Funds · 13F filer · New York, NY

Affinity Asset Advisors, LLC

$2.0B in 101 U.S. stocks and ETFs at the end of June 30, 2026, as reported to the SEC.1

1y return+112.5%S&P 500 +20.9%
3y return+148.3%S&P 500 +68.5%
5y return+60.8%S&P 500 +74.5%

These returns are for its stock picks as disclosed on Form 13F: last quarter's holdings, valued at this quarter's prices. They miss trades within each quarter, short positions, options, bonds, cash and fees, so they aren't the returns its clients got.

$100 invested in its stock picks

Since March 31, 2021: $150 against $188 in the S&P 500.2

Affinity Asset Advisors, LLCS&P 500 (SPY)
$48$100$18820212026

Top holdings

At the end of June 30, 2026. Change is in shares since the quarter before.2

StockValueShare of portfolioChange
Roivant Sciences LtdCUSIP G76279101$132.7M6.6%+33.9%
Apogee Therapeutics IncCUSIP 03770N101$131.0M6.5%−23.2%
SYRESpyre Therapeutics Inc$113.6M5.6%
XENEXenon Pharmaceuticals Inc$96.3M4.8%−4.8%
ERASErasca Inc$96.2M4.8%−1.9%
INSMInsmed Inc$69.3M3.4%+35.4%
PRAXPraxis Precision Medicines I$61.9M3.1%+8.8%
Alkermes PLCCUSIP G01767105$58.9M2.9%−16.7%
ORKAOruka Therapeutics Inc$56.2M2.8%+18.1%
ANABAnaptysbio Inc$55.8M2.8%−12.1%
AVTXAvalo Therapeutics Inc$53.6M2.7%+116.3%
CYTKCytokinetics Inc$46.9M2.3%−21.5%
RVMDRevolution Medicines Inc$46.8M2.3%+150.0%
ABVXAbivax Sa$44.0M2.2%−18.5%
TRAXFirst Tracks Biotherapeutics$40.9M2.0%New
DNTHDianthus Therapeutics Inc$39.0M1.9%+14.3%
STROSutro Biopharma Inc$38.9M1.9%+9.6%
Nuvalent IncCUSIP 670703107$34.0M1.7%−8.3%
TRVITrevi Therapeutics Inc$33.6M1.7%−10.0%
OVIDOvid Therapeutics Inc$27.3M1.4%−4.6%
LXEOLexeo Therapeutics Inc$27.0M1.3%+15.0%
CLDXCelldex Therapeutics Inc New$26.0M1.3%+40.0%
BLTEBelite Bio Inc$25.4M1.3%+153.8%
ELVNEnliven Therapeutics Inc$25.4M1.3%−14.8%
Forte Biosciences IncCUSIP 34962G208$24.3M1.2%+13.2%

Best picks still held

How each current holding has done since the quarter it first appeared in its filings (up to six years back).

StockHeld sinceReturn sinceNow worth
SYRESpyre Therapeutics IncSeptember 30, 2023+624.7%$113.6M
Apogee Therapeutics IncCUSIP 03770N101September 30, 2023+523.1%$131.0M
RVMDRevolution Medicines IncSeptember 30, 2025+301.0%$46.8M
ORKAOruka Therapeutics IncSeptember 30, 2024+288.3%$56.2M
Roivant Sciences LtdCUSIP G76279101March 31, 2025+250.7%$132.7M
TVTXTravere Therapeutics IncDecember 31, 2024+226.1%$17.0M
PTGXProtagonist Therapeutics IncDecember 31, 2024+217.6%$21.1M
TRVITrevi Therapeutics IncMarch 31, 2025+196.5%$33.6M
STROSutro Biopharma IncDecember 31, 2025+186.9%$38.9M
SVRASavara IncJune 30, 2025+170.2%$15.5M

Sold off last quarter

  • Centessa Pharmaceuticals PLCCUSIP 152309100 was $55.6M
  • Arcellx IncCUSIP 03940C100 was $41.7M
  • Terns Pharmaceuticals IncCUSIP 880881107 was $29.7M
  • Ascendis Pharma A/sCUSIP 04351P101 was $21.7M
  • BBIOBridgebio Pharma Inc was $11.1M
  • Wave Life Sciences LtdCUSIP Y95308105 was $10.2M
  • Engene Holdings IncCUSIP 29286M105 was $4.2M
  • CORTCorcept Therapeutics Inc was $2.0M
  • Kezar Life Sciences IncCUSIP 49372L209 was $1.7M

Quarter by quarter

QuarterIts picksS&P 500
June 30, 2026+20.4%+14.8%
March 31, 2026+6.8%−4.6%
December 31, 2025+30.3%+2.4%
September 30, 2025+26.8%+7.8%
June 30, 2025+6.3%+10.5%
March 31, 2025−15.1%−4.6%
December 31, 2024−5.6%+2.1%
September 30, 2024+13.4%+5.4%
June 30, 2024−13.3%+4.0%
March 31, 2024+18.5%+10.0%
December 31, 2023+33.5%+11.2%
September 30, 2023−11.8%−3.6%
June 30, 2023+13.1%+8.3%
March 31, 2023−2.3%+7.0%
December 31, 2022+9.9%+7.1%
September 30, 2022+4.1%−5.3%
June 30, 2022−20.1%−16.5%
March 31, 2022−14.4%−4.9%
December 31, 2021−17.8%+10.7%
September 30, 2021−8.9%+0.3%

Sources

Every number on this page points here. Each one links to the public record.

  1. 1
    CIK 1773195
  2. 2
    Filed August 13, 2026 · accession 0001011438-26-000516