Returns–Not enough quarters yet
These returns are for its stock picks as disclosed on Form 13F: last quarter's holdings, valued at this quarter's prices. They miss trades within each quarter, short positions, options, bonds, cash and fees, so they aren't the returns its clients got.
Top holdings
At the end of June 30, 2026. Change is in shares since the quarter before.2
| Stock | Value | Share of portfolio | Change |
|---|---|---|---|
| PTGXProtagonist Therapeutics Inc | $26.9M | 12.4% | −4.5% |
| STTKShattuck Labs Inc | $25.9M | 11.9% | +18.3% |
| CMPSCompass Pathways PLC | $25.1M | 11.6% | −12.2% |
| GPCRStructure Therapeutics Inc | $16.8M | 7.7% | +134.5% |
| VORVor Biopharma Inc | $16.4M | 7.5% | −11.1% |
| RYTMRhythm Pharmaceuticals Inc | $14.6M | 6.7% | +4.5% |
| PVLAPalvella Therapeutics Inc Ne | $13.7M | 6.3% | +8.7% |
| XENEXenon Pharmaceuticals Inc | $11.1M | 5.1% | |
| ZBIOZenas Biopharma Inc | $10.8M | 5.0% | |
| ORICOric Pharmaceuticals Inc | $7.6M | 3.5% | +34.9% |
| IVAInventiva Sa | $6.8M | 3.1% | +34.1% |
| Crescent Biopharma Inc.CUSIP G2545C104 | $6.7M | 3.1% | |
| PCVXVaxcyte Inc | $6.2M | 2.9% | +12.6% |
| COGTCogent Biosciences Inc | $5.1M | 2.3% | |
| VSTMVerastem Inc | $5.0M | 2.3% | |
| IRONDisc Medicine Inc | $3.9M | 1.8% | |
| Pharvaris N VCUSIP N69605108 | $3.7M | 1.7% | New |
| ZLABZai Lab Ltd | $3.5M | 1.6% | |
| BIOABioage Labs Inc | $2.5M | 1.1% | New |
| LBRXLb Pharmaceuticals Inc | $2.2M | 1.0% | New |
| EVMNEvommune Inc | $1.6M | 0.7% | −35.3% |
| ACETAdicet Bio Inc | $1.4M | 0.6% |
Best picks still held
How each current holding has done since the quarter it first appeared in its filings (up to six years back).
| Stock | Held since | Return since | Now worth |
|---|---|---|---|
| CMPSCompass Pathways PLC | December 31, 2025 | +105.1% | $25.1M |
| STTKShattuck Labs Inc | December 31, 2025 | +90.1% | $25.9M |
| Crescent Biopharma Inc.CUSIP G2545C104 | December 31, 2025 | +51.8% | $6.7M |
| PVLAPalvella Therapeutics Inc Ne | December 31, 2025 | +46.0% | $13.7M |
| VORVor Biopharma Inc | December 31, 2025 | +40.7% | $16.4M |
| PTGXProtagonist Therapeutics Inc | December 31, 2025 | +40.3% | $26.9M |
| XENEXenon Pharmaceuticals Inc | December 31, 2025 | +34.7% | $11.1M |
| ORICOric Pharmaceuticals Inc | December 31, 2025 | +32.4% | $7.6M |
| PCVXVaxcyte Inc | December 31, 2025 | +26.0% | $6.2M |
| COGTCogent Biosciences Inc | December 31, 2025 | +9.0% | $5.1M |
Sold off last quarter
- Terns Pharmaceuticals IncCUSIP 880881107 was $31.9M
- CMPXCompass Therapeutics Inc was $4.5M
- Oculis Holding AgCUSIP H5870P102 was $4.0M
- Kalvista Pharmaceuticals IncCUSIP 483497103 was $2.7M
- SMMTSummit Therapeutics Inc was $1.7M
Quarter by quarter
| Quarter | Its picks | S&P 500 |
|---|---|---|
| June 30, 2026 | +10.0% | +14.8% |
| March 31, 2026 | +14.9% | −4.6% |
Sources
Every number on this page points here. Each one links to the public record.
- 1SEC EDGAR: NEXTBio Capital Management LP Form 13F filingshttps://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=2038158&type=13F-HR&dateb=&owner=include&count=40CIK 2038158
- 2SEC: 13F for the quarter ended June 30, 2026https://www.sec.gov/Archives/edgar/data/2038158/000117266126003533/Filed August 14, 2026 · accession 0001172661-26-003533