Funds · 13F filer · Boston, MA

Mpm Bioimpact LLC

$1.6B in 37 U.S. stocks and ETFs at the end of June 30, 2026, as reported to the SEC.1

1y return+143.5%S&P 500 +20.9%

These returns are for its stock picks as disclosed on Form 13F: last quarter's holdings, valued at this quarter's prices. They miss trades within each quarter, short positions, options, bonds, cash and fees, so they aren't the returns its clients got.

$100 invested in its stock picks

Since September 30, 2023: $238 against $175 in the S&P 500.2

Mpm Bioimpact LLCS&P 500 (SPY)
$97$100$23820232026

Top holdings

At the end of June 30, 2026. Change is in shares since the quarter before.2

StockValueShare of portfolioChange
CGEMCullinan Therapeutics, Inc.$177.2M10.8%+27.2%
AKTSAktis Oncology, Inc.$155.9M9.5%
LQDALiquidia Corporation$110.5M6.7%−1.4%
RVMDRevolution Medicines, Inc.$92.2M5.6%−2.8%
CORTCorcept Therapeutics, Inc.$67.0M4.1%−21.8%
EWTXEdgewise Therapeutics Inc$65.9M4.0%−2.4%
TVTXTravere Therapeutics Inc$63.8M3.9%
DBVTDBV Technologies S A$60.1M3.7%−29.7%
TRVITrevi Therapeutics Inc$57.3M3.5%−6.8%
ALMSAlumis Inc$56.8M3.5%−15.4%
Uniqure NVCUSIP N90064101$56.5M3.4%−10.5%
RAREUltragenyx Pharmaceuticals, Inc.$47.4M2.9%New
RLAYRelay Therapeutics Inc.$45.2M2.8%+2.4%
ABVXAbivax SA$44.8M2.7%+213.6%
DYNDyne Therapeutics, Inc.$42.7M2.6%+36.5%
DNTHDianthus Therapeutics Inc$40.9M2.5%
BIOABIOAGE Labs Inc$40.9M2.5%New
Urogen Pharma LtdCUSIP M96088105$34.3M2.1%−1.1%
MLTXMoonLake Immunotherapeutics$31.3M1.9%−11.3%
PVLAPalvella Therapeutics Inc$31.2M1.9%−1.2%
TSHATaysha Gene Therapies, Inc.$30.6M1.9%New
SNDXSyndax Pharmaceuticals Inc$29.2M1.8%
GLUEMonte Rosa Therapeutics Inc$28.1M1.7%−1.3%
Zura Bio Ltd.CUSIP G9TY5A101$26.4M1.6%New
NTRANatera Inc$25.1M1.5%

Best picks still held

How each current holding has done since the quarter it first appeared in its filings (up to six years back).

StockHeld sinceReturn sinceNow worth
RVMDRevolution Medicines, Inc.September 30, 2021+580.8%$92.2M
TRVITrevi Therapeutics IncMarch 31, 2024+440.6%$57.3M
LQDALiquidia CorporationSeptember 30, 2025+250.6%$110.5M
NTRANatera IncMarch 31, 2024+196.8%$25.1M
ALMSAlumis IncDecember 31, 2025+188.3%$56.8M
STOKStoke Therapeutics IncSeptember 30, 2024+166.2%$23.7M
PVLAPalvella Therapeutics IncSeptember 30, 2025+143.8%$31.2M
DYNDyne Therapeutics, Inc.June 30, 2025+133.3%$42.7M
EWTXEdgewise Therapeutics IncMarch 31, 2024+122.8%$65.9M
CORTCorcept Therapeutics, Inc.March 31, 2026+115.7%$67.0M

Sold off last quarter

  • AGIOAgios Pharmaceuticals Inc was $44.2M
  • XENEXenon Pharmaceuticals Inc was $34.2M
  • EVMNEvommune Inc was $33.5M
  • CYTKCytokinetics Inc was $33.0M
  • CRVSCorvus Pharmaceuticals Inc was $24.5M
  • CLYMClimb Bio Inc was $17.8M
  • ARQTArcutis Biotherapeutics Inc was $17.3M
  • ZYMEZymeworks, Inc. was $14.2M
  • VRDNViridian Therapeutics Inc was $12.7M
  • enGene Holdings, Inc.CUSIP 29286M105 was $12.6M

Quarter by quarter

QuarterIts picksS&P 500
June 30, 2026+34.4%+14.8%
March 31, 2026+14.0%−4.6%
December 31, 2025+31.1%+2.4%
September 30, 2025+21.2%+7.8%
June 30, 2025+1.2%+10.5%
March 31, 2025−17.0%−4.6%
December 31, 2024−13.8%+2.1%
September 30, 2024+3.1%+5.4%
June 30, 2024−8.2%+4.0%
March 31, 2024+22.8%+10.0%
December 31, 2023+16.4%+11.2%
June 30, 2023+8.9%+8.3%
March 31, 2023−5.7%+7.0%
December 31, 2022−10.7%+7.1%
September 30, 2022+1.4%−5.3%
June 30, 2022−5.2%−16.5%
March 31, 2022−31.2%−4.9%
December 31, 2021−12.5%+10.7%
September 30, 2021−18.2%+0.3%

Sources

Every number on this page points here. Each one links to the public record.

  1. 1
    CIK 1687078
  2. 2
    Filed August 14, 2026 · accession 0001193125-26-352199