Funds · 13F filer · Edina, MN

First Light Asset Management, LLC

$1.6B in 31 U.S. stocks and ETFs at the end of June 30, 2026, as reported to the SEC.1

1y return+91.9%S&P 500 +20.9%
3y return+47.1%S&P 500 +68.5%
5y return+16.0%S&P 500 +74.5%
10y return+472.3%S&P 500 +256.5%

These returns are for its stock picks as disclosed on Form 13F: last quarter's holdings, valued at this quarter's prices. They miss trades within each quarter, short positions, options, bonds, cash and fees, so they aren't the returns its clients got.

$100 invested in its stock picks

Since June 30, 2016: $572 against $357 in the S&P 500.2

First Light Asset Management, LLCS&P 500 (SPY)
$100$57220162026

Top holdings

At the end of June 30, 2026. Change is in shares since the quarter before.2

StockValueShare of portfolioChange
NEONeogenomics Inc$179.2M10.9%+26.2%
SIBNSi-bone Inc$132.6M8.1%+51.8%
AXGNAxogen Inc$126.9M7.7%−31.3%
Apogee Therapeutics IncCUSIP 03770N101$123.5M7.5%+61.3%
PVLAPalvella Therapeutics Inc$118.0M7.2%−21.3%
TWSTTwist Bioscience Corporation$74.9M4.6%−17.2%
ELVNEnliven Therapeutics Inc$69.1M4.2%+574.1%
GHGuardant Health$66.3M4.0%+57.5%
MASS908 Devices Inc$54.7M3.3%+3.5%
AMLXAmylyx Pharmaceuticals Inc$54.3M3.3%−5.2%
WGSGenedx Holdings Corp$53.8M3.3%+222.7%
Simulations Plus IncCUSIP 829214105$51.1M3.1%+6.1%
TNDMTandem Diabetes Care Inc$51.1M3.1%+157.4%
Crinetics Pharmaceuticals IncCUSIP 22663K107$50.9M3.1%+24.9%
NPCENeuropace Inc$45.5M2.8%+16.3%
EWTXEdgewise Therapeutics Inc$44.5M2.7%+9.3%
ANABAnaptys Bio Inc$39.3M2.4%+2.9%
TRVITrevi Therapeutics Inc$39.1M2.4%New
SEPNSepterna Inc$32.3M2.0%+31.4%
TLSITrisalus Life Sciences Inc$29.8M1.8%+29.3%
TECXTectonic Therapeutics Inc$27.5M1.7%+23.6%
HCATHealth Catalyst Inc$25.5M1.5%
BFLYButterfly Network Inc$22.2M1.4%
Establishment Labs HoldingsCUSIP G31249108$21.2M1.3%−19.9%
PCVXVaxcyte Inc$20.1M1.2%+143.4%

Best picks still held

How each current holding has done since the quarter it first appeared in its filings (up to six years back).

StockHeld sinceReturn sinceNow worth
GHGuardant HealthDecember 31, 2022+451.6%$66.3M
AXGNAxogen IncSeptember 30, 2020+297.2%$126.9M
ANABAnaptys Bio IncJune 30, 2023+231.9%$39.3M
BFLYButterfly Network IncDecember 31, 2024+169.9%$22.2M
PVLAPalvella Therapeutics IncSeptember 30, 2025+143.8%$118.0M
TWSTTwist Bioscience CorporationDecember 31, 2024+121.4%$74.9M
Establishment Labs HoldingsCUSIP G31249108March 31, 2025+110.3%$21.2M
MASS908 Devices IncMarch 31, 2025+94.2%$54.7M
Apogee Therapeutics IncCUSIP 03770N101December 31, 2025+75.8%$123.5M
EWTXEdgewise Therapeutics IncDecember 31, 2024+52.2%$44.5M

Sold off last quarter

  • Centessa Pharmaceuticals LimitedCUSIP 152309100 was $62.0M
  • Wave Life Sciences LtdCUSIP Y95308105 was $13.4M
  • VERAVera Therapeutics Inc was $12.6M
  • MDXGMimedx Group Inc was $11.2M
  • SGPSpyglass Pharma Inc was $9.7M
  • ORGOOrganogenesis Holdings Inc was $8.3M

Quarter by quarter

QuarterIts picksS&P 500
June 30, 2026+35.5%+14.8%
March 31, 2026−10.3%−4.6%
December 31, 2025+29.2%+2.4%
September 30, 2025+22.3%+7.8%
June 30, 2025−2.8%+10.5%
March 31, 2025−9.9%−4.6%
December 31, 2024−7.3%+2.1%
September 30, 2024+14.0%+5.4%
June 30, 2024−6.1%+4.0%
March 31, 2024+1.1%+10.0%
December 31, 2023+10.5%+11.2%
September 30, 2023−21.0%−3.6%
June 30, 2023+10.0%+8.3%
March 31, 2023+6.0%+7.0%
December 31, 2022+6.5%+7.1%
September 30, 2022+15.7%−5.3%
June 30, 2022−25.1%−16.5%
March 31, 2022−13.9%−4.9%
December 31, 2021−9.0%+10.7%
September 30, 2021−6.4%+0.3%

Sources

Every number on this page points here. Each one links to the public record.

  1. 1
    CIK 1600004
  2. 2
    Filed August 14, 2026 · accession 0001999371-26-018014