TRVI on Nasdaq
Trevi Therapeutics, Inc.
American pharmaceutical preparations company based in New Haven. Summary from the record
Price unavailable
Last updated Oct 19, 2026.
Overview
- TickerTRVI on Nasdaq1
- IndustryPharmaceutical Preparations1
- HeadquartersNew Haven, Connecticut1
- Incorporated inDE2
- Business address195 Church Street, 16Th Floor, New Haven, Ct 065102
- Filer categoryNon-accelerated filer, Smaller reporting company2
- Legal formCorporation
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We are a clinical-stage biopharmaceutical company focused on the development and commercialization of the investigational therapy Haduvio (oral nalbuphine ER) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis, or IPF, non-IPF interstitial lung disease, or non-IPF ILD, and refractory chronic cough, or RCC.3 From its latest annual report
Financials
From the company’s reports to the SEC. Every number links to the filing it came from.
Financial statements
Every line of the income statement as filed: the last 2 fiscal years, latest first.9
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Research and development | $33.5M | $39.4M |
| General and administrative | $15.8M | $12.1M |
| Total operating expenses | $49.3M | $51.5M |
| Loss from operations | -$49.3M | -$51.5M |
| Interest income, net | $6.5M | $3.6M |
| Other expense, net | -$31.0K | -$15.0K |
| Interest expense | $0 | -$4.0K |
| Total other income, net | $6.5M | $3.6M |
| Loss before income taxes | -$42.8M | -$47.9M |
| Income tax benefit | -$64.0K | -$30.0K |
| Net loss | -$42.8M | -$47.9M |
| Basic net loss per common share outstanding | -$0.32 | -$0.47 |
| Diluted net loss per common share outstanding | -$0.32 | -$0.47 |
| Weighted average common shares used in net loss per share attributable to common stockholders, basic | 134.7M shares | 102.0M shares |
| Weighted average common shares used in net loss per share attributable to common stockholders, diluted | 134.7M shares | 102.0M shares |
| Net unrealized gains on available-for-sale marketable securities | $87.0K | $90.0K |
| Comprehensive loss | -$42.7M | -$47.8M |
No quarter-by-quarter statement was filed.
Every line of the balance sheet as filed: the last 3 fiscal years (annual) or 3 quarters (quarterly), latest first.9
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Cash and cash equivalents | $18.9M | $34.1M | |
| Marketable securities | $169.3M | $73.5M | |
| Prepaid expenses | $1.3M | $939.0K | |
| Other current assets | $2.1M | $867.0K | |
| Total current assets | $191.7M | $109.4M | |
| Operating lease right-of-use assets | $677.0K | $915.0K | |
| Property, equipment and leasehold improvements, net | $178.0K | $157.0K | |
| Other non-current assets | $928.0K | $243.0K | |
| Finance lease right-of-use assets | $0 | $157.0K | |
| Total assets | $193.4M | $110.9M | |
| Accounts payable | $3.9M | $3.4M | |
| Accrued expenses | $5.5M | $6.8M | |
| Operating lease liabilities | $307.0K | $254.0K | |
| Finance lease liabilities | $0 | $31.0K | |
| Total current liabilities | $9.7M | $10.5M | |
| Operating lease liabilities | $446.0K | $747.0K | |
| Total liabilities | $10.2M | $11.3M | |
| Common stock: $0.001 par value; 200,000,000 shares authorized at December 31, 2025 and December 31, 2024; and 128,306,056 and 93,602,631 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively. | $128.0K | $94.0K | |
| Additional paid-in capital | $512.8M | $386.5M | |
| Accumulated other comprehensive income | $148.0K | $61.0K | |
| Accumulated deficit | -$329.8M | -$287.0M | |
| Total stockholders equity | $183.2M | $99.6M | $82.5M |
| Total liabilities and stockholders equity | $193.4M | $110.9M | |
| Preferred Stock, Par or Stated Value Per Share | $0.00 | $0.00 | |
| Preferred Stock, Shares Authorized | 5.0M shares | 5.0M shares | |
| Preferred Stock, Shares Issued | 0 shares | 0 shares | |
| Preferred Stock, Shares Outstanding | 0 shares | 0 shares | |
| Common Stock, Par or Stated Value Per Share | $0.00 | $0.00 | |
| Common Stock, Shares Authorized | 200.0M shares | 200.0M shares | |
| Common Stock, Shares, Issued | 128.3M shares | 93.6M shares | |
| Common Stock, Shares, Outstanding | 128.3M shares | 93.6M shares |
| Period ending | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Cash and cash equivalents | $18.9M | $34.1M | |
| Marketable securities | $169.3M | $73.5M | |
| Prepaid expenses | $1.3M | $939.0K | |
| Other current assets | $2.1M | $867.0K | |
| Total current assets | $191.7M | $109.4M | |
| Operating lease right-of-use assets | $677.0K | $915.0K | |
| Property, equipment and leasehold improvements, net | $178.0K | $157.0K | |
| Other non-current assets | $928.0K | $243.0K | |
| Finance lease right-of-use assets | $0 | $157.0K | |
| Total assets | $193.4M | $110.9M | |
| Accounts payable | $3.9M | $3.4M | |
| Accrued expenses | $5.5M | $6.8M | |
| Operating lease liabilities | $307.0K | $254.0K | |
| Finance lease liabilities | $0 | $31.0K | |
| Total current liabilities | $9.7M | $10.5M | |
| Operating lease liabilities | $446.0K | $747.0K | |
| Total liabilities | $10.2M | $11.3M | |
| Common stock: $0.001 par value; 200,000,000 shares authorized at December 31, 2025 and December 31, 2024; and 128,306,056 and 93,602,631 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively. | $128.0K | $94.0K | |
| Additional paid-in capital | $512.8M | $386.5M | |
| Accumulated other comprehensive income | $148.0K | $61.0K | |
| Accumulated deficit | -$329.8M | -$287.0M | |
| Total stockholders equity | $183.2M | $99.6M | $82.5M |
| Total liabilities and stockholders equity | $193.4M | $110.9M | |
| Preferred Stock, Par or Stated Value Per Share | $0.00 | $0.00 | |
| Preferred Stock, Shares Authorized | 5.0M shares | 5.0M shares | |
| Preferred Stock, Shares Issued | 0 shares | 0 shares | |
| Preferred Stock, Shares Outstanding | 0 shares | 0 shares | |
| Common Stock, Par or Stated Value Per Share | $0.00 | $0.00 | |
| Common Stock, Shares Authorized | 200.0M shares | 200.0M shares | |
| Common Stock, Shares, Issued | 128.3M shares | 93.6M shares | |
| Common Stock, Shares, Outstanding | 128.3M shares | 93.6M shares |
Cash flow is reported year to date, not quarter by quarter, so there are no separate quarterly figures.
Every line of the cash flow as filed: the last 2 fiscal years, latest first.9
| Period ending | 2025-12-31 | 2024-12-31 |
|---|---|---|
| Net loss | -$42.8M | -$47.9M |
| Stock-based compensation | $5.2M | $3.6M |
| Operating lease right-of-use assets | $437.0K | $460.0K |
| Depreciation and amortization | $144.0K | $147.0K |
| Accretion of available-for-sale marketable securities, net | -$1.6M | -$1.4M |
| Write off of deferred offering costs | $26.0K | |
| Loss on disposal of property, equipment and leasehold improvements | $7.0K | |
| Prepaid expenses and other current assets | -$1.5M | $2.7M |
| Accrued expenses and other liabilities | -$1.4M | $2.6M |
| Accounts payable | -$598.0K | $1.6M |
| Net cash used in operating activities | -$42.1M | -$38.3M |
| Proceeds from maturities of available-for-sale marketable securities | $76.6M | $77.0M |
| Purchases of available-for-sale marketable securities | -$170.7M | -$98.5M |
| Purchases of property, equipment and leasehold improvements | -$12.0K | -$35.0K |
| Net cash used in investing activities | -$94.1M | -$21.5M |
| Proceeds from offering, net of commissions | $108.2M | $47.0M |
| Proceeds from exercises of warrants | $10.8M | |
| Proceeds from exercises of stock options | $2.1M | $394.0K |
| Proceeds from disgorgement of beneficial owner's short-swing profits | $725.0K | |
| Proceeds from employee stock purchase plan | $118.0K | $70.0K |
| Payments of offering costs | -$809.0K | |
| Payments of finance lease | -$11.0K | -$126.0K |
| Proceeds from at-the-market sales, net of commissions | $14.1M | |
| Net cash provided by financing activities | $121.0M | $61.5M |
| Net (decrease) increase in cash and cash equivalents | -$15.2M | $1.7M |
| Interest paid | -$4.0K | |
| State research tax credits exchanged for cash | $33.0K | $32.0K |
| Offering costs included in accrued expenses | $233.0K |
No quarter-by-quarter statement was filed.
Leadership
Who has led Trevi Therapeutics, Inc., and when. Pick a name to see everywhere that person has worked.
Chief executive
President
Chief financial officer
- Chief executive officerJennifer L. Good Jun 5, 2019 to now12
- PresidentJennifer L. Good Jun 5, 2019 to now12
- Chief financial officerDavid C. Hastings Jan 12, 2026 to now13
- Chief financial officerLisa Delfini Aug 9, 2021 to Jan 12, 202614
- Chief financial officerChristopher Seiter May 7, 2019 to Feb 19, 202115
Board members and other officers (20)
- Chief Development OfficerJames Cassella V. Oct 1, 2024 to now16
- Chief Commercial OfficerFarrell Simon Feb 16, 2023 to now17
- Chief Medical OfficerDavid J. Clark Nov 14, 2022 to Feb 16, 202418
- Chief Development OfficerWilliam P. Forbes Feb 3, 2021 to Jul 1, 202219
- OfficerChristopher Galletta Apr 15, 2021 to now20
- ControllerFrank P. Muscolo May 7, 2019 to Feb 19, 202121
- Chief Development OfficerHelena Brett-Smith May 7, 2019 to Feb 18, 202022
- OfficerJennifer L. Good May 7, 2019 to Feb 18, 202023
- Chief Medical OfficerThomas Sciascia May 7, 2019 to now24
- OfficerYann Mazabraud May 7, 2019 to Feb 18, 202025
- Board memberJames Cassella V. Feb 18, 2020 to Jun 14, 202426
- Board memberDominick Colangelo Jul 1, 2020 to now27
- Board memberAnna Guyer Mitsak May 7, 2019 to May 13, 201928
- Board memberAnne Vanlent May 7, 2019 to now29
- Board memberDavid P. Meeker May 7, 2019 to now30
- Board memberEdward T. Mathers May 7, 2019 to now31
- Board memberEran Nadav May 7, 2019 to May 8, 201932
- Board memberJennifer L. Good May 7, 2019 to now23
- Board memberMette Kirstine Agger May 7, 2019 to May 13, 201933
- Board memberMichael Thomas Heffernan May 7, 2019 to now34
Timeline
- Jun 5, 2019New chief executive Jennifer L. Good becomes CEO12
Filings
335 filings to the SEC since October 2021: 5 annual reports, 15 quarterly reports, 53 major events, 142 insider forms, 54 large holders, 3 private raises, 63 other. The latest 20:
- Sep 17, 20264 EDGAR
- Sep 15, 2026144 EDGAR
- Aug 6, 2026S-8 EDGAR
- Aug 6, 202610-Q EDGAR
- Aug 6, 20268-K EDGAR
- Aug 6, 2026SCHEDULE 13G/A EDGAR
- Jun 4, 20264 EDGAR
- Jun 4, 20264 EDGAR
- Jun 4, 20264 EDGAR
- Jun 4, 20264 EDGAR
- Jun 4, 20264 EDGAR
- Jun 4, 20268-K EDGAR
- May 7, 2026SCHEDULE 13D/A EDGAR
- May 6, 2026SCHEDULE 13G/A EDGAR
- May 5, 202610-Q EDGAR
- May 5, 20268-K EDGAR
- Apr 21, 2026DEF 14A EDGAR
- Apr 21, 2026ARS EDGAR
- Apr 21, 2026DEFA14A EDGAR
- Apr 17, 2026424B5 EDGAR
The 335 filings since October 2021 can be filtered by form type and year here when JavaScript is on.
Every filing from the last five years, summarized. The full record is on SEC EDGAR.
Insider trades
52 open-market trades by officers, directors and large owners since October 2021: 18 buys and 34 sales. Grants, option exercises and gifts are left out.
| Date | Who | Trade | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| Sep 15, 2026 | Heffernan Michael ThomasDirector | Sale | 39,473 | $15.09 | $595.8K | Form 4 |
| Mar 25, 2025 | SCIASCIA THOMASChief Scientific Officer | Sale | 2,631 | $6.60 | $17.4K | Form 4 |
| Mar 21, 2025 | GOOD JENNIFER LPresident & CEO | Sale | 5,263 | $6.58 | $34.6K | Form 4 |
| Mar 10, 2025 | Simon FarrellChief Commercial Officer | Sale | 81,313 | $6.75 | $549.1K | Form 4 |
| Sep 9, 2024 | GOOD JENNIFER LPresident & CEO | Sale | 1,840 | $3.04 | $5.6K | Form 4 |
| Sep 6, 2024 | GOOD JENNIFER LPresident & CEO | Sale | 4,219 | $3.03 | $12.8K | Form 4 |
| Sep 5, 2024 | GOOD JENNIFER LPresident & CEO | Sale | 40,277 | $3.11 | $125.3K | Form 4 |
| Sep 4, 2024 | GOOD JENNIFER LPresident & CEO | Sale | 10,981 | $3.02 | $33.2K | Form 4 |
| Sep 3, 2024 | GOOD JENNIFER LPresident & CEO | Sale | 3,863 | $3.02 | $11.7K | Form 4 |
| Aug 27, 2024 | Meeker David PDirector | Sale | 4,555 | $2.93 | $13.3K | Form 4 |
| Aug 19, 2024 | SCIASCIA THOMASChief Scientific Officer | Sale | 16,496 | $2.96 | $48.8K | Form 4 |
| Aug 16, 2024 | SCIASCIA THOMASChief Scientific Officer | Sale | 18,660 | $2.76 | $51.5K | Form 4 |
| Aug 15, 2024 | SCIASCIA THOMASChief Scientific Officer | Sale | 12,745 | $2.79 | $35.6K | Form 4 |
| Aug 14, 2024 | SCIASCIA THOMASChief Scientific Officer | Sale | 100 | $2.75 | $275 | Form 4 |
| May 29, 2024 | SCIASCIA THOMASChief Scientific Officer | Sale | 53,368 | $2.55 | $136.1K | Form 4 |
| May 22, 2024 | Delfini LisaChief Financial Officer | Sale | 4,350 | $2.64 | $11.5K | Form 4 |
| May 20, 2024 | GOOD JENNIFER LPresident & CEO | Sale | 25,037 | $2.86 | $71.6K | Form 4 |
| May 10, 2024 | GOOD JENNIFER LPresident & CEO | Sale | 4,578 | $2.90 | $13.3K | Form 4 |
| Oct 11, 2023 | Delfini LisaChief Financial Officer | Sale | 785 | $2.02 | $1.6K | Form 4 |
| Sep 11, 2023 | Delfini LisaChief Financial Officer | Sale | 711 | $2.20 | $1.6K | Form 4 |
All 52 trades can be filtered by person here when JavaScript is on.
From Forms 4 filed with the SEC.
Major holders
Investors who own more than 5% of the shares must tell the SEC: a 13D if they may seek to influence the company, a 13G if they hold passively.
- FMR LLCSCHEDULE 13G/A, 3 filings Feb 5, 2026 to Aug 6, 202635
- New Enterprise Associates 16, L.P.SCHEDULE 13D/A, 8 filings Nov 2, 2021 to May 7, 202636
- VANGUARD GROUP INCSCHEDULE 13G/A, 2 filings Jan 30, 2026 to Mar 27, 202637
- Rubric Capital Management LPSCHEDULE 13G/A, 6 filings Feb 10, 2023 to Feb 13, 202638
- Frazier Life Sciences Public Fund, L.P.SCHEDULE 13G/A, 6 filings Apr 18, 2022 to Nov 14, 202539
- VIKING GLOBAL INVESTORS LPSCHEDULE 13G/A, 6 filings Oct 7, 2022 to Nov 14, 202540
- BlackRockSCHEDULE 13G, 1 filing Oct 17, 202541
- Venrock Healthcare Capital Partners II, L.P.SCHEDULE 13G/A, 5 filings Apr 21, 2022 to Feb 14, 202542
- Rosalind Advisors, Inc.SCHEDULE 13G/A, 6 filings Mar 9, 2022 to Feb 13, 202543
- MAI Capital ManagementSCHEDULE 13G/A, 2 filings Apr 8, 2022 to Jul 10, 202444
- Fairmount Funds Management LLCSC 13G/A, 3 filings Apr 21, 2022 to Feb 14, 202445
- ARMISTICE CAPITAL, LLCSC 13G/A, 2 filings Feb 14, 2022 to Feb 14, 202346
- TPG GP A, LLCSC 13G/A, 2 filings Feb 11, 2022 to Feb 10, 202347
- Steven Michael OliveiraSC 13G, 1 filing Mar 9, 202248
- Invest A/s LundbeckfondSC 13G/A, 1 filing Jan 26, 202249
Money raised
Private offerings the company reported to the SEC on Form D.
Held by these funds
The largest holders among investment managers' 13F reports for the quarter ending Jun 30, 2026, the top 25 of 100. Change is in shares since the quarter before.
| Fund | Shares | Value | Share of the fund | Change |
|---|---|---|---|---|
| NEA Management Company, LLC | 13,222,228 | $246.6M | 15.5% | No change |
| Fmr LLC | 12,562,839 | $234.3M | 0.0% | +4,524,778 |
| BlackRock, Inc. | 11,155,026 | $208.0M | 0.0% | +914,840 |
| Frazier Life Sciences Management, L.P. | 9,939,447 | $185.4M | 4.0% | −100 |
| Wellington Management Group Llp | 5,684,592 | $106.0M | 0.0% | +495,504 |
| Vanguard Capital Management LLC | 5,530,675 | $103.1M | 0.0% | +552,108 |
| Vivo Capital, LLC | 5,094,668 | $95.0M | 8.7% | No change |
| Woodline Partners LP | 4,081,333 | $76.1M | 0.2% | +3,080,551 |
| Vestal Point Capital, LP | 3,100,000 | $57.8M | 1.4% | +933,496 |
| Mpm Bioimpact LLC | 3,073,577 | $57.3M | 3.5% | −224,853 |
| Frontier Capital Management Co LLC | 3,070,740 | $57.3M | 0.5% | +1,076,448 |
| Assenagon Asset Management S.A. | 3,050,628 | $56.9M | 0.0% | New |
| State Street Corp | 3,027,315 | $56.5M | 0.0% | +362,002 |
| Geode Capital Management, LLC | 2,928,068 | $54.6M | 0.0% | +149,837 |
| Marshall Wace, Llp | 2,674,137 | $49.9M | 0.0% | −1,291,882 |
| Eventide Asset Management, LLC | 2,660,000 | $49.6M | 0.7% | +37,694 |
| Rubric Capital Management LP | 2,504,513 | $46.7M | 0.4% | −1,207,860 |
| Artia Global Partners LP | 2,210,852 | $41.2M | 7.8% | +197,250 |
| Acorn Capital Advisors, LLC | 2,144,844 | $40.0M | 10.9% | No change |
| First Light Asset Management, LLC | 2,097,215 | $39.1M | 2.4% | New |
| Pictet Asset Management Holding SA | 2,013,786 | $37.6M | 0.0% | +307,738 |
| Logos Global Management LP | 1,880,000 | $35.1M | 1.5% | −520,000 |
| Affinity Asset Advisors, LLC | 1,800,172 | $33.6M | 1.7% | −200,000 |
| Emerald Advisers, LLC | 1,797,611 | $33.5M | 0.8% | −41,955 |
| Siren, L.L.C. | 1,786,867 | $33.3M | 0.7% | No change |
13F reports cover disclosed long positions in U.S. stocks only.
Sources
The numbers on this page point here. Each one links to the record it came from.
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- 20SEC EDGARChristopher Galletta, Officer
- 21SEC EDGARFrank P. Muscolo, Controller
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- 23SEC EDGARJennifer L. Good, Officer
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- 25SEC EDGARYann Mazabraud, Officer
- 26SEC EDGARJames Cassella V., Board member
- 27SEC EDGARDominick Colangelo, Board member
- 28SEC EDGARAnna Guyer Mitsak, Board member
- 29SEC EDGARAnne Vanlent, Board member
- 30SEC EDGARDavid P. Meeker, Board member
- 31SEC EDGAREdward T. Mathers, Board member
- 32SEC EDGAREran Nadav, Board member
- 33SEC EDGARMette Kirstine Agger, Board member
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