ZYME on Nasdaq

Zymeworks

Logo: Unknown author Unknown author, CC BY-SA 4.0, via Wikimedia Commons4

Canadian biotechnology company

Zymeworks Inc. is a publicly held biotechnology company based in Vancouver, British Columbia, that develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases.3 From Wikipedia, CC BY-SA 4.0

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Last updated Oct 18, 2026.

Overview

2003Founded1

Compare with ZEVRA THERAPEUTICS, INC., Theravance Biopharma, Inc. or ImmunoGen Inc., or pick any stock.

  • TickerZYME on Nasdaq1
  • Industrypharmaceutical industry1
  • HeadquartersVancouver1
  • Websitewww.zymeworks.com
  • Legal formDelaware corporation1

Zymeworks Inc. is a publicly held biotechnology company based in Vancouver,3

Financials

From the company’s reports to the SEC. Every number links to the filing it came from.

Key numbers, fiscal 2025

-87.3%Operating margin5
-76.6%Net margin5
38.9%Revenue growth, 20255
-30.2%Return on equity5
-$34.5MFree cash flow5

Where the money goes

Where each dollar of revenue went, fiscal 2025

  • Other costs99¢$104.6M
  • Income tax1¢$1.4M

Out of $106.0M in revenue.5 The company lost money this year.

Financial statements

Revenue67895$106.0M in 2025+259% since 2019
0$200.0M$400.0M$600.0M2019: $29.5M$29.5M20192020: $39.0M$39.0M2020+32%2021: $26.7M$26.7M2021−32%2022: $412.5M$412.5M2022+1446%2023: $76.0M$76.0M2023−82%2024: $76.3M$76.3M2024+0%2025: $106.0M$106.0M2025+39%
Operating income67895-$92.5M in 2025−39% since 2019
-$300.0M-$200.0M-$100.0M0$100.0M$200.0M2019: -$151.3M-$151.3M20192020: -$187.5M-$187.5M2020+24%2021: -$215.6M-$215.6M2021+15%2022: $130.5M$130.5M20222023: -$138.1M-$138.1M20232024: -$137.1M-$137.1M2024−1%2025: -$92.5M-$92.5M2025−33%
Net income67895-$81.1M in 2025−44% since 2019
-$300.0M-$200.0M-$100.0M0$100.0M$200.0M2019: -$145.4M-$145.4M20192020: -$180.6M-$180.6M2020+24%2021: -$211.8M-$211.8M2021+17%2022: $124.3M$124.3M20222023: -$118.7M-$118.7M20232024: -$122.7M-$122.7M2024+3%2025: -$81.1M-$81.1M2025−34%

Every line of the income statement as filed: the last 3 fiscal years, latest first.5

Period ending2025-12-312024-12-312023-12-31
Research and development collaborations (note 11)$106.0M$76.3M$76.0M
Research and development$137.0M$134.6M$143.6M
General and administrative$61.5M$61.5M$70.4M
Impairment on IPR&D (note 6)$0$17.3M$0
Total operating expenses$198.5M$213.4M$214.1M
Loss from operations-$92.5M-$137.1M-$138.1M
Interest income$13.4M$19.9M$19.7M
Other (expense) income, net (note 12)-$559.0K$558.0K-$894.0K
Total other income, net$12.8M$20.5M$18.8M
Loss before income taxes-$79.8M-$116.6M-$119.2M
Income tax (expense) recovery (note 13)-$1.4M-$6.1M$568.0K
Net loss-$81.1M-$122.7M-$118.7M
Unrealized income (loss) on available for sale securities, net of tax of nil (note 5)$873.0K-$349.0K$56.0K
Total other comprehensive income (loss)$873.0K-$349.0K$56.0K
Comprehensive loss-$80.3M-$123.0M-$118.6M
Basic (in dollars per share)-$1.08-$1.62-$1.72
Diluted (in dollars per share)-$1.08-$1.62-$1.72
Basic (in shares)75.4M shares75.8M shares68.9M shares
Diluted (in shares)75.4M shares75.9M shares68.9M shares
Unrealized loss on available for sale securities, tax$0$0$0

Compare Zymeworks with another company

Leadership

Who has led Zymeworks, and when. Pick a name to see everywhere that person has worked.

Board members and other officers (41)

Products and brands

  • medication

Listed on Wikidata.1

Timeline

  1. Jan 18, 2022New chief executive Kenneth Galbraith becomes CEO13
  2. Jan 2, 2019New chief executive Ali Tehrani becomes CEO15
  3. 2003Founded Founded1

Filings

450 filings to the SEC since October 2021: 7 annual reports, 15 quarterly reports, 138 major events, 135 insider forms, 55 large holders, 1 private raises, 99 other. The latest 20:

  1. Oct 9, 20264 EDGAR
  2. Oct 9, 2026144 EDGAR
  3. Sep 23, 20268-K EDGAR
  4. Aug 25, 20268-K EDGAR
  5. Aug 6, 202610-Q EDGAR
  6. Aug 6, 20268-K EDGAR
  7. Jul 6, 20264 EDGAR
  8. Jun 29, 20268-K EDGAR
  9. May 15, 20264 EDGAR
  10. May 15, 20263 EDGAR
  11. May 15, 2026SCHEDULE 13G/A EDGAR
  12. May 14, 20268-K EDGAR
  13. May 7, 202610-Q EDGAR
  14. May 7, 20268-K EDGAR
  15. Apr 15, 2026SCHEDULE 13G EDGAR
  16. Apr 10, 20264 EDGAR
  17. Apr 10, 20264 EDGAR
  18. Apr 10, 20263 EDGAR
  19. Apr 10, 20263 EDGAR
  20. Apr 7, 20264 EDGAR

The 450 filings since October 2021 can be filtered by form type and year here when JavaScript is on.

Every filing from the last three years, summarized. The full record is on SEC EDGAR.

Insider trades and holders

Large holders

Investors who own more than 5% must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively. 55 such filings since October 2021, the latest 10:

  1. May 15, 2026SCHEDULE 13G/A
  2. Apr 15, 2026SCHEDULE 13G
  3. Feb 13, 2026SCHEDULE 13G/A
  4. Feb 12, 2026SCHEDULE 13G/A
  5. Nov 19, 2025SCHEDULE 13D/A
  6. Nov 14, 2025SCHEDULE 13G/A
  7. Nov 14, 2025SCHEDULE 13G/A
  8. Aug 14, 2025SCHEDULE 13G/A
  9. Jun 27, 2025SCHEDULE 13D
  10. May 7, 2025SCHEDULE 13G/A

From Forms 4 and Schedules 13D and 13G filed with the SEC.

Money raised

Private offerings the company reported to the SEC on Form D.

  1. Dec 28, 2023Raised $50 million in a private offering of equity Form D: $50 million offered in all Form D

Held by these funds

The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.

FundSharesValueShare of the fundChange
EcoR1 Capital, LLC22,970,388$600.4M29.8%No change
Rubric Capital Management LP7,000,000$183.0M1.7%No change
BlackRock, Inc.4,251,030$111.1M0.0%−302,858
Perceptive Advisors LLC4,182,953$109.3M1.7%+672,875
Bvf Inc/il3,649,142$95.4M2.4%−85,000
Assenagon Asset Management S.A.2,504,054$65.5M0.0%+1,776,068
Morgan Stanley2,231,260$58.3M0.0%−249,308
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,781,116$46.6M0.0%−126,923
Vanguard Capital Management LLC1,558,998$40.8M0.0%−146,582
Nextech Invest Ltd.1,113,946$29.1M1.4%No change
State Street Corp1,088,216$28.4M0.0%+76,439
Dimensional Fund Advisors LP994,955$26.0M0.0%−144,180
Citadel Advisors LLC914,136$23.9M0.0%−235,882
Nomura Asset Management International Inc.889,802$23.3M0.0%New
Fmr LLC702,568$18.4M0.0%+35,415
Geode Capital Management, LLC692,410$18.1M0.0%+32,470
Prosight Management, LP674,434$17.6M3.0%+135,385
Qube Research & Technologies Ltd593,590$15.5M0.0%+81,653
Vanguard Portfolio Management LLC510,032$13.3M0.0%+10,157
Redmile Group, LLC491,654$12.9M0.9%No change
Capricorn Fund Managers Ltd486,529$12.7M1.0%−520,681
Goldman Sachs Group Inc470,822$12.3M0.0%−128,664
Arrowstreet Capital, Limited Partnership418,497$10.9M0.0%−325,401
Deutsche Bank Ag\397,190$10.4M0.0%−524,060
Hillsdale Investment Management Inc.382,922$10.0M0.2%+37,300

13F reports cover disclosed long positions in U.S. stocks only.

Sources

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