ZVRA on Nasdaq

ZEVRA THERAPEUTICS, INC.

American pharmaceutical preparations company based in Celebration.

Price unavailable

Last updated Oct 18, 2026.

Overview

Compare with Zymeworks, Theravance Biopharma, Inc. or ImmunoGen Inc., or pick any stock.

  • TickerZVRA on Nasdaq
  • IndustryPharmaceutical Preparations
  • HeadquartersCelebration, United States
  • Incorporated inDE2
  • Business address101 Federal Street, Boston, Ma 021102
  • Filer categoryNon-accelerated filer, Smaller reporting company2

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-59.1%Operating margin3
78.2%Net margin3
350.9%Revenue growth, 20253
53.8%Return on equity3
0.40×Debt to equity3
-$2.4MFree cash flow3

What sells

Revenue by product, business segment and region, as the company reports it to the SEC.

Products and services

Miplyffa brought in 99% of the revenue ZEVRA THERAPEUTICS, INC. broke down this way in fiscal 2025.

  1. Miplyffa$87.4M399%up 765% from 2024
  2. Olpruva$800.0K31%up 700% from 2024
Products and services by year
Products and services20242025
Miplyffa$10.1M$87.4M
Olpruva$100.0K$800.0K

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Selling, general and admin47¢$77.6M
  • Income tax2¢$3.4M
  • Profit51¢$83.2M

Out of $106.5M in revenue.3

Financial statements

Revenue456783$106.5M in 2025+729% since 2019
0$50.0M$100.0M$150.0M2019: $12.8M$12.8M20192020: $13.3M$13.3M2020+3%2021: $28.6M$28.6M2021+116%2022: $10.2M$10.2M2022−65%2023: $27.5M$27.5M2023+170%2024: $23.6M$23.6M2024−14%2025: $106.5M$106.5M2025+351%
Operating income456783-$62.9M in 2025+209% since 2019
-$100.0M-$75.0M-$50.0M-$25.0M0$25.0M2019: -$20.3M-$20.3M20192020: -$5.6M-$5.6M2020−72%2021: $7.7M$7.7M20212022: -$42.6M-$42.6M20222023: -$49.6M-$49.6M2023+17%2024: -$87.0M-$87.0M2024+75%2025: -$62.9M-$62.9M2025−28%
Net income456783$83.2M in 2025
-$150.0M-$100.0M-$50.0M0$50.0M$100.0M2019: -$24.5M-$24.5M20192020: -$12.8M-$12.8M2020−48%2021: -$8.6M-$8.6M2021−33%2022: -$26.8M-$26.8M2022+213%2023: -$46.0M-$46.0M2023+72%2024: -$105.5M-$105.5M2024+129%2025: $83.2M$83.2M2025

Every line of the income statement as filed: the last 2 fiscal years, latest first.3

Period ending2025-12-312024-12-31
Revenue, net$106.5M$23.6M
Cost of product revenue (excluding $X and $X in intangible asset amortization for the years ended XXX XX, 20XX, and 20XX, respectively, shown separately below)$16.5M$7.4M
Impairment of intangible assets$58.7M$0
Research and development$12.7M$42.1M
Selling, general and administrative$77.6M$54.9M
Total operating expenses$90.4M$97.0M
Loss from operations-$62.9M-$87.0M
Gain on sale of PRV$148.3M$0
Interest expense-$8.0M-$7.4M
Fair value adjustment related to warrant and CVR liability$2.2M$2.1M
Fair value adjustment related to investments$149.0K-$18.0K
Interest and other income, net$6.9M$2.2M
Total other income (expense)$149.6M-$3.1M
Income (loss) before income taxes$86.7M-$90.1M
Income tax expense-$3.4M-$15.4M
Net income (loss)$83.2M-$105.5M
Basic (in dollars per share)$1.40-$2.28
Diluted (in dollars per share)$1.35-$2.28
Basic (in shares)55.3M shares46.3M shares
Diluted (in shares)57.3M shares46.3M shares
Intangible asset amortization$3.9M$6.2M

Compare ZEVRA THERAPEUTICS, INC. with another company

Leadership

Who has led ZEVRA THERAPEUTICS, INC., and when. Pick a name to see everywhere that person has worked.

Board members and other officers (25)

Former names

  • KEMPHARM, INCMay 30, 2013 to Feb 24, 20232
  • KEMPHARM INCMay 6, 2008 to Jun 30, 20112

Timeline

  1. Oct 10, 2023New chief executive Neil F. McFarlane becomes CEO12
  2. Jan 11, 2023New chief executive Richard W. Pascoe becomes CEO11
  3. Apr 15, 2015New chief executive Travis C. Mickle becomes CEO13
  4. May 28, 2014Founded ZEVRA THERAPEUTICS, INC. is founded41

Filings

363 filings to the SEC since October 2021: 5 annual reports, 15 quarterly reports, 75 major events, 140 insider forms, 21 large holders, 107 other. The latest 20:

  1. Oct 13, 2026144 EDGAR
  2. Oct 13, 20264 EDGAR
  3. Aug 17, 20264 EDGAR
  4. Aug 14, 2026144 EDGAR
  5. Aug 14, 2026SCHEDULE 13G/A EDGAR
  6. Aug 12, 20264 EDGAR
  7. Aug 6, 2026SCHEDULE 13G/A EDGAR
  8. Aug 5, 202610-Q EDGAR
  9. Aug 5, 20268-K EDGAR
  10. Jul 31, 2026SCHEDULE 13G EDGAR
  11. Jul 8, 2026144 EDGAR
  12. Jun 23, 20264 EDGAR
  13. Jun 18, 20264 EDGAR
  14. Jun 18, 20264 EDGAR
  15. Jun 18, 20264 EDGAR
  16. Jun 18, 20264 EDGAR
  17. Jun 18, 20264 EDGAR
  18. Jun 18, 20264 EDGAR
  19. Jun 5, 20268-K EDGAR
  20. May 29, 20264 EDGAR

The 363 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last three years, summarized. The full record is on SEC EDGAR.

Insider trades and holders

Large holders

Investors who own more than 5% must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively. 21 such filings since October 2021, the latest 10:

  1. Aug 14, 2026SCHEDULE 13G/A
  2. Aug 6, 2026SCHEDULE 13G/A
  3. Jul 31, 2026SCHEDULE 13G
  4. May 6, 2026SCHEDULE 13G
  5. Mar 27, 2026SCHEDULE 13G/A
  6. Nov 14, 2025SCHEDULE 13G/A
  7. Nov 13, 2025SCHEDULE 13G/A
  8. Feb 14, 2025SCHEDULE 13G/A
  9. Feb 12, 2025SCHEDULE 13G
  10. Feb 5, 2025SCHEDULE 13G/A

From Forms 4 and Schedules 13D and 13G filed with the SEC.

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
BlackRock, Inc.5,108,871$73.3M0.0%+652,395
Fmr LLC4,915,717$70.5M0.0%+1,703,840
Woodline Partners LP4,785,771$68.6M0.2%+1,334,828
Nantahala Capital Management, LLC3,594,952$51.6M1.6%+1,073,016
Vanguard Capital Management LLC2,638,910$37.8M0.0%+169,582
State Street Corp1,681,999$24.1M0.0%+120,430
Geode Capital Management, LLC1,540,936$22.1M0.0%+169,079
D. E. Shaw & Co., Inc.1,306,949$18.7M0.0%+460,492
Qube Research & Technologies Ltd1,241,343$17.8M0.0%+399,024
Morgan Stanley1,203,875$17.3M0.0%+11,613
Legal & General Group Plc1,201,668$17.2M0.0%+38,578
Dimensional Fund Advisors LP958,836$13.7M0.0%+404,034
Royce & Associates LP882,658$12.7M0.1%−106,016
683 Capital Management, LLC855,000$12.3M1.2%−120,000
Kingdon Capital Management, L.l.c.775,000$11.1M1.5%No change
Retirement Planning Co of New England, Inc.634,410$9.1M3.3%−16,738
Jupiter Topco LLC613,403$8.8M0.0%New
Arrowstreet Capital, Limited Partnership597,162$8.6M0.0%New
Goldman Sachs Group Inc545,551$7.8M0.0%−197,573
Vanguard Portfolio Management LLC541,109$7.8M0.0%+74,806
Northern Trust Corp486,498$7.0M0.0%+49,548
Swedbank AB439,410$6.3M0.0%New
Schroder Investment Management Group439,328$6.2M0.0%−66,705
Tudor Investment Corp Et Al415,058$6.0M0.0%−28,051
Stratos Wealth Partners, LTD.408,000$5.9M0.1%No change

13F reports cover disclosed long positions in U.S. stocks only.

Sources

The numbers on this page point here. Each one links to the record it came from.

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