1y return+76.9%S&P 500 +20.9%
3y return+97.0%S&P 500 +68.5%
5y return+27.2%S&P 500 +74.5%
These returns are for its stock picks as disclosed on Form 13F: last quarter's holdings, valued at this quarter's prices. They miss trades within each quarter, short positions, options, bonds, cash and fees, so they aren't the returns its clients got.
$100 invested in its stock picks
Since March 31, 2018: $348 against $284 in the S&P 500.2
Crestline Management, L.P.S&P 500 (SPY)
Top holdings
At the end of June 30, 2026. Change is in shares since the quarter before.2
| Stock | Value | Share of portfolio | Change |
|---|---|---|---|
| DNLIDenali Therapeutics Inc | $49.1M | 91.9% | −13.6% |
| SANASana Biotechnology Inc | $2.6M | 4.9% | |
| EGHT8x8 Inc New | $1.7M | 3.2% |
Best picks still held
How each current holding has done since the quarter it first appeared in its filings (up to six years back).
| Stock | Held since | Return since | Now worth |
|---|---|---|---|
| DNLIDenali Therapeutics Inc | June 30, 2020 | +6.4% | $49.1M |
| EGHT8x8 Inc New | December 31, 2022 | −60.4% | $1.7M |
| SANASana Biotechnology Inc | June 30, 2021 | −82.2% | $2.6M |
Quarter by quarter
| Quarter | Its picks | S&P 500 |
|---|---|---|
| June 30, 2026 | +32.3% | +14.8% |
| March 31, 2026 | +10.9% | −4.6% |
| December 31, 2025 | +13.1% | +2.4% |
| September 30, 2025 | +6.7% | +7.8% |
| June 30, 2025 | +7.2% | +10.5% |
| March 31, 2025 | −6.6% | −4.6% |
| December 31, 2024 | −1.6% | +2.1% |
| September 30, 2024 | +6.2% | +5.4% |
| June 30, 2024 | +0.5% | +4.0% |
| March 31, 2024 | +6.5% | +10.0% |
| December 31, 2023 | +9.9% | +11.2% |
| September 30, 2023 | −9.5% | −3.6% |
| June 30, 2023 | +10.2% | +8.3% |
| March 31, 2023 | −0.8% | +7.0% |
| December 31, 2022 | +1.3% | +7.1% |
| September 30, 2022 | −0.6% | −5.3% |
| June 30, 2022 | −14.3% | −16.5% |
| March 31, 2022 | −11.5% | −4.9% |
| December 31, 2021 | −3.1% | +10.7% |
| September 30, 2021 | −20.3% | +0.3% |
Sources
Every number on this page points here. Each one links to the public record.
- 1SEC EDGAR: Crestline Management, L.P. Form 13F filingshttps://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=1536054&type=13F-HR&dateb=&owner=include&count=40CIK 1536054
- 2SEC: 13F for the quarter ended June 30, 2026https://www.sec.gov/Archives/edgar/data/1536054/000131586326000592/Filed August 14, 2026 · accession 0001315863-26-000592