss per share, diluted (in shares)124.7M shares120.5M shares117.2M shares

Compare 10X Genomics with another company

Corporate structure

10X Genomics sits at the top of its group. 1 entity, 1 country on record. Switch between the flow chart and the network, and select any entity to see its details.

Major holders of 10X Genomics

  • ARK Investment Management LLC Filed SCHEDULE 13G/A on 10X Genomics, latest Oct 7, 2026 (5 filings since Aug 12, 2024)
  • PRICE T ROWE ASSOCIATES INC /MD/ Filed SCHEDULE 13G on 10X Genomics, latest Sep 8, 2026
  • VANGUARD CAPITAL MANAGEMENT LLC Filed SCHEDULE 13G on 10X Genomics, latest Apr 29, 2026
  • VANGUARD PORTFOLIO MANAGEMENT LLC Filed SCHEDULE 13G on 10X Genomics, latest Apr 28, 2026
  • VANGUARD GROUP INC Filed SCHEDULE 13G/A on 10X Genomics, latest Mar 25, 2026 (7 filings since Feb 9, 2022)
  • FMR LLC Filed SCHEDULE 13G/A on 10X Genomics, latest Mar 6, 2026 (12 filings since Dec 10, 2021)
  • Amova Asset Management Americas, Inc. Filed SCHEDULE 13G/A on 10X Genomics, latest Nov 13, 2025 (4 filings since Nov 8, 2024)
  • Sumitomo Mitsui Trust Group Filed SCHEDULE 13G/A on 10X Genomics, latest Oct 27, 2025 (4 filings since Nov 5, 2024)
  • MILLENNIUM MANAGEMENT LLC Filed SCHEDULE 13G/A on 10X Genomics, latest Aug 12, 2025 (2 filings since Apr 4, 2025)
  • BAILLIE GIFFORD & CO Filed SC 13G/A on 10X Genomics, latest Jun 7, 2024 (4 filings since Jan 18, 2022)
  • Morgan Stanley Filed SC 13G/A on 10X Genomics, latest Dec 8, 2023 (5 filings since Feb 9, 2022)
  • Venrock Associates VI, L.P. Filed SC 13G/A on 10X Genomics, latest Feb 14, 2023 (2 filings since Feb 14, 2022)
  • 10X Genomics Pleasanton, California, United States

Built from parent and subsidiary links from GLEIF, the Global Legal Entity Identifier Foundation (CC0); major holders from Schedules 13D and 13G. Each entity in the chart links to its source.

What it owns

What 10X Genomics reports owning in its annual reports to the SEC: buildings, land and equipment, real estate and locations, investments, intangible assets and inventory, at the end of its latest fiscal year and a year before.

Property and equipment

ItemLatestA year beforeChange
Property and equipment, before depreciation$380.2M6 Dec 31, 2025$375.6M6 Dec 31, 2024+1.2%
Accumulated depreciation$153.5M6 Dec 31, 2025$123.0M6 Dec 31, 2024+24.8%
Property and equipment, net$226.7M6 Dec 31, 2025$252.6M6 Dec 31, 2024−10.3%
Operating-lease assets (leased space)$60.5M6 Dec 31, 2025$57.3M6 Dec 31, 2024+5.5%

Investments

ItemLatestA year beforeChange
Cash and cash equivalents$344.1M13 Dec 31, 2024$359.3M13 Dec 31, 2023−4.2%
Marketable securities, current$49.4M6 Dec 31, 2025$49.3M6 Dec 31, 2024+0.2%

Intangibles and goodwill

ItemLatestA year beforeChange
Goodwill$4.5M6 Dec 31, 2025$4.5M6 Dec 31, 20240%
Intangible assets, net (excluding goodwill)$62.3M6 Dec 31, 2025$15.7M6 Dec 31, 2024+297.7%
Finite-lived intangibles, gross$77.4M6 Dec 31, 2025$25.8M6 Dec 31, 2024+200.3%
Accumulated amortization$15.1M6 Dec 31, 2025$10.1M6 Dec 31, 2024+49.3%
Finite-lived intangibles, net$62.3M6 Dec 31, 2025$15.7M6 Dec 31, 2024+297.7%

Inventory

ItemLatestA year beforeChange
Inventory, total$56.3M6 Dec 31, 2025$83.1M6 Dec 31, 2024−32.2%
Work in process$17.1M6 Dec 31, 2025$27.4M6 Dec 31, 2024−37.6%
Finished goods$23.2M6 Dec 31, 2025$16.7M6 Dec 31, 2024+38.5%

Properties, in its own words

Our global corporate headquarters, research and development facilities, and manufacturing and distribution centers are located in Pleasanton, California, where we own approximately 148,000 square feet of space and lease approximately 300,000 square feet of space under leases expiring between September 2029 and June 2033, as well as a manufacturing and distribution center in Singapore and a manufacturing center in Taiwan. Including the Pleasanton leases, we lease approximately 431,000 square feet globally. We believe that our current and planned facilities are sufficient to meet our ongoing needs and that, if we require additional space, we will be able to obtain additional facilities on commercially reasonable terms.

Item 2 of the 10-K filed Feb 13, 2026.19

The story

10x Genomics was founded in 2012 by Serge Saxonov, Ben Hindson and Kevin Ness to create advanced testing equipment for use in cellular biology. Prior to starting the company, Saxonov was the founding architect, and director of research and development at 23andMe. Ness left 10x Genomics in December 2016 and in 2018, Justin McAnear, Tesla's former finance chief joined the company as CFO.

In August 2018, the company announced its first acquisition, Epinomics, a biotechnology company focused on the development of new techniques for epigenetics research. Four months later, 10x Genomics acquired Spatial Transcriptomics, a biotechnology company working in the field of spatial genomics. In November 2018, 10x Genomics announced expansion plans including opening a manufacturing facility in Pleasanton, California in early 2019.

10x Genomics announced its initial public offering on September 12, 2019, raising $390M. The company had revenues of $3.32 million in 2015, $27.48 million in 2016, $71.18 million in 2017, $145 million in 2018, and $618.7 million in 2023.

From Wikipedia’s article on 10x Genomics, shared under CC BY-SA 4.0.8

Leadership

Who has led 10X Genomics, and when. Pick a name to see everywhere that person has worked.

201520202025
Board members and other officers (14)

Timeline

  1. Aug 6, 20268-K Results of operations35
  2. Jun 8, 20268-K Shareholder vote36
  3. May 7, 20268-K Results of operations37
  4. Feb 12, 20268-K Results of operations38
  5. Jan 12, 20268-K Results of operations39
  6. Nov 14, 20258-K Executive or director change40
  7. Nov 6, 20258-K Results of operations41
  8. Aug 7, 20258-K Results of operations42
  9. Jun 5, 20258-K Shareholder vote43
  10. May 14, 20258-K Other events44
  11. May 8, 20258-K Results of operations; Exit or restructuring costs45
  12. Feb 12, 20258-K Results of operations46
  13. Sep 11, 2019New chief executive Serge Saxonov becomes CEO20
  14. 2012Founded Founded1

Filings

392 filings to the SEC since October 2021: 5 annual reports, 15 quarterly reports, 38 major events, 208 insider forms, 53 large holders, 73 other. The latest 20:

  1. Oct 7, 2026SCHEDULE 13G/A EDGAR
  2. Sep 24, 20264 EDGAR
  3. Sep 24, 20264 EDGAR
  4. Sep 22, 2026144 EDGAR
  5. Sep 11, 20264 EDGAR
  6. Sep 9, 2026144 EDGAR
  7. Sep 8, 20264 EDGAR
  8. Sep 8, 2026SCHEDULE 13G EDGAR
  9. Sep 3, 2026144 EDGAR
  10. Sep 3, 20264 EDGAR
  11. Aug 28, 20264 EDGAR
  12. Aug 26, 2026144 EDGAR
  13. Aug 26, 20264 EDGAR
  14. Aug 26, 20264 EDGAR
  15. Aug 26, 20264 EDGAR
  16. Aug 26, 20264 EDGAR
  17. Aug 24, 2026144 EDGAR
  18. Aug 24, 2026144 EDGAR
  19. Aug 24, 2026144 EDGAR
  20. Aug 24, 2026144 EDGAR

The 392 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last five years, summarized. The full record is on SEC EDGAR.

Insider trades

134 open-market trades by officers, directors and large owners since October 2021: 3 buys and 131 sales. Grants, option exercises and gifts are left out.

DateWhoTradeSharesPriceValueFiling
Sep 22, 2026SULIMAN SHEHNAAZDirectorSale5,723$81.19$464.7KForm 4
Sep 22, 2026Saxonov SergeChief Executive OfficerSale25,000$81.22$2.0MForm 4
Sep 9, 2026Taich AdamChief Financial OfficerSale46,388$64.58$3.0MForm 4
Sep 3, 2026STUELPNAGEL JOHN RDirectorSale20,000$61.76$1.2MForm 4
Aug 26, 2026Saxonov SergeChief Executive OfficerSale10,486$63.70$667.9KForm 4
Aug 24, 2026Saxonov SergeChief Executive OfficerSale18,545$63.02$1.2MForm 4
Aug 24, 2026Taich AdamChief Financial OfficerSale17,166$63.02$1.1MForm 4
Aug 24, 2026Hindson Benjamin J.See RemarksSale13,818$63.02$870.8KForm 4
Aug 24, 2026SULIMAN SHEHNAAZDirectorSale2,207$63.65$140.5KForm 4
Aug 14, 2026Teichmann Sarah A.DirectorSale2,273$57.15$129.9KForm 4
Aug 13, 2026Teichmann Sarah A.DirectorSale5,278$57.29$302.4KForm 4
Aug 11, 2026STUELPNAGEL JOHN RDirectorSale20,000$57.75$1.2MForm 4
Jun 22, 2026Saxonov SergeChief Executive OfficerSale30,000$34.44$1.0MForm 4
Jun 16, 2026SULIMAN SHEHNAAZDirectorSale5,723$32.63$186.8KForm 4
May 26, 2026Saxonov SergeChief Executive OfficerSale10,718$24.71$264.8KForm 4
May 22, 2026Saxonov SergeChief Executive OfficerSale18,175$24.44$444.2KForm 4
May 22, 2026Hindson Benjamin J.See RemarksSale11,595$24.44$283.4KForm 4
May 22, 2026Taich AdamChief Financial OfficerSale15,098$24.44$369.0KForm 4
Apr 14, 2026Saxonov SergeChief Executive OfficerSale5,000$24.56$122.8KForm 4
Mar 24, 2026Saxonov SergeChief Executive OfficerSale5,000$19.52$97.6KForm 4

All 134 trades can be filtered by person here when JavaScript is on.

From Forms 4 filed with the SEC.

Major holders

Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.

Executive pay

What the company paid its top executives, from the summary compensation table in its proxy statement. Total pay includes salary, bonus, stock and option awards and other pay, as the company valued them.

YearExecutiveAgeSalaryTotal pay
2025Serge SaxonovChief Executive Officer49$674.2K$6.3M59
2025Eric S. WhitakerFormer Chief Legal Officer$518.7K$3.4M59
2025Benjamin J. HindsonPresident and Chief Scientific Officer51$518.7K$2.6M59
2025Adam S. TaichChief Financial Officer51$507.5K$2.2M59
2024Serge SaxonovChief Executive Officer49$625.3K$7.9M59
2024Eric S. WhitakerFormer Chief Legal Officer$484.7K$7.0M59
2024Benjamin J. HindsonPresident and Chief Scientific Officer51$485.2K$4.3M59
2024Adam S. TaichChief Financial Officer51$192.3K$3.3M59
2023Serge SaxonovChief Executive Officer49$544.7K$8.3M59
2023Benjamin J. HindsonPresident and Chief Scientific Officer51$435.8K$4.4M59
2023Eric S. WhitakerFormer Chief Legal Officer$433.7K$3.9M59

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
Fmr LLC17,629,266$675.9M0.0%−111,706
BlackRock, Inc.10,804,070$414.2M0.0%+724,157
ARK Investment Management LLC10,003,057$383.5M2.5%−1,714,260
Vanguard Portfolio Management LLC6,982,492$267.7M0.0%+69,556
Quantinno Capital Management LP5,469,698$209.7M0.3%+57,937
Vanguard Capital Management LLC5,082,594$194.9M0.0%−186,992
Sumitomo Mitsui Trust Group, Inc.4,194,627$160.8M0.1%−915,587
Amova Asset Management Americas, Inc.4,192,517$160.7M2.1%−911,661
Morgan Stanley3,351,911$128.5M0.0%+695,558
Goldman Sachs Group Inc3,148,859$120.7M0.0%−822,941
Geode Capital Management, LLC3,082,790$118.2M0.0%+178,562
State Street Corp2,801,437$107.4M0.0%+212,642
Citadel Advisors LLC2,779,213$106.6M0.1%+2,035,479
Dimensional Fund Advisors LP2,225,284$85.3M0.0%+182,334
Jacobs Levy Equity Management, Inc2,019,883$77.4M0.3%−263,541
Aqr Capital Management LLC2,026,464$74.7M0.0%−511,792
Point72 Asset Management, L.P.1,852,776$71.0M0.1%New
Capital World Investors1,493,031$57.2M0.0%+40,731
Northern Trust Corp1,144,027$43.9M0.0%+96,022
Nuveen, LLC1,124,633$43.1M0.0%+498,837
Charles Schwab Investment Management Inc1,087,150$41.7M0.0%−39,906
Casdin Capital, LLC1,050,000$40.3M2.0%−1,225,000
Connor, Clark & Lunn Investment Management Ltd.988,320$37.9M0.1%+49,912
Bank Of America Corp /de/970,774$37.2M0.0%+6,195
Anomaly Capital Management, LP867,794$33.3M1.3%New

13F reports cover disclosed long positions in U.S. stocks only.

SEC filer profile

How 10X Genomics is registered with the Securities and Exchange Commission, from its EDGAR record and the cover page of its latest annual report.

  • Name on EDGAR10x Genomics, Inc.2
  • CIK0001770787
  • Employer ID (EIN)45-561445819
  • Filer statusLarge accelerated filer not an emerging growth company; not a smaller reporting company; not a shell company19
  • Incorporated inDelaware19
  • Fiscal year endsDecember 312
  • Industry code (SIC)3826 Laboratory Analytical Instruments2
  • SEC reviewing officeOffice of Industrial Applications and Services, Division of Corporation Finance2
  • Business address6230 Stoneridge Mall Road, Pleasanton, CA 945882
  • Phone(925) 401-73002
  • Shares outstanding117,673,382 Common Class A shares; 10,078,872 Common Class B shares as of Jan 31, 202619
  • Public float$1.3B as of Jun 30, 202519
  • AuditorErnst & Young LLP, San Jose, California PCAOB ID 42; it also attests to the company’s internal control over financial reporting19
  • On EDGAR sinceMay 9, 20192
  • Filings694 in all: 4 (386), 8-K (65), 144 (56), SC 13G/A (34), 10-Q (21), SCHEDULE 13G/A (20), 3 (19), SC 13G (14)2
    All 36 form types

    DEFA14A (8), 10-K (7), DEF 14A (7), S-8 (7), SCHEDULE 13G (6), UPLOAD (6), CORRESP (4), DRSLTR (4), 424B4 (2), DRS (2), DRS/A (2), EFFECT (2), S-1 (2), S-1/A (2), S-1MEF (2), SC 13D (2), SC 13D/A (2), SEC STAFF LETTER (2), 10-K/A (1), 4/A (1), 424B3 (1), 5 (1), 8-A12B (1), CERT (1), D (1), FWP (1), PRE 14A (1), S-3ASR (1)

  • Latest filingsAnnual report (10-K) Feb 13, 2026
    Quarterly report (10-Q) Aug 7, 2026
    Proxy statement (DEF 14A) Apr 24, 2026
    Latest 8-K (8-K) Aug 6, 2026

Securities registered for trading

ClassSymbolExchange
Class A common stock, par value $0.00001 per shareTXGThe Nasdaq Stock Market LLC

From the cover page of the 10-K filed Feb 13, 2026 (Section 12(b) of the Exchange Act).19

Risk factors and legal proceedings

The risks 10X Genomics names in Item 1A of its 10-K filed Feb 13, 2026: 72 risks under these headings, as written.19

  • Our operating results have in the past fluctuated significantly and may continue to fluctuate significantly in the future, which makes our future operating results difficult to predict and could cause our operating results to fall below expectations or any guidance we may provide.
  • Our business is significantly dependent on researchers and institutions which rely heavily on U.S. academic and government funding, including NIH grants, and any delays, reductions, modification of the terms or cancellations of such funding, or other changes to the budgets, budget cycles, seasonal or other spending patterns or the operations of our customers or the institutions that fund them, could adversely affect our sales and financial performance.
  • Our industry is highly competitive. If we fail to compete effectively, our business and operating results will suffer.
  • Price reductions, discounting or future price changes may negatively impact our financial results if we are unable to achieve offsetting benefits.
  • We may not be able to develop new products or new versions of existing products, enhance the capabilities of our existing products to keep pace with rapidly changing technology and customer requirements or successfully manage the transition to new product offerings, any of which could have a material adverse effect on our business and operating results.
  • Our failure to effectively manage product transitions or accurately forecast customer demand could result in excess or obsolete inventory and resulting charges.
  • Our business currently depends significantly on research and development spending by research institutions, a reduction in which could limit demand for our products and materially and adversely affect our business and operating results.
  • If we are unable to successfully execute our strategy to enter the clinical and diagnostic markets, our business and growth prospects could be materially and adversely affected.
  • Trade tariffs, import restrictions, export restrictions, Chinese regulations or other trade barriers may materially harm our business.
  • Our future success is dependent upon our ability to increase penetration in our existing customer segments.
  • Our past or future efforts to maintain and increase the effectiveness of our commercial organization may not succeed.
  • The size of the market for our solutions may be smaller than estimated and new opportunities may not develop as quickly as we expect, or at all, limiting our ability to successfully sell our solutions.
The other 60 risks
  • We have incurred significant losses since inception, we expect to incur losses in the future and we may not be able to generate sufficient revenue to achieve and maintain cash flows from operating activities in excess of our capital investment requirements or profitability.
  • Our products generate large-scale complex data which requires advanced analytics to interpret.
  • We may be unable to consistently manufacture our instruments and consumables to the necessary specifications or in quantities necessary to meet demand at an acceptable cost or at an acceptable performance level.
  • Our instruments, consumables and related components are specialized, complex and difficult to manufacture. We could experience production problems that impact our ability to manufacture and ship our instruments, consumables and related components, which would materially and adversely affect our business, financial condition and results of operations.
  • Undetected errors or defects in our solutions could harm our reputation and decrease market acceptance of our solutions.
  • We are significantly dependent upon revenue generated from the sale of our Chromium solutions, and in particular our Universal Gene Expression and Flex solutions.
  • Doing business internationally creates operational and financial risks for our business.
  • Our business in China subjects us to unique commercial, operational, competitive and regulatory risks.
  • We and our customers are dependent on single source and sole source suppliers for some of the equipment, components and materials used in our products and in conjunction with our products and the loss of any of these suppliers could harm our business.
  • Certain disruptions in supply of, and changes in the competitive environment for, raw materials integral to the manufacturing of our products may adversely affect our profitability.
  • Our limited operating history and fluctuations in revenue make it difficult to evaluate our future prospects and the risks and challenges we may encounter.
  • If we do not sustain or successfully manage our growth and anticipated growth, our business and prospects will be harmed.
  • If our existing and new products or new versions of existing products fail to achieve and sustain sufficient scientific acceptance, we will not generate expected revenue and our prospects may be harmed.
  • Our results of operations could be materially adversely affected by fluctuations in currency exchange rates.
  • We depend on our key personnel and other highly qualified personnel, and if we are unable to recruit, train, retain and ensure the health and safety of our personnel, we may not achieve our goals.
  • If our facilities or our third-party manufacturers’ facilities become unavailable or inoperable, our research and development programs could be adversely impacted and manufacturing of our instruments and consumables could be interrupted.
  • We rely exclusively on commercial carriers to transport our products, including perishable consumables, to our customers in a timely and cost-efficient manner and if delivery of our products is disrupted, our business will be harmed.
  • Costs or other factors related to our facilities and real estate could adversely impact our business.
  • If we fail to offer high-quality customer service, our business and reputation could suffer.
  • Investments and acquisitions could disrupt our business, cause dilution to our stockholders and otherwise harm our business.
  • Seasonality may cause fluctuations in our revenue and results of operations.
  • Our reliance on distributors for sales of our products in certain geographies outside of the United States could limit or prevent us from selling our products and impact our revenue.
  • Uncertain economic or social conditions may adversely impact demand for our products or cause our customers, vendors and suppliers to suffer financial hardship, which could adversely impact our business.
  • Inflationary pressures, and changes in foreign currency exchange rates, interest rates and market value of our investments, including marketable securities, could have a significant effect on results.
  • AI and machine learning technologies may expose us to significant risks, including development and deployment challenges, regulatory uncertainties, competition for investor research and potential hard-to-predict changes to our business, which could adversely affect our business, results of operations and financial condition.
  • If we fail to maintain an effective system of disclosure controls and internal control over financial reporting, our ability to produce timely and accurate financial statements or comply with applicable regulations could be impaired.
  • The illegal distribution and sale by third parties of stolen, counterfeit or unfit versions of our products could have a negative impact on our reputation and business.
  • The investment of marketable securities is subject to risks which may cause losses and affect the liquidity of these investments.
  • Indebtedness may impair our financial and operating flexibility.
  • Risks related to our regulatory environment and taxation
  • Our products could become subject to more onerous regulation by the FDA or other regulatory agencies in the future, which could increase our costs and delay or prevent commercialization of our products, thereby materially and adversely affecting our business, financial condition, results of operations and prospects.
  • Our products, if used for the diagnosis of disease or in other clinical settings, would likely be subject to government regulation, and the regulatory approval and maintenance process for such products may be expensive, time-consuming and uncertain both in timing and in outcome. Since our strategy includes our potential participation in clinical markets, we will be increasingly exposed to these risks.
  • Newly developed Laboratory Development Tests (LDTs) may be subject to new regulatory clearance or approval, and could result in adverse impacts to our business, financial condition, or results of operations.
  • We are subject to risks related to taxation in multiple jurisdictions and changes in tax laws or regulations that are applied adversely to us or our customers may have a material adverse effect on our business, cash flow, financial condition or results of operations.
  • Our ability to use net operating losses to offset future taxable income may be subject to certain limitations.
  • Ethical, legal, privacy and social concerns or governmental restrictions surrounding the use of the genomic and multiomic information and gene editing could reduce demand for our products.
  • Risks related to our intellectual property, information technology and data security
  • Our success will depend on our ability to obtain, maintain and protect our intellectual property rights.
  • If we cannot successfully enforce our intellectual property rights, the commercial value of our products and technologies will be adversely affected and our competitive position may be harmed.
  • We may be subject to claims challenging the inventorship or ownership of our patents and other intellectual property rights.
  • We depend on certain intellectual property rights that are licensed to us. We may be unsuccessful in licensing or acquiring intellectual property rights from third parties that may be necessary to develop, manufacture and/or commercialize our current and/or future products or technologies.
  • If we fail to execute invention assignment agreements with our employees and contractors involved in the development of intellectual property rights or are unable to protect the confidentiality of our trade secrets, the value of our products and technologies and our business and competitive position could be harmed.
  • We may be subject to claims that we or our employees have misappropriated the intellectual property rights of a third party, including trade secrets or know-how, or are in breach of non-competition or non-solicitation agreements with our competitors.
  • Obtaining and maintaining patent protection depends on compliance with various procedural, document submission, fee payment and other requirements imposed by governmental patent agencies, and our patent protection could be reduced or eliminated for non-compliance with these requirements.
  • Changes in patent law or the organizational changes to the USPTO could diminish the value of our patents in general, thereby impairing our ability to protect our current and future products, services or technologies, and could increase the uncertainties and costs surrounding the prosecution of our patent applications and the enforcement or defense of our current or future patents.
  • Intellectual property rights do not necessarily address all potential threats to our competitive advantage.
  • If our trademarks and trade names are not adequately protected, we may not be able to build name recognition in our markets of interest and our competitive position may be harmed.
  • Our solutions contain third-party open source software components and failure to comply with the terms of the underlying open source software licenses could restrict our ability to sell our products.
  • We collect, process, store, share, disclose and use personal information and other data, which subjects us to governmental regulations and other legal obligations related to privacy and security, and our actual or perceived failure to comply with such obligations could harm our business.
  • If we or our critical third-party providers experience a significant disruption in our information technology systems or breaches of data security, our business could be adversely affected.
  • We rely on on-premise, co-located and third-party data centers and platforms to host our website and other online services, as well as for research and development purposes and any interruptions of service or failures may impair and harm our business.
  • We are subject to certain manufacturing restrictions related to licensed intellectual property rights that were developed with the financial assistance of United States government grants.
  • Risks related to litigation and our intellectual property
  • We may become a party to intellectual property litigation or administrative proceedings that could be expensive, time-consuming, unsuccessful, and could interfere with our ability to develop, manufacture and commercialize our products or technologies.
  • We are involved in lawsuits to protect, enforce or defend our patents and other intellectual property rights, which are expensive, time consuming and could ultimately be unsuccessful.
  • Risks related to ownership of our Class A common stock
  • Sales of a substantial number of shares of our Class A common stock by our existing stockholders could cause the price of our Class A common stock to decline.
  • The multi-class structure of our common stock has the effect of concentrating voting control with those stockholders who held our capital stock prior to the completion of our IPO, including our co-founders, and may depress the trading price of our Class A common stock.
  • Delaware law and provisions in our amended and restated certificate of incorporation and amended and restated bylaws might discourage, delay or prevent a change in control of our company or changes in our management and, therefore, depress the trading price of our Class A common stock.
  • Our amended and restated bylaws designate a state or federal court located within the State of Delaware as the exclusive forum for substantially all disputes between us and our stockholders, which could limit our stockholders’ ability to choose the judicial forum for disputes with us or our directors, officers or employees.
  • General risk factors
  • We may fail to meet our publicly announced guidance or other expectations about our business, which could cause our stock price to decline.
  • The market price of our Class A common stock may be volatile, which could result in substantial losses for investors.
  • Securities analysts may not publish favorable research or reports about our business or may publish no information at all, which could cause our stock price or trading volume to decline.
  • We have incurred and will continue to incur increased costs as a result of operating as a public company, and our management will be required to devote substantial time to compliance initiatives and corporate governance practices, including maintaining an effective system of internal controls over financial reporting.

Legal proceedings

See Note 7, Commitments and Contingencies, to the consolidated financial statements included in Item 8 of Part II of this Annual Report on Form 10-K for information regarding certain legal proceedings in which we are involved.

We are regularly subject to lawsuits, claims, arbitration proceedings, administrative actions and other legal and regulatory proceedings involving intellectual property disputes, commercial disputes, competition and other matters, and we may become subject to additional types of lawsuits, claims, arbitration proceedings, administrative actions, government investigations and legal and regulatory proceedings in the future and as our business grows, including proceedings related to product liability or our acquisitions, securities issuances or our business practices, including public disclosures about our business. Our success depends in part on our non-infringement of the patents or proprietary rights of third parties. In the past, third parties have asserted and may in the future assert that we are employing their proprietary technology without authorization. We have been involved in multiple patent litigation matters and other proceedings in the past and we expect that given the litigious history of our industry and the high profile of operating as a public company, third parties may claim that our products infringe their intellectual property rights. We have also initiated litigation to defend our technology including technology developed through our significant investments in research and development. It is our general policy not to out-license our patents but to protect our sole right to own and practice them. There are inherent uncertainties in these legal matters, some of which are beyond management’s control, making the ultimate outcomes difficult to predict.

The opening of Item 3, Legal Proceedings.19

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