1y return−48.0%S&P 500 +20.9%
These returns are for its stock picks as disclosed on Form 13F: last quarter's holdings, valued at this quarter's prices. They miss trades within each quarter, short positions, options, bonds, cash and fees, so they aren't the returns its clients got.
$100 invested in its stock picks
Since December 31, 2024: $39 against $127 in the S&P 500.2
BIOS Capital Management, LPS&P 500 (SPY)
Top holdings
At the end of June 30, 2026. Change is in shares since the quarter before.2
| Stock | Value | Share of portfolio | Change |
|---|---|---|---|
| ACTUActuate Therapeutics Inc | $15.4M | 36.9% | |
| IRDOpus Genetics Inc | $15.1M | 36.3% | |
| CGTXCognition Therapeutics Inc | $6.9M | 16.6% | |
| RNTXRein Therapeutics Inc | $3.1M | 7.4% | +50.4% |
| LTRNLantern Pharma Inc | $1.0M | 2.5% | −71.1% |
| INABIn8bio Inc | $114K | 0.3% | −51.8% |
Best picks still held
How each current holding has done since the quarter it first appeared in its filings (up to six years back).
| Stock | Held since | Return since | Now worth |
|---|---|---|---|
| IRDOpus Genetics Inc | December 31, 2024 | +245.4% | $15.1M |
| INABIn8bio Inc | December 31, 2025 | −39.7% | $114K |
| RNTXRein Therapeutics Inc | December 31, 2024 | −54.8% | $3.1M |
| ACTUActuate Therapeutics Inc | December 31, 2024 | −80.8% | $15.4M |
Quarter by quarter
| Quarter | Its picks | S&P 500 |
|---|---|---|
| June 30, 2026 | −23.2% | +14.8% |
| March 31, 2026 | −36.1% | −4.6% |
| December 31, 2025 | −6.5% | +2.4% |
| September 30, 2025 | +13.2% | +7.8% |
| June 30, 2025 | −10.7% | +10.5% |
| March 31, 2025 | −15.9% | −4.6% |
Sources
Every number on this page points here. Each one links to the public record.
- 1SEC EDGAR: BIOS Capital Management, LP Form 13F filingshttps://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=1813845&type=13F-HR&dateb=&owner=include&count=40CIK 1813845
- 2SEC: 13F for the quarter ended June 30, 2026https://www.sec.gov/Archives/edgar/data/1813845/000181384526000004/Filed August 14, 2026 · accession 0001813845-26-000004