1y return+82.1%S&P 500 +20.9%
These returns are for its stock picks as disclosed on Form 13F: last quarter's holdings, valued at this quarter's prices. They miss trades within each quarter, short positions, options, bonds, cash and fees, so they aren't the returns its clients got.
$100 invested in its stock picks
Since December 31, 2023: $232 against $157 in the S&P 500.2
Checkpoint Capital L.P.S&P 500 (SPY)
Top holdings
At the end of June 30, 2026. Change is in shares since the quarter before.2
| Stock | Value | Share of portfolio | Change |
|---|---|---|---|
| RYTMRhythm Pharmaceuticals Inc | $131.7M | 33.8% | −3.4% |
| ARGXArgenx Se | $121.8M | 31.3% | −14.2% |
| RVMDRevolution Medicines Inc | $76.9M | 19.7% | +56.3% |
| CYTKCytokinetics Inc | $40.5M | 10.4% | +163.9% |
| IRONDisc Medicine Inc | $17.6M | 4.5% | −16.2% |
| TRVITrevi Therapeutics Inc | $1.4M | 0.4% | +50.0% |
Best picks still held
How each current holding has done since the quarter it first appeared in its filings (up to six years back).
| Stock | Held since | Return since | Now worth |
|---|---|---|---|
| RVMDRevolution Medicines Inc | December 31, 2024 | +328.2% | $76.9M |
| ARGXArgenx Se | December 31, 2023 | +143.9% | $121.8M |
| RYTMRhythm Pharmaceuticals Inc | December 31, 2023 | +141.5% | $131.7M |
| TRVITrevi Therapeutics Inc | March 31, 2026 | +56.3% | $1.4M |
| CYTKCytokinetics Inc | September 30, 2025 | +55.0% | $40.5M |
| IRONDisc Medicine Inc | September 30, 2024 | +48.8% | $17.6M |
Sold off last quarter
- SEPNSepterna Inc was $2.4M
- Crinetics Pharmaceuticals InCUSIP 22663K107 was $1.5M
Quarter by quarter
| Quarter | Its picks | S&P 500 |
|---|---|---|
| June 30, 2026 | +32.6% | +14.8% |
| March 31, 2026 | −10.6% | −4.6% |
| December 31, 2025 | +10.2% | +2.4% |
| September 30, 2025 | +39.5% | +7.8% |
| June 30, 2025 | +11.9% | +10.5% |
| March 31, 2025 | −6.6% | −4.6% |
| December 31, 2024 | −4.1% | +2.1% |
| September 30, 2024 | +22.7% | +5.4% |
| June 30, 2024 | +0.2% | +4.0% |
| March 31, 2024 | +3.2% | +10.0% |
Sources
Every number on this page points here. Each one links to the public record.
- 1SEC EDGAR: Checkpoint Capital L.P. Form 13F filingshttps://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=1977548&type=13F-HR&dateb=&owner=include&count=40CIK 1977548
- 2SEC: 13F for the quarter ended June 30, 2026https://www.sec.gov/Archives/edgar/data/1977548/000197754826000005/Filed August 14, 2026 · accession 0001977548-26-000005