Photo: Petty Officer 2nd Class Clayton Wren, Public domain, via Wikimedia Commons²

Isaac Guerendo

Running Back, San Francisco 49ers · #31.

Player facts

Team: San Francisco 49ers
Position: Running Back
Number: 31
Born: Jun 28, 2000 (age 26)
Birthplace: Clayton, IN, USA
Height: 6' 0"
Weight: 221 lbs
College: Louisville
Experience: 3 seasons
Status: Day-To-Day

Stats

2025 Offense

	CAR	YDS	AVG	TD	LNG	REC	YDS	AVG	TD	LNG	FUM	LST
Regular Season	-	-	-	-	-	-	-	-	-	-	-	-
Career	84	420	5.0	4	76	15	152	10.1	0	40	3	1

Recent games

			Rushing					Receiving					Fumbles
Date	Opponent	Result	CAR	YDS	AVG	TD	LNG	REC	YDS	AVG	TD	LNG	FUM	LST
Sun, Dec 14	vs TEN	W 37-24	0	0	0.0	0	0	0	0	0.0	0	0	0	0
Sun, Nov 30	@ CLE	W 26-8	0	0	0.0	0	0	0	0	0.0	0	0	0	0
Mon, Nov 24	vs CAR	W 20-9	0	0	0.0	0	0	0	0	0.0	0	0	0	0
Sun, Nov 16	@ ARI	W 41-22	0	0	0.0	0	0	0	0	0.0	0	0	0	0
Sun, Nov 9	vs LAR	L 42-26	0	0	0.0	0	0	0	0	0.0	0	0	0	0

Last 5 games. Click a game for its box score.

About

Isaac Guerendo (gwy-REN-doh; born June 28, 2000) is an American professional football running back and kickoff returner for the San Francisco 49ers of the National Football League (NFL). He played college football for the Wisconsin Badgers and Louisville Cardinals.

From Wikipedia’s article on Isaac Guerendo, shared under CC BY-SA 4.0.¹

Background

Early life

Guerendo was born in Clayton, Indiana and attended Avon High School in Avon, Indiana. As a junior, he hauled in 19 receptions for 596 yards and six touchdowns. Guerendo had a breakout senior season, bringing in 54 receptions for 1,258 yards and 16 touchdowns. As a senior, he was named the Indianapolis Star's Mister Football for wide receivers.

Coming out of high school, Guerendo decided to commit to play college football for the Wisconsin Badgers.

Wisconsin

In Guerendo's first season in 2019, he carried the ball once for one yard, while also making one catch for three yards, and returning one kickoff for 49 yards.

During the COVID shortened 2020 season, Guerendo carried the ball 11 times for 36 yards.

In Week 2 of the 2021 season, Guerendo recorded his first career touchdown on an 82-yard run versus Eastern Michigan. He finished the season with 160 yards and a touchdown of 23 carries, while also racking up two receptions for six yards.

In 2022, Guerendo rushed for 385 yards and five touchdowns on 64 carries, while also notching 17 receptions for 115 yards and a touchdown. At the end of the season, Guerendo decided to enter the NCAA transfer portal.

Guerendo finished his Wisconsin Badger career playing in 20 games carrying the ball 99 times for 582 yards and six touchdowns, while also notching 20 receptions for 124 yards and a touchdown. He graduated from Wisconsin in December 2022 with a bachelor's degree in personal finance.

Louisville

In 2023, Guerendo became a graduate transfer to the University of Louisville, playing for the Louisville Cardinals for his final season of college eligibility. In his Louisville home debut in Week 2 of the 2023 season, Guerendo rushed for 63 yards and a touchdown on 11 carries, while also hauling in four receptions for 47 yards. In Week 10, he had a career performance rushing for 146 yards and three touchdowns in a win over Virginia Tech. In the 2023 Holiday Bowl, Guerendo rushed for a career high 161 yards and three touchdowns, on 23 carries, but the Cardinals lost to USC 42–28.

Guerendo finished the 2023 season with 810 yards and 11 touchdowns on 132 carries, while also making 22 receptions for 234 yards. After the season, he declared for the 2024 NFL draft.

Personal life

Guerendo was born in Indianapolis to Mario and Jennifer Guerendo. Mario is an immigrant from the Central African Republic, and Jen competed in track & field in high school.

From Wikipedia’s article on Isaac Guerendo, shared under CC BY-SA 4.0. Read the full article.¹